DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2918 and Hsp70-15

DIOPT Version :9

Sequence 1:	NP_001162645.1	Gene:	CG2918 / 31215	FlyBaseID:	FBgn0023529	Length:	923	Species:	Drosophila melanogaster
Sequence 2:	NP_001319422.1	Gene:	Hsp70-15 / 844332	AraportID:	AT1G79920	Length:	736	Species:	Arabidopsis thaliana

Alignment Length:	729	Identity:	173/729 - (23%)
Similarity:	323/729 - (44%)	Gaps:	92/729 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 AVMSVDLGSEWMKVGVV-SPGVPMEIALNRESKRKTPAILAFRDGTRTIGEDAQTIGIKDPNSAY 84
            :|:..|.|:|...|.|. ..|:  ::.||.||.|:||||:.|.|..|.||.......:.:|.::.
plant     2 SVVGFDFGNENCLVAVARQRGI--DVVLNDESNRETPAIVCFGDKQRFIGTAGAASTMMNPKNSI 64

  Fly    85 GYLLDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTVVFRK--SDTDEFSVEELVAQLLVKAKQF 147
            ..:..|:|:...:|.:....|..| :::...|:...::...  .:...|:..:::..:|...|..
plant    65 SQIKRLIGRQFSDPELQRDIKSLP-FSVTEGPDGYPLIHANYLGEIRAFTPTQVMGMMLSNLKGI 128

  Fly   148 AQESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYGVFHRGEINETA 212
            |::::...:.:|.:.:|.||...:|.|:|.||.:|.|..|.||::..|.||.||:: :.::.|..
plant   129 AEKNLNTAVVDCCIGIPVYFTDLQRRAVLDAATIAGLHPLHLIHETTATALAYGIY-KTDLPEND 192

  Fly   213 QY-FLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFN 276
            |. ..|.|:|.......:..:   |..|       :::|...:||:|||.:....|.::.|.:|.
plant   193 QLNVAFIDIGHASMQVCIAGF---KKGQ-------LKILSHAFDRSLGGRDFDEVLFNHFAAKFK 247

  Fly   277 ALKKTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQLCEDL 341
              .:.|.||:.:.:|..:|.....:||.|||||......||.|:.:.|.:..:.||:.|::...:
plant   248 --DEYKIDVSQNAKASLRLRATCEKLKKVLSANPMAPLNIECLMAEKDVRGVIKREEFEEISIPI 310

  Fly   342 WPRATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIKQELGKNLNADESATMGAVY 406
            ..|..:|||:||:.:.|:::.::.|.:.|.|:|||.:.:.:.....:|..:.:||.|..:.|...
plant   311 LERVKRPLEKALSDAGLTVEDVHMVEVVGSGSRVPAMIKILTEFFGKEPRRTMNASECVSRGCAL 375

  Fly   407 KAADLSAGFKVKKFVVKDATLFPLQVSF-----ERDPGDGAAVKQVKRALFALMNPYPQKKVITF 466
            :.|.||..|||::|.|.::  ||..:|.     ..|..:|....|....:|...||.|..|.:||
plant   376 QCAILSPTFKVREFQVHES--FPFSISLAWKGAATDAQNGGTENQQSTIVFPKGNPIPSVKALTF 438

  Fly   467 NKHTDDFEFYVNYADL-DRYSKEEIA--ALGSLNVTKVQLKQVKELLEKSKKELVDNKGIKAYFY 528
            .: :..|...|.|:|: |..:..:|:  .:|....:|.         |::|.::.....:.....
plant   439 YR-SGTFSIDVQYSDVNDLQAPPKISTYTIGPFQSSKG---------ERAKLKVKVRLNLHGIVS 493

  Fly   529 LDDSGIFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEEKKDNSEQEEAANAGEEP 593
            ::.:.:.....||....|.:.|:.|..|:                     |.:..|.|..:|:..
plant   494 VESATLLEEEEVEVSVTKDQSEETAKMDT---------------------DKASAEAAPASGDSD 537

  Fly   594 ---SKSEDNEKAKEEDASKEQKSEESTKQDTEAKNETIKLVTVKSPVTYESQTQFVVPLVGSAYD 655
               ..::|...|...|....:.:|:..:.:|::|        .|:|.....:|.  |||....|
plant   538 VNMQDAKDTSDATGTDNGVPESAEKPVQMETDSK--------AKAPKKKVKKTN--VPLSELVY- 591

  Fly   656 QSVAKLAAINKAEEQRVRL----------ESAFNALEAHIIEVQQKLDEESYAKCATAEEK---- 706
             ...|...:.||.|:...:          :...||:|:::.:::.||.::......|...|
plant   592 -GALKTVEVEKAVEKEFEMALQDRVMEETKDRKNAVESYVYDMRNKLSDKYQNISLTRRGKHSWR 655

  Fly   707 --EKLLAECSTLGE 718
              .||...|..:|:
plant   656 ICRKLRIGCMKMGK 669

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	150/617 (24%)
		HYOU1-like_NBD	23..409	CDD:212672	103/389 (26%)
		TAF4	<572..>627	CDD:296797	10/57 (18%)
Hsp70-15	NP_001319422.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810