Protein Alignment CG2918 and hspa12a.3

DIOPT Version :9

• Sequence 1: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_001038346.3
• Gene: hspa12a.3 / 559031
• ZFINID: ZDB-GENE-030131-8896
• Length: 571
• Species: Danio rerio
• Alignment Length: 636
• Identity: 121/636 - (19%)
• Similarity: 208/636 - (32%)
• Gaps: 211/636 - (33%)

  Fly    54 KTPAILAF--RDGTRTIGEDA-QTIGIKDPNS--AYGYLLDLLGKTIDNPIVDLYRKRFPYYNIV 113
            |||..:.|  .:..:..|.|| .|.....|.|  ...:|.:...       ::||.|..
Zfish    47 KTPTCILFDEHETFQKFGYDAMMTYTRSTPKSQARKSFLFEHFK-------MELYDKEI------ 98

  Fly   114 GDPERNTVVFRKSDTDEFSVEELVAQLLVKAKQFAQESVQQPIT---------ECVLTVPGYFGQ 169
               .|:.::..|:. .:.....:.::.|...|..|.|.:::..|         ..|||||..:..
Zfish    99 ---HRDLMITAKNG-GQMKALTVFSESLRYLKDHALEKIKENTTGKTFIASDVTWVLTVPAIWNA 159

  Fly   170 AEREALLSAAQLANL-------KVLQLINDYAAVALNYGVFHRGEINETA-----------QYFL 216
            |.::.:..||..|.|       :::..:...||......:...|.|:|.|           || :
Zfish   160 AAKQFMREAAIEAGLVIESEPERLVFALEPEAASIYCKQLPSEGYISEEACRDTLEQKPGTQY-M 223

  Fly   217 FYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFN----- 276
            ..|.|.......|  :::|:|.:.:|:|     ...|.|  :||..:..:...:|.:.|:
Zfish   224 VVDCGGGTIDITV--HEVVEDGKLKELN-----AASGND--MGGQTVDRKFISFLKEIFSEKIYN 279

  Fly   277 ---------ALKKTKTDVTTS-----------PRALAKLFKEAGRLKNVLSANTEFFAQIEN--- 318
                     || |.|.|:..:           |..|..|.|:...:::       :|..:|.
Zfish   280 KFEQDFPAEAL-KLKYDIALAKSCDQLVLIQCPVTLQDLAKKEKAIES-------YFEGVEGAEW 336

  Fly   319 ------LIED-----IDFKLPVTREKLEQL-------------------CEDLWPRATKPLEEAL 353
                  :.||     .|..|..|.||||::                   |:.|    .|.|:|..
Zfish   337 DEGSIIIKEDKLQSFFDESLKTTAEKLEKIMSNPELNIEYMLLVGGFAECKIL----KKFLKERF 397

  Fly   354 ASSHLSLDVINQVILFGGGTRVPRVQETIKAVIKQELGKNLNADESATMGAVYKAADLSAGF--- 415
            ....:...|..||::..|..|..:..:.:|                :.|.|:.....:.|.|
Zfish   398 DKCKIVCPVEPQVVIIKGAIRYAKQPKVVK----------------SRMSALTYGIRIDAPFDKV 446

  Fly   416 --KVKKFVVKDATLFPLQVSFERDPGDGAAVK--QVKRALFALMNPYPQKKVITFNKHTDDFEFY 476
              |.|...|.........|.||.....|.:|.  :|::..|   ||...      |:....|:|:
Zfish   447 LHKGKTSYVNSEGQTYCDVCFETFVRKGESVNCDEVRQFFF---NPSDT------NQTFATFQFF 502

  Fly   477 VNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELVDNKGIKAYFYLDDSGIFRCTGVE 541
                              |.|..:||              .:|..|:::.      |:|: .|:
Zfish   503 ------------------STNEKQVQ--------------FIDEPGVESV------GVFQ-VGM- 527

  Fly   542 YVYEKQKPEDDADEDSTLS---KFGSTLSKLFTKEGEEKKDNSEQEEAANA 589
                   |:.|......:.   |||||..|....:.:..:..|.:.:..|:
Zfish   528 -------PKTDGGLSREIKLEIKFGSTEMKATATDVDSGETTSVKLDFINS 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	121/636 (19%)
		HYOU1-like_NBD	23..409	CDD:212672	85/444 (19%)
		TAF4	<572..>627	CDD:296797	2/18 (11%)
hspa12a.3	NP_001038346.3	HSPA12_like_NBD	6..420	CDD:212671	82/411 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900