DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2918 and elp2

DIOPT Version :9

Sequence 1:	NP_001162645.1	Gene:	CG2918 / 31215	FlyBaseID:	FBgn0023529	Length:	923	Species:	Drosophila melanogaster
Sequence 2:	XP_012820102.2	Gene:	elp2 / 548516	XenbaseID:	XB-GENE-5752362	Length:	832	Species:	Xenopus tropicalis

Alignment Length:	388	Identity:	79/388 - (20%)
Similarity:	128/388 - (32%)	Gaps:	127/388 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   532 SGIFRCTGVEYV--YEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEEKKDNSEQEEAANAGEEPS 594
            :||..|.....:  |:.||       :..:|.......::......:|.|.|.:.|..:.|
Frog    34 TGILACATCHSIALYDPQK-------NVVISTLNGHTGRVNCVHWVQKNDCSAETELVSGG---- 87

  Fly   595 KSEDNEKAKEEDASKEQKSEESTKQDTEAKNETIKLVTVKSPVTYESQTQFVVPLVGSAYDQ-SV 658
                ::|.....|.::.|.|:                    ||..|..|: ||..|.:.|.| |.
Frog    88 ----SDKKVIIWAIEKNKCEQ--------------------PVAAEGHTE-VVNAVHAVYTQRSE 127

  Fly   659 AKLAAINKAEEQRVRLESAFNALEAHIIEVQQKLDEESYAKCATAEEKEKLLAECSTLGEWLYED 723
            .:|..::.|.:..|||....|..    .|..|.|   |:.|....:.....|.  .:|...|...
Frog   128 NELLIVSAASDCTVRLWLRRNVK----TECLQTL---SFGKGFVLDVCISFLP--GSLVPVLACG 183

  Fly   724 LEDPKAEIYEEKLAQLKKLSNVFLARHWEHEERPEAIKALKGMIDGAEKFLVTGRNL-------- 780
            .:|.:..:|        .|.|       |..|:.:.:...:..|.|.| :.|||:||
Frog   184 ADDSRIHLY--------VLQN-------EQFEKTQVLHGHEDWIRGVE-WAVTGQNLFLASCAQD 232

  Fly   781 ------------------TKDTN-----------PEKDVFTQVEIDTLDKVIT-ETNA-----WL 810
                              |:|.|           .|||..|...: ||:.|:| ..|:     |
Frog   233 CLIRIWKIFRKTAKENSKTEDENSIKLKENIFKVKEKDTETSYAV-TLETVLTGHENSIYAVHW- 295

  Fly   811 KTETAAQKKLAKNADIRLTVKDITDKMSLLDREV-KYLVNKIKIWKPKVKPAAEKEKKKEEEV 872
                  |...:::.       .|...||||...: |.::    :|:|..:.....|:.:..||
Frog   296 ------QPSFSRDG-------SIVQPMSLLSASMDKTMI----LWEPDEESGVWLEQVRVGEV 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	16/94 (17%)
		HYOU1-like_NBD	23..409	CDD:212672
		TAF4	<572..>627	CDD:296797	9/54 (17%)
elp2	XP_012820102.2	WD40 repeat	28..61	CDD:293791	7/33 (21%)
		WD40	56..419	CDD:238121	73/359 (20%)
		WD40 repeat	67..110	CDD:293791	11/70 (16%)
		WD40 repeat	126..158	CDD:293791	10/38 (26%)
		WD40 repeat	164..206	CDD:293791	9/58 (16%)
		WD40 repeat	212..284	CDD:293791	18/73 (25%)
		WD40 repeat	290..323	CDD:293791	8/50 (16%)
		WD40 repeat	349..388	CDD:293791
		WD40 repeat	395..419	CDD:293791
		WD40 repeat	445..496	CDD:293791
		WD40 repeat	504..548	CDD:293791
		WD40	<563..826	CDD:421866
		WD40 repeat	574..616	CDD:293791
		WD40 repeat	622..672	CDD:293791
		WD40 repeat	677..719	CDD:293791
		WD40 repeat	732..765	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900