DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2918 and BIP1

DIOPT Version :9

Sequence 1:	NP_001162645.1	Gene:	CG2918 / 31215	FlyBaseID:	FBgn0023529	Length:	923	Species:	Drosophila melanogaster
Sequence 2:	NP_198206.1	Gene:	BIP1 / 832950	AraportID:	AT5G28540	Length:	669	Species:	Arabidopsis thaliana

Alignment Length:	764	Identity:	193/764 - (25%)
Similarity:	314/764 - (41%)	Gaps:	170/764 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LVLLLSALLAGIALSQGAAVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRT 67
            |..|.||:.....|   .:|:.:|||:.:..|||...| .:||..|.:..|.||:.:.|.|..|.
plant    21 LFALSSAIEEATKL---GSVIGIDLGTTYSCVGVYKNG-HVEIIANDQGNRITPSWVGFTDSERL 81

  Fly    68 IGEDAQTIGIKDPNSAYGYLLDLLGKTIDNPIVDLYRKRFPY--YNIVGDPERNTVVFRKSDTDE 130
            |||.|:.....:|......:..|:|:..::..|...||..||  .|..|.|... |..:..:|..
plant    82 IGEAAKNQAAVNPERTVFDVKRLIGRKFEDKEVQKDRKLVPYQIVNKDGKPYIQ-VKIKDGETKV 145

  Fly   131 FSVEELVAQLLVKAKQFAQESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAA 195
            ||.||:.|.:|.|.|:.|:..:.:.|.:.|:|||.||..|:|:|...|..:|.|.|.::||:..|
plant   146 FSPEEISAMILTKMKETAEAYLGKKIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTA 210

  Fly   196 VALNYGVFHR-GEINETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLG 259
            .|:.||:..: ||.|     .|.:|:|......:|::..          |.|.:||....|..||
plant   211 AAIAYGLDKKGGEKN-----ILVFDLGGGTFDVSVLTID----------NGVFEVLSTNGDTHLG 260

  Fly   260 GLEIQLRLRDYLAQEFNALKKTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDID 324
            |.:...|:.:|..:...  ||.:.|::...:||.||.:|..|.|..||:..:...:||:|.:.:|
plant   261 GEDFDHRVMEYFIKLIK--KKHQKDISKDNKALGKLRRECERAKRALSSQHQVRVEIESLFDGVD 323

  Fly   325 FKLPVTREKLEQLCEDLWPRATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIK-Q 388
            |..|:||.:.|:|..||:.:...|:::|:..:.|....|::::|.||.||:|:||:.:|...: :
plant   324 FSEPLTRARFEELNNDLFRKTMGPVKKAMDDAGLQKSQIDEIVLVGGSTRIPKVQQLLKDFFEGK 388

  Fly   389 ELGKNLNADESATMGAVYKAADLS--AGFKVKKFVVKDATLFPLQVSFERDPGDGAAVKQVKRAL 451
            |..|.:|.||:...||..:...||  .|.:.|..::.|..  ||.:..|       .|..|...|
plant   389 EPNKGVNPDEAVAYGAAVQGGILSGEGGDETKDILLLDVA--PLTLGIE-------TVGGVMTKL 444

  Fly   452 FALMNPYPQKKVITFNKHTDDFEFYVNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKE 516
            .......|.||...|..:.|                       ......:|:.:.:..|.|..:.
plant   445 IPRNTVIPTKKSQVFTTYQD-----------------------QQTTVSIQVFEGERSLTKDCRL 486

  Fly   517 L--VDNKG----------IKAYFYLDDSGIFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKL 569
            |  .|..|          |:..|.:|.:||...          |.||.|
plant   487 LGKFDLNGIPPAPRGTPQIEVTFEVDANGILNV----------KAEDKA---------------- 525

  Fly   570 FTKEGEEKKDNSEQEEAANAGEEPSKSEDNEK---AKEEDASKEQKSEESTKQDTEAKNETIKLV 631
                               :|:....:..|||   ::||.....:::||..::|.:.|.:.
plant   526 -------------------SGKSEKITITNEKGRLSQEEIDRMVKEAEEFAEEDKKVKEKI---- 567

  Fly   632 TVKSPVTYESQTQFVVPLVGSAYDQSVAKLAAINKAEEQRVRLESAFNALEAHIIEVQQKL-DEE 695
                                                        .|.||||.::..::.:: |::
plant   568 --------------------------------------------DARNALETYVYNMKNQVNDKD 588

  Fly   696 SYAKCATAEEKEKLLAECSTLGEWLYEDLEDPKAEIYEEKLAQLKKLSN 744
            ..|.....:||||:.|......|||.|:....|.| |:|||.:::.:.|
plant   589 KLADKLEGDEKEKIEAATKEALEWLDENQNSEKEE-YDEKLKEVEAVCN 636

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	164/623 (26%)
		HYOU1-like_NBD	23..409	CDD:212672	123/389 (32%)
		TAF4	<572..>627	CDD:296797	10/57 (18%)
BIP1	NP_198206.1	PTZ00009	35..644	CDD:240227	188/747 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810