Protein Alignment CG2918 and hyou1

DIOPT Version :9

• Sequence 1: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_001263614.1
• Gene: hyou1 / 779444
• XenbaseID: XB-GENE-921821
• Length: 985
• Species: Xenopus tropicalis
• Alignment Length: 973
• Identity: 404/973 - (41%)
• Similarity: 585/973 - (60%)
• Gaps: 91/973 - (9%)

  Fly     5 LLLSALLAGIALSQGAAVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRTIG 69
            :.|.|||:  :.::..||||||:||||||:.:|.|||||||.||:||:||||..:|.::..|..|
 Frog    20 MFLLALLS--SNTESVAVMSVDMGSEWMKIAIVKPGVPMEIVLNKESRRKTPVAIALKENERLFG 82

  Fly    70 EDAQTIGIKDPNSAYGYLLDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTVVFRKSDTDEFSVE 134
            :.|..:.:|:|...:.|..|||||..|||.|..:..|||.|.:|.|..|.||:|:.|:...:|.|
 Frog    83 DSALGMAVKNPKVTFRYFQDLLGKRADNPHVKAFEARFPEYQLVKDEHRETVLFKLSEELTYSPE 147

  Fly   135 ELVAQLLVKAKQFAQESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALN 199
            ||:..:|..::..|:|..:||:.:.|:|||.:|.||||.|:|.||||::|||||||||..|||||
 Frog   148 ELLGMMLNYSRSLAEEFAEQPVKDVVITVPAFFNQAERRAVLQAAQLSDLKVLQLINDNTAVALN 212

  Fly   200 YGVFHRGEINETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQ 264
            ||||.|.:||.|||..:||:||:..|...:|:||.||.|.: .:.|.:|:.|||:||||||:|:.
 Frog   213 YGVFRRKDINATAQNIMFYEMGSRSTICTIVTYQSVKTKDS-GMQPQLQIRGVGFDRTLGGIEMD 276

  Fly   265 LRLRDYLAQEFNALKKTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPV 329
            |||||:||:.||..||:|.||..:.||::||.|||.|:|.:||||.:..||||.|::|||||..|
 Frog   277 LRLRDHLAKLFNEQKKSKKDVRENQRAMSKLLKEANRVKTILSANNDHMAQIEGLMDDIDFKAKV 341

  Fly   330 TREKLEQLCEDLWPRATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQE-TIKAVIKQELGKN 393
            ||::||.||.||:.|.:.|::.||:|:.:.::.|:||||.||.||||:||| .:|.|.|:|||||
 Frog   342 TRQELEDLCADLFNRVSAPVQHALSSAEMKMEEIDQVILVGGATRVPKVQELLLKVVGKEELGKN 406

  Fly   394 LNADESATMGAVYKAADLSAGFKVKKFVVKDATLFPLQVSFERDPGD---GAAVKQVKRALFALM 455
            :||||:|.|||||:||.||..||||.|:|:||.:||:||.|.|:..:   ..::|..||.||..:
 Frog   407 INADEAAAMGAVYQAAALSKAFKVKPFIVRDAAIFPIQVEFTREVEEEDHSKSLKHNKRILFQRL 471

  Fly   456 NPYPQKKVITFNKHTDDFEFYVNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELVDN 520
            .||||:||||||::||:|.|.:||.||.....:::...||||:|.|:|..|.|..:  |:...::
 Frog   472 APYPQRKVITFNRYTDNFAFSINYGDLSYLGPDDLKVFGSLNLTTVKLNGVGESFQ--KRSDYES 534

  Fly   521 KGIKAYFYLDDSGIFRCTGVEYVYE---KQKPEDDADEDSTLSKFGSTLSKLF-----TKEGEEK 577
            |||||:|.:|:||:.....||.|:|   .:|||    ::|||:|.|:|:|.||     ..|.:|.
 Frog   535 KGIKAHFNMDESGLLTLDRVEAVFETVVDEKPE----QESTLTKLGNTISSLFGGGSSVPETKEN 595

  Fly   578 KDNSEQEEAANAGEEPSKSEDNEKA-----------------KEEDASKEQK----SEESTKQDT 621
            ..:|.||| .....||:|.|:.|.|                 :||:..||::    .||..||:|
 Frog   596 ATDSVQEE-DEVPTEPTKEEEQESADAADKQKDKEKGTTATNEEEEGKKEEEKSEPQEEKEKQET 659

  Fly   622 EAKNETIKLVTVKSPVTYESQTQFVVPLVG-------------SAYDQSVAKLAAINKAEEQRVR 673
            ..:..:.|...|.:......:.|.:|..:|             ....::..||..:.:.:..:..
 Frog   660 GKEEASAKAPEVDAKKHTAPKKQKLVDDIGVEQTLNDIPDFSEEELKKASKKLQDLTERDLNKHE 724

  Fly   674 LESAFNALEAHIIEVQQKLDEESYAKCATAEEKEKLLAECSTLGEWLYEDLEDPKAEIYEEKLAQ 738
            .|.|.|:|||.|.|.|.||:::.:.:.:|.|::|::.|:.|....||.|:......:..::||::
 Frog   725 REKAANSLEAFIFETQDKLNQDEFKQVSTTEQREEISAKLSQASTWLEEEGYAAITKELKDKLSE 789

  Fly   739 LKKLSNVFLARHWEHEERPEAIKALKGMIDGAEKFLVTGRNLTKDTNPEKD-VFTQVEIDTLDKV 802
            |||:......:..|..:.|:.:.||..:::.:..||.:.|.:     ||.| :||.||:.||:|:
 Frog   790 LKKICKALFFKVEERRKWPDRLAALDSLLNHSSIFLKSARMI-----PEDDQIFTDVELGTLEKL 849

  Fly   803 ITETNAWLKTETAAQKKLAKNADIRLTVKDITDKMSLLDREVKYLVNKIKIWKPKVKPAAEKEKK 867
            |::|..|.....|.|.||:......|..|||..|:..|||||:||:||.|..||       |.||
 Frog   850 ISDTWTWKNETLAEQAKLSLTEKPVLLSKDIEMKIGALDREVQYLLNKAKFSKP-------KPKK 907

  Fly   868 KEEEVVASGSGDDTKSEDAEQQ-----------QEQATKEEQQEQEPVDEITPTPAEEETKTP 919
            |         .:.||.|:||:.           .|::|:|.....|||.|  |..|||:|:.|
 Frog   908 K---------NNTTKPENAEKNATESEEKIIPPTEESTQENASNPEPVKE--PPVAEEKTEIP 959

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	305/635 (48%)
		HYOU1-like_NBD	23..409	CDD:212672	207/386 (54%)
		TAF4	<572..>627	CDD:296797	21/75 (28%)
hyou1	NP_001263614.1	HYOU1-like_NBD	36..422	CDD:212672	207/386 (54%)
		PTZ00121	<602..806	CDD:173412	49/204 (24%)
		SMC_prok_A	<704..950	CDD:274009	83/268 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	564	1.000	Domainoid score	I231
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4658
Inparanoid	1	1.050	681	1.000	Inparanoid score	I705
OMA	1	1.010	-	-		QHG54551
OrthoDB	1	1.010	-	-		D125779at33208
OrthoFinder	1	1.000	-	-		FOG0003505
OrthoInspector	1	1.000	-	-		otm47783
Panther	1	1.100	-	-	LDO	PTHR45639
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3997
SonicParanoid	1	1.000	-	-		X2877
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110