DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2918 and BIP3

DIOPT Version :9

Sequence 1:	NP_001162645.1	Gene:	CG2918 / 31215	FlyBaseID:	FBgn0023529	Length:	923	Species:	Drosophila melanogaster
Sequence 2:	NP_172382.4	Gene:	BIP3 / 837429	AraportID:	AT1G09080	Length:	675	Species:	Arabidopsis thaliana

Alignment Length:	764	Identity:	195/764 - (25%)
Similarity:	316/764 - (41%)	Gaps:	152/764 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SALLAGIALSQG-----AAVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRT 67
            :||::.:|: :|     ..|:.:|||:.:..|||.. ...:||..|.:..|.||:.:||.|..|.
plant    34 AALMSSLAI-EGEEQKLGTVIGIDLGTTYSCVGVYH-NKHVEIIANDQGNRITPSWVAFTDTERL 96

  Fly    68 IGEDAQTIGIKDPNSAYGYLLDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTVVFRKSDTDEFS 132
            |||.|:....|:|.........|:|:..|:|.|....|..||..:..|.:....|..|.:...||
plant    97 IGEAAKNQAAKNPERTIFDPKRLIGRKFDDPDVQRDIKFLPYKVVNKDGKPYIQVKVKGEEKLFS 161

  Fly   133 VEELVAQLLVKAKQFAQESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVA 197
            .||:.|.:|.|.|:.|:..:.:.|.:.|:|||.||..|:|:|...|..:|.|.|:::||:....|
plant   162 PEEISAMILTKMKETAEAFLGKKIKDAVITVPAYFNDAQRQATKDAGAIAGLNVVRIINEPTGAA 226

  Fly   198 LNYGVFHR-GEINETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGL 261
            :.||:..: ||.|     .|.||:|......::::..          |.|.:||....|..|||.
plant   227 IAYGLDKKGGESN-----ILVYDLGGGTFDVSILTID----------NGVFEVLSTSGDTHLGGE 276

  Fly   262 EIQLRLRDYLAQEFNALKKTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFK 326
            :...|:.||..:...  ||...|::...:||.||.:|....|..||...:...:||:|.:.:||.
plant   277 DFDHRVMDYFIKLVK--KKYNKDISKDHKALGKLRRECELAKRSLSNQHQVRVEIESLFDGVDFS 339

  Fly   327 LPVTREKLEQLCEDLWPRATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIK-QEL 390
            .|:||.:.|:|..||:.:..:|:::||..:.|....|::::|.||.||:|:||:.:|.... :|.
plant   340 EPLTRARFEELNMDLFKKTMEPVKKALKDAGLKKSDIDEIVLVGGSTRIPKVQQMLKDFFDGKEP 404

  Fly   391 GKNLNADESATMGAVYKAADLS--AGFKVKKFVVKDATLFPLQVSFERDPGDGAAVKQVKRALFA 453
            .|..|.||:...||..:...||  .|.:.:..::.|..  ||.:..|...|             .
plant   405 SKGTNPDEAVAYGAAVQGGVLSGEGGEETQNILLLDVA--PLSLGIETVGG-------------V 454

  Fly   454 LMNPYPQKKVITFNKHTDDFEFYVNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELV 518
            :.|..|:..||...|.    :.:..|.|..        ...::||.:.:....|:..|..|.:|.
plant   455 MTNIIPRNTVIPTKKS----QVFTTYQDQQ--------TTVTINVYEGERSMTKDNRELGKFDLT 507

  Fly   519 D----NKG---IKAYFYLDDSGIFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEE 576
            .    .:|   |:..|.:|.:||.:.          |.||         |...|...:.....:.
plant   508 GILPAPRGVPQIEVTFEVDANGILQV----------KAED---------KVAKTSQSITITNDKG 553

  Fly   577 KKDNSEQEEAANAGEEPSKSEDNEKAKEEDASKEQKSEESTKQDTEAKNETIKLVTVKSPVTYES 641
            :....|.||.....||         ..|||...::|.:...|.:|...|       :||.|.
plant   554 RLTEEEIEEMIREAEE---------FAEEDKIMKEKIDARNKLETYVYN-------MKSTVA--- 599

  Fly   642 QTQFVVPLVGSAYDQSVAKLAAINKAEEQRVRLESAFNALEAHIIEVQQKLDEESYAKCATAEEK 706
                                                               |:|..||..:.|:|
plant   600 ---------------------------------------------------DKEKLAKKISDEDK 613

  Fly   707 EKLLAECSTLGEWLYEDLEDPKAEIYEEKLAQLKKLSNVFLARHWEHEE 755
            ||:........|||.|::...| |.|:|||.:::.:.:..:...:|..|
plant   614 EKMEGVLKEALEWLEENVNAEK-EDYDEKLKEVELVCDPVIKSVYEKTE 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	167/613 (27%)
		HYOU1-like_NBD	23..409	CDD:212672	123/387 (32%)
		TAF4	<572..>627	CDD:296797	12/54 (22%)
BIP3	NP_172382.4	HSPA5-like_NBD	50..423	CDD:212681	124/390 (32%)
BIP3	NP_172382.4	PTZ00009	53..658	CDD:240227	188/739 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810