DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2918 and CG7182

DIOPT Version :9

Sequence 1:	NP_001162645.1	Gene:	CG2918 / 31215	FlyBaseID:	FBgn0023529	Length:	923	Species:	Drosophila melanogaster
Sequence 2:	NP_001286979.1	Gene:	CG7182 / 38944	FlyBaseID:	FBgn0035878	Length:	513	Species:	Drosophila melanogaster

Alignment Length:	414	Identity:	97/414 - (23%)
Similarity:	172/414 - (41%)	Gaps:	50/414 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRTI--GEDAQTIGIKDPNSAYGYL 87
            :.:|:..:.:..|......|:..|::..|.:.|.|.: ||...|  |..|:......|..|..:.
  Fly     7 IKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLW-DGASEIECGLTAKQKMANRPRQAVAHS 70

  Fly    88 LDLLGKTIDNPIVDLYRKRF--PYYNIVGDPERNTVVFR--------KSDTD-----------EF 131
            ..||     .|..:|..::.  ....|..|.::..:|||        :.|.|           :.
  Fly    71 FQLL-----QPKEELTEEKLSSALREIPCDFDKEELVFRMEHTVPSDREDQDDRVVTKDLSAYQV 130

  Fly   132 SVEELVAQLLVKAKQFAQESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAV 196
            :||.|.|:|.: |.|:..:..|.||  .||::|.|:..:..:.|..|||.|...|.|:|.:..|.
  Fly   131 TVELLRAELEL-AHQYHTDGEQAPI--AVLSIPSYYPASAYKLLADAAQTAGFHVAQIITEPTAA 192

  Fly   197 ALNYGVFHRGEINETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGL 261
            .|.|.:..  |..|..::.|....|...:..|..|.|.....|.....|.          .:||.
  Fly   193 VLGYSIGE--EQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPF----------PIGGR 245

  Fly   262 EIQLRLRDYLAQEFNALKKTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFK 326
            :....|..::.:||.  :|.|.|...|.|::||:...|...|::|:........|::|::.:|:.
  Fly   246 QFTEALVQFICEEFR--RKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYN 308

  Fly   327 LPVTREKLEQLCEDLWPRATKPLEEALASS---HLSLDVINQVILFGGGTRVPRVQETIKAVIKQ 388
            ..::|.:.|.|.:.:.....:.|.|.:..:   |..|..|:.::|.|...::|::|..:.|....
  Fly   309 AQMSRARFESLIQPVINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPD 373

  Fly   389 -ELGKNLNADESATMGAVYKAADL 411
             :|..:.:|||...:|...:|..|
  Fly   374 AKLHNSHSADEVVAIGCARQAVCL 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	97/414 (23%)
		HYOU1-like_NBD	23..409	CDD:212672	95/410 (23%)
		TAF4	<572..>627	CDD:296797
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	95/409 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464182
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830