DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2918 and Ankrd45

DIOPT Version :9

Sequence 1:	NP_001162645.1	Gene:	CG2918 / 31215	FlyBaseID:	FBgn0023529	Length:	923	Species:	Drosophila melanogaster
Sequence 2:	XP_030099044.2	Gene:	Ankrd45 / 73844	MGIID:	1921094	Length:	313	Species:	Mus musculus

Alignment Length:	297	Identity:	59/297 - (19%)
Similarity:	100/297 - (33%)	Gaps:	80/297 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   529 LDDSGIFRCTGVE-------YVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGE-EKKDNSEQEE 585
            |.|.|:..|.|..       :..|..:||:..:.:       |:...||:.:.| |:...:|:..
Mouse    37 LRDPGVRGCRGGRHPRYFFFFFLELMEPEETLESE-------SSEKSLFSSQQEYEESQEAEETG 94

  Fly   586 AANAGEEPSKS----------EDNEKAKEEDASKEQKSEESTKQD------TEAKNETIKLVTVK 634
            |.|...:|:.:          ||.|....|.|.:....|:...::      ...|::.||.: .|
Mouse    95 AENPLLQPTLTGDVEGLQKIFEDPEHPHHEHAVQLLLEEDIVGRNLLYAACMAGKSDVIKAL-AK 158

  Fly   635 SPVTYESQTQFVVPLVGSAYDQSVAKLAAINKAEEQR--VRLESAFNALEAHIIEVQQKLDEESY 697
            ..|.....|.....|:..|        ||..:.|..:  |.|:....||.....:.:......|.
Mouse   159 YGVNLNEATARGYTLLHCA--------AAWGRLETLKALVELDVDIEALNFRGEKARDVAARYSQ 215

  Fly   698 AKCAT---------------------------------AEEKEKLLAECSTLGEWLYEDLEDPKA 729
            .:|..                                 .|:|..:|..|....|||....|...:
Mouse   216 VECVNFLDWADARLILKKIITKSSLIITDPEKGPGKLFKEDKSTILNACRLKNEWLESHPEASIS 280

  Fly   730 EIYEEKLAQLKKLSNVFLARHWEHEERPEAIKALKGM 766
            ||:|:| .||:.:.:..||:    ...|..:|:.|.:
Mouse   281 EIFEQK-QQLEDIVSPILAK----MSTPRQVKSAKSI 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	23/119 (19%)
		HYOU1-like_NBD	23..409	CDD:212672
		TAF4	<572..>627	CDD:296797	13/71 (18%)
Ankrd45	XP_030099044.2	Ank_2	123..200	CDD:403870	17/85 (20%)
		ANK repeat	137..167	CDD:293786	5/30 (17%)
		ANK repeat	169..200	CDD:293786	8/38 (21%)
		PTZ00009	<246..300	CDD:240227	16/58 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900