DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2918 and AT1G11660

DIOPT Version :9

Sequence 1:	NP_001162645.1	Gene:	CG2918 / 31215	FlyBaseID:	FBgn0023529	Length:	923	Species:	Drosophila melanogaster
Sequence 2:	NP_001322125.1	Gene:	AT1G11660 / 837710	AraportID:	AT1G11660	Length:	763	Species:	Arabidopsis thaliana

Alignment Length:	879	Identity:	238/879 - (27%)
Similarity:	384/879 - (43%)	Gaps:	131/879 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 AVMSVDLGSEWMKVGVVSP-GVPMEIALNRESKRKTPAILAFRDGTRTIGEDAQTIGIKDPNSAY 84
            :|:..|:|:|...:.|... |:  ::.||.||.|:.||:::|.:..|.:|..|.......|.|..
plant     2 SVVGFDVGNENCVIAVAKQRGI--DVLLNDESNRENPAMVSFGEKQRFMGAAAAASATMHPKSTI 64

  Fly    85 GYLLDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTVVFR---KSDTDEFSVEELVAQLLVKAKQ 146
            ..|..|:|:....|.|....:.||:.  ..:.....:..|   ..:...||..:::..||...||
plant    65 SQLKRLIGRKFREPDVQNDLRLFPFE--TSEDSDGGIQIRLRYMGEIQSFSPVQILGMLLSHLKQ 127

  Fly   147 FAQESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYGVFHRGEI-NE 210
            .|::|::.|:::||:.:|.||..::|.|.|.||.:|.|:.|:|::|..|.||.||::....: |.
plant   128 IAEKSLKTPVSDCVIGIPSYFTNSQRLAYLDAAAIAGLRPLRLMHDSTATALGYGIYKTDLVANS 192

  Fly   211 TAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEF 275
            :..|.:|.|:|...|...|.|::          :..::|....:||.|||.:....|.::.|.||
plant   193 SPTYIVFIDIGHCDTQVCVASFE----------SGSMRVRSHAFDRNLGGRDFDEVLFNHFALEF 247

  Fly   276 NALKKTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQLCED 340
            .  :|...||.|:.:|..:|.....::|.|||||.|....||.|:|:.|.:..:.||:.|||...
plant   248 K--EKYNIDVYTNTKACVRLRASCEKVKKVLSANAEAQLNIECLMEEKDVRSFIKREEFEQLSAG 310

  Fly   341 LWPRATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIKQELGKNLNADESATMGAV 405
            |..|...|.::|||.|.||||.|:.|.|.|.|:|:|.:.:.:.::.|:|||:.:||.|....|..
plant   311 LLERLIVPCQKALADSGLSLDQIHSVELVGSGSRIPAISKMLSSLFKRELGRTVNASECVARGCA 375

  Fly   406 YKAADLSAGFKVKKFVVKDATLFPLQVSFERDPGDGAAVKQVKRALFALMNPYPQKKVITFNK-H 469
            .:.|.||..|:|:.:.|:|:  :|..:.|..|  .|.........||.....:|..||:|.:: :
plant   376 LQCAMLSPVFRVRDYEVQDS--YPFAIGFSSD--KGPINTPSNELLFPKGQIFPSVKVLTLHREN 436

  Fly   470 TDDFE-FYVNYADLDRYSKEEIAA--LGSLNVTKVQLKQVKELLEKSKKELVDNKGIKAYFYLDD 531
            |...| ||.|:.:|......:|::  :|..:::..:..:||..::.:...:|.
plant   437 TFQLEAFYANHNELSPDIPTQISSFMIGPFHISHGEAARVKVRVQLNLHGIVT------------ 489

  Fly   532 SGIFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEEKKDNSEQEEAANAGEEPSKS 596
              |...|.:||..|....|:...|::              .:....||.|....:.:.|.||...
plant   490 --IDSATLIEYHKENITSEEMISEEN--------------HQSSAMKDGSLDPSSGSIGNEPKAI 538

  Fly   597 EDNEKAKEEDASKEQKSEESTKQDTEAKNETIKLVTVKSPVTYESQTQFVVPLVGSAYDQSVAKL 661
            :..|.....:.|.....:|.    :|||.....||
plant   539 KRMEIPVVANVSGALTKDEL----SEAKQRENSLV------------------------------ 569

  Fly   662 AAINKAEEQRVRLESA---FNALEAHIIEVQQKLDEESYAKCATAEEKEKLLAECSTLGEWLYED 723
                   ||.:::||.   .||||:.:.|::.|: ..:|...||..|:|.:........||||||
plant   570 -------EQDLKMESTKDKKNALESFVYEMRDKM-LNTYRNTATESERECIARNLQETEEWLYED 626

  Fly   724 LEDPKAEIYEEKLAQLKKLSNVFLARHWEHEERPEAIKALKGMIDGAEKFLVTGRNLTKDTNPEK 788
            .:|.....|.|||..:|||.:....|..:.|||.:|.|.|.       |.:...|...:...|.:
plant   627 GDDESENAYIEKLNDVKKLIDPIENRFKDGEERVQASKDLL-------KTIADNRMAAESLPPPR 684

  Fly   789 DVFTQVEIDTLDKVITETNAWLKTETAAQKKLAKNADIRLTVKDITDKMSLLDREVKYLVNKIKI 853
               ....:|...|    ...||..:|..|:.|.|:|:..|...:|..|...|:...||      |
plant   685 ---KNAVLDECHK----AERWLHEKTTEQESLPKDANPELQSAEIRRKADALNATCKY------I 736

  Fly   854 WKPKVKPAAEKEKKKEEEVVASGSGDDTKSEDAE 887
            .|....||      |.|.   :||....||:|.|
plant   737 GKSNSPPA------KPEH---NGSYGSRKSDDME 761

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	169/611 (28%)
		HYOU1-like_NBD	23..409	CDD:212672	122/390 (31%)
		TAF4	<572..>627	CDD:296797	12/54 (22%)
AT1G11660	NP_001322125.1	HSPA4_like_NDB	2..382	CDD:212670	124/395 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810