Protein Alignment CG2918 and hspa8b

DIOPT Version :9

• Sequence 1: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_001186941.1
• Gene: hspa8b / 562935
• ZFINID: ZDB-GENE-121214-31
• Length: 647
• Species: Danio rerio
• Alignment Length: 754
• Identity: 178/754 - (23%)
• Similarity: 324/754 - (42%)
• Gaps: 159/754 - (21%)

  Fly    16 LSQGAAVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRTIGEDAQTIGIKDP 80
            :|:|.|| .:|||:.:..|||...| .:||..|.:..|.||:.:||.|..|.||:.|:.....:|
Zfish     1 MSKGPAV-GIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNP 63

  Fly    81 NSAYGYLLDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTV-VFRKSDTDEFSVEELVAQLLVKA 144
            .:.......|:|:..|:.:|....|.:| :.::.|..|..| |..|.:|..|..||:.:.:|.|.
Zfish    64 TNTVFDAKRLIGRRFDDAVVQSDMKHWP-FTVINDNLRPKVQVEYKGETKTFYPEEVSSMVLTKM 127

  Fly   145 KQFAQESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYGVFHR--GE 207
            |:.|:..:.:.||..|:|||.||..::|:|...|..::.|.||::||:..|.|:.||:..:  .|
Zfish   128 KEIAEAYLGKTITNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSE 192

  Fly   208 INETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLA 272
            .|     .|.:|:|......::::.:          :.:.:|.....|..|||.:...|:..:..
Zfish   193 RN-----VLIFDLGGGTFDVSILTIE----------DGIFEVKSTAGDTHLGGEDFDNRMVTHFI 242

  Fly   273 QEFNALKKTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQL 337
            .||.  :|.|.|::.:.||:.:|.....|.|..||::|:...:|::|.|.|||...:||.:.|:|
Zfish   243 SEFK--RKYKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEEL 305

  Fly   338 CEDLWPRATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIK-QELGKNLNADESAT 401
            ..||:.....|:|::|..:.|....::.::|.||.||:|::|:.::.... :||.|::|.||:..
Zfish   306 NADLFRGTLDPVEKSLRDAKLDKSQVHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVA 370

  Fly   402 MGAVYKAADLSAGFK---VKKFVVKDATLFPLQVSFERDPGDGAAVKQVKRALFALMNPYPQKKV 463
            .||..:||.| .|.|   |:..::.|.|  ||.:..|...|       |...|.......|.|:.
Zfish   371 YGAAVQAAIL-CGDKSENVQDLLLLDVT--PLSLGIETAGG-------VMTILIKRNTTIPTKQT 425

  Fly   464 ITFNKHTDD-----FEFYVNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELVDNKG- 522
            .||..:.|:     .:.|    :.:|...::...||...:|.:....               :|
Zfish   426 QTFTTYCDNQPGVLIQVY----EGERAMTKDNNLLGKFELTGIPPAP---------------RGV 471

  Fly   523 --IKAYFYLDDSGIFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEEKKDNSEQEE 585
              |:..|.:|.:||...:.|:
Zfish   472 PQIEVTFDIDANGIMNVSAVD-------------------------------------------- 492

  Fly   586 AANAGEEPSKSEDNEKAK--EEDASKEQKSEESTKQDTEAKNETIKLVTVKSPVTYESQTQFVVP 648
             .:.|:|...:..|:|.:  :||..:..:..|..|.:.:.:.|.:
Zfish   493 -KSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQREKV-------------------- 536

  Fly   649 LVGSAYDQSVAKLAAINKAEEQRVRLESAFNALEAHIIEVQQKLDEESYAKCATAEEKEKLLAEC 713
                                       ||.|.||::...::..:::|......:.|:|:|::.:|
Zfish   537 ---------------------------SAKNGLESYSFNMKSTVEDEKLKGKISEEDKQKIINKC 574

  Fly   714 STLGEWLYEDLEDPKAEIYEEKLAQLKKLSNVFLARHWE 752
            :.:..||.::....|.| :|.:..:|:||.|..:.:.::
Zfish   575 NEVISWLDKNQTAEKEE-FEHQQKELEKLCNPIITKLYQ 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	155/619 (25%)
		HYOU1-like_NBD	23..409	CDD:212672	115/389 (30%)
		TAF4	<572..>627	CDD:296797	8/56 (14%)
hspa8b	NP_001186941.1	PTZ00009	1..613	CDD:240227	178/754 (24%)
		HSPA1-2_6-8-like_NBD	6..380	CDD:212675	119/393 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810