Protein Alignment CG2918 and Hspa12b

DIOPT Version :9

• Sequence 1: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_082582.1
• Gene: Hspa12b / 72630
• MGIID: 1919880
• Length: 685
• Species: Mus musculus
• Alignment Length: 623
• Identity: 121/623 - (19%)
• Similarity: 205/623 - (32%)
• Gaps: 233/623 - (37%)

  Fly   103 YRKRFPYYNIVGDPE--RNTVVFRK------SDTDEFSVEELVA---------QLLVKAKQFAQE 150
            |..|..|:::  |||  |:.:.|.|      |.||.....:|.|         ::...|.:|.:|
Mouse   120 YTARDYYHDL--DPEEARDWLYFEKFKMKIHSATDLTLKTQLEAVNGKKMLALEVFAHALRFFKE 182

  Fly   151 SVQQPI---TEC---------VLTVPGYFGQAEREALLSAAQLANL-------KVLQLINDYAA- 195
            ...|.:   :||         |||||..:.|..::.:..||.||.|       |:|..:...||
Mouse   183 HALQELREQSECMLEKGAVRWVLTVPAIWKQPAKQFMREAAYLAGLVSREDAEKLLIALEPEAAS 247

  Fly   196 -----------VALNYGVFHRGEINETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQV 249
                       :.|:.....||.:.|..         :..:|......||.:.:.:|..  :|:.
Mouse   248 VYCRKLRLHQLMDLSSRTAGRGRLGERR---------SIDSSFRHAREQLRRSRHSRTF--LVEA 301

  Fly   250 LGVGY--------DRTL----GGLEIQLRLRDYLAQEFNALKKTKTDVTTSPRALAKLFKEAGRL 302
             |||.        ||.:    ||..:.|.:.. |.|....||              :|:|.:|..
Mouse   302 -GVGELWAEMQEGDRYMVADCGGGTVDLTVHQ-LEQPHGTLK--------------ELYKASGGP 350

  Fly   303 KNVLSANTEFFAQIENLIEDI---DFKLPVTREKLEQLCEDLW----------PRATKP------ 348
            ...:..:..|    |.|:..|   ||.....|::     ...|          .|...|
Mouse   351 YGAVGVDLAF----EQLLCRIFGEDFIAKFKRQR-----PAAWVDLTIAFEARKRTAGPHRAGAL 406

  Fly   349 -------------------LEEALASS-------------HLSLDVINQVILFGGGTRVPRVQET 381
                               :|.||..|             .:|.:.:|::.           |.|
Mouse   407 NISLPFSFIDFYRKQRGHNVETALRRSSVNLVKWSSQGMLRMSCEAMNELF-----------QPT 460

  Fly   382 IKAVI--------KQEL-GKNL-----NADESATMGAVYKAADLSAGFK------VKKFVVKDAT 426
            :..:|        |.|: |..|     ...|||.:....:.|..:.|.:      |...::|.|.
Mouse   461 VSGIIQHIEMLLAKPEVQGVKLLFLVGGFAESAVLQHAVQEALGTRGLRVVVPHDVGLTILKGAV 525

  Fly   427 LFPLQVSFERDPGDGAAVKQVKRALF----ALMNPY------PQKKVITFNKH--TDDFEFYVNY 479
            ||          |....|.:|:|:..    .::|.:      |:|.::...:.  ||.||.:|
Mouse   526 LF----------GQAPGVVRVRRSPLTYGVGVLNRFVPGHHPPEKLLVRDGRRWCTDVFERFV-- 578

  Fly   480 ADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELVDNKGIKAYF-------YLDDSGIFRC 537
                  :.|:..|||.      ::::........::.::    |..|.       ::.|.|:.:|
Mouse   579 ------AAEQSVALGE------EVRRSYCPARPGQRRVL----INLYCCAAEDARFITDPGVRKC 627

  Fly   538 TGVEYVYEKQK-PEDDADEDS-----TLSKFGSTLSKL 569
            ..:....|.:. ||:.....|     ...:||.|..|:
Mouse   628 GALSLELEPEGCPENTGTSPSRREIRAAMQFGDTEIKV 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	121/623 (19%)
		HYOU1-like_NBD	23..409	CDD:212672	85/430 (20%)
		TAF4	<572..>627	CDD:296797
Hspa12b	NP_082582.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50
		NBD_sugar-kinase_HSP70_actin	61..529	CDD:302596	92/467 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900