DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2918 and BIP2

DIOPT Version :9

Sequence 1:	NP_001162645.1	Gene:	CG2918 / 31215	FlyBaseID:	FBgn0023529	Length:	923	Species:	Drosophila melanogaster
Sequence 2:	NP_001331824.1	Gene:	BIP2 / 834207	AraportID:	AT5G42020	Length:	673	Species:	Arabidopsis thaliana

Alignment Length:	783	Identity:	194/783 - (24%)
Similarity:	323/783 - (41%)	Gaps:	166/783 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 AVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRTIGEDAQTIGIKDPNSAYG 85
            :|:.:|||:.:..|||...| .:||..|.:..|.||:.:.|.|..|.|||.|:.....:|.....
plant    41 SVIGIDLGTTYSCVGVYKNG-HVEIIANDQGNRITPSWVGFTDSERLIGEAAKNQAAVNPERTVF 104

  Fly    86 YLLDLLGKTIDNPIVDLYRKRFPY--YNIVGDPERNTVVFRKSDTDEFSVEELVAQLLVKAKQFA 148
            .:..|:|:..::..|...||..||  .|..|.|... |..:..:|..||.||:.|.:|.|.|:.|
plant   105 DVKRLIGRKFEDKEVQKDRKLVPYQIVNKDGKPYIQ-VKIKDGETKVFSPEEISAMILTKMKETA 168

  Fly   149 QESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYGVFHR-GEINETA 212
            :..:.:.|.:.|:|||.||..|:|:|...|..:|.|.|.::||:..|.|:.||:..: ||.|
plant   169 EAYLGKKIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKN--- 230

  Fly   213 QYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFNA 277
              .|.:|:|......:|::..          |.|.:||....|..|||.:...|:.:|..:...
plant   231 --ILVFDLGGGTFDVSVLTID----------NGVFEVLSTNGDTHLGGEDFDHRIMEYFIKLIK- 282

  Fly   278 LKKTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQLCEDLW 342
             ||.:.|::...:||.||.:|..|.|..||:..:...:||:|.:.:|...|:||.:.|:|..||:
plant   283 -KKHQKDISKDNKALGKLRRECERAKRALSSQHQVRVEIESLFDGVDLSEPLTRARFEELNNDLF 346

  Fly   343 PRATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIK-QELGKNLNADESATMGAVY 406
            .:...|:::|:..:.|....|::::|.||.||:|:||:.:|...: :|..|.:|.||:...||..
plant   347 RKTMGPVKKAMDDAGLQKSQIDEIVLVGGSTRIPKVQQLLKDFFEGKEPNKGVNPDEAVAYGAAV 411

  Fly   407 KAADLS--AGFKVKKFVVKDATLFPLQVSFERDPGDGAAVKQVKRALFALMNPYPQKKVITFNKH 469
            :...||  .|.:.|..::.|..  ||.:..|       .|..|...|.......|.||...|..:
plant   412 QGGILSGEGGDETKDILLLDVA--PLTLGIE-------TVGGVMTKLIPRNTVIPTKKSQVFTTY 467

  Fly   470 TD-DFEFYVNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELVDNKG---IKAYFYLD 530
            .| .....:...:.:|...::...||..::|.|....               :|   |:..|.:|
plant   468 QDQQTTVSIQVFEGERSLTKDCRLLGKFDLTGVPPAP---------------RGTPQIEVTFEVD 517

  Fly   531 DSGIFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEEKKDNSEQEEAANAGEEPSK 595
            .:||...          |.||.|                                   :|:....
plant   518 ANGILNV----------KAEDKA-----------------------------------SGKSEKI 537

  Fly   596 SEDNEK---AKEEDASKEQKSEESTKQDTEAKNETIKLVTVKSPVTYESQTQFVVPLVGSAYDQS 657
            :..|||   ::||.....:::||..::|.:.|.:.
plant   538 TITNEKGRLSQEEIDRMVKEAEEFAEEDKKVKEKI------------------------------ 572

  Fly   658 VAKLAAINKAEEQRVRLESAFNALEAHIIEVQQKL-DEESYAKCATAEEKEKLLAECSTLGEWLY 721
                              .|.||||.::..::.:: |::..|.....:||||:.|......|||.
plant   573 ------------------DARNALETYVYNMKNQVSDKDKLADKLEGDEKEKIEAATKEALEWLD 619

  Fly   722 EDLEDPKAEIYEEKLAQLKKLSNVFLARHWEHEERPEAIKALKGMIDGAEKFLVTGRNLTKDTNP 786
            |:....|.| |:|||.:::.:.|..:.          |:....|...||     .|.:.|::.:.
plant   620 ENQNSEKEE-YDEKLKEVEAVCNPIIT----------AVYQRSGGAPGA-----GGESSTEEEDE 668

  Fly   787 EKD 789
            ..|
plant   669 SHD 671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	163/615 (27%)
		HYOU1-like_NBD	23..409	CDD:212672	122/389 (31%)
		TAF4	<572..>627	CDD:296797	10/57 (18%)
BIP2	NP_001331824.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810