DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2918 and HSP70T-2

DIOPT Version :9

Sequence 1:	NP_001162645.1	Gene:	CG2918 / 31215	FlyBaseID:	FBgn0023529	Length:	923	Species:	Drosophila melanogaster
Sequence 2:	NP_180771.1	Gene:	HSP70T-2 / 817771	AraportID:	AT2G32120	Length:	563	Species:	Arabidopsis thaliana

Alignment Length:	415	Identity:	86/415 - (20%)
Similarity:	173/415 - (41%)	Gaps:	73/415 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 MSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRTIGEDAQTIGIKD--PNSAYG 85
            :.:|:|:....:.|.: |..:.|..|..:::...:.:.|:|.....|...|....::  ..:|..
plant    31 LGIDIGTSQCSIAVWN-GSQVHILRNTRNQKLIKSFVTFKDEVPAGGVSNQLAHEQEMLTGAAIF 94

  Fly    86 YLLDLLGKTIDNPIVDLYRKRFPYY-------------NIVGDPERNTVVFRKSDTDEFSVEELV 137
            .:..|:|:...:|:|.. .|..|:.             .:|.:..|:|           :.||::
plant    95 NMKRLVGRVDTDPVVHA-SKNLPFLVQTLDIGVRPFIAALVNNAWRST-----------TPEEVL 147

  Fly   138 AQLLVKAKQFAQESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYG- 201
            |..||:.:..|:..:::|:...|||||..|.:.:......|..:|.|.||:|:.:..|:||.|.
plant   148 AIFLVELRLMAEAQLKRPVRNVVLTVPVSFSRFQLTRFERACAMAGLHVLRLMPEPTAIALLYAQ 212

  Fly   202 ----VFHRGEINETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLE 262
                ..|....:.:.:..:.::|||.....||          |.....|.|:..:. ...:||.:
plant   213 QQQMTTHDNMGSGSERLAVIFNMGAGYCDVAV----------TATAGGVSQIKALA-GSPIGGED 266

  Fly   263 IQLRLRDYLAQEFNALKKTKTDVTTSPRALAKLFKEAGRLKNVLSANT-EFFAQIENLIEDIDF- 325
            |                     :..:.|.:|...:||..|..|.:.:. ......||:..::|.
plant   267 I---------------------LQNTIRHIAPPNEEASGLLRVAAQDAIHRLTDQENVQIEVDLG 310

  Fly   326 ---KLPVTREKL--EQLCEDLWPRATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAV 385
               |:....::|  |::.:.::....:.:.:.|..:.::...|:.:|:.||.:.:|:|:..||.|
plant   311 NGNKISKVLDRLEFEEVNQKVFEECERLVVQCLRDARVNGGDIDDLIMVGGCSYIPKVRTIIKNV 375

  Fly   386 IKQ-ELGKNLNADESATMGAVYKAA 409
            .|: |:.|.:|..|:|..||..:.|
plant   376 CKKDEIYKGVNPLEAAVRGAALEGA 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	86/415 (21%)
		HYOU1-like_NBD	23..409	CDD:212672	85/413 (21%)
		TAF4	<572..>627	CDD:296797
HSP70T-2	NP_180771.1	HSP70_NBD	31..400	CDD:212667	85/413 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900