Protein Alignment CG2918 and SLC9C2

DIOPT Version :9

• Sequence 1: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: XP_011507728.1
• Gene: SLC9C2 / 284525
• HGNCID: 28664
• Length: 1129
• Species: Homo sapiens
• Alignment Length: 578
• Identity: 105/578 - (18%)
• Similarity: 186/578 - (32%)
• Gaps: 208/578 - (35%)

  Fly   110 YNIVGDPERNTVVFRKSDTDEFSV--EELVAQLLVKAKQFAQESVQQPITECVLTVPGYFGQAER 172
            :|::..|:...:..||.:..:..:  .::::.|.:....:......:.:..|||::|       |
Human   384 FNLLWAPDVYNLAERKVEVPQMFILYVQVISLLTMGINSYVMTQSARKLDLCVLSLP-------R 441

  Fly   173 EALLSAAQLANLKVLQLINDYAAVALNYGVFHRGEINETAQYFLFYDMGAYKTSAAV--VSYQLV 235
            :.:|   |.|...:.:::.:...:                          :||...:  |::.||
Human   442 QMIL---QNATQHIQEIVQNTITL--------------------------FKTEKILTNVNWTLV 477

  Fly   236 KDKQTREINP----------------------------VVQVLGVGYDRTLGGLEIQ-LRLRDYL 271
            :||...|..|                            .:|:......|..|.|||: .|:....
Human   478 EDKTRIEYIPFSHVSHNDMKTESTTDEALMEEARLHVAAIQMSSFEKQRNNGILEIEAARILIGA 542

  Fly   272 AQEFNALK---KTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLP----- 328
            |:.:.:::   .:..||:|..|..:.|.|    .||||:.       :|..||.|.|..|
Human   543 AKCYYSIQGKFMSIYDVSTYMRTRSWLIK----FKNVLTF-------LEYCIEKIHFIPPESNTF 596

  Fly   329 -------VTREKLE------------QLCEDLWPRATKPLEEALAS------------SHLSLDV 362
                   |..|:.|            .:...|||.|......||.|            |.|.:.:
Human   597 LTFIFHIVFSEEFEYTGQIINLIYIYPMIIHLWPMARGLNVSALISINYYFMFLYVLESTLKIII 661

  Fly   363 INQ-------------VILFG--------------------------GGTRVPRVQETIKAVI-- 386
            :.:             :::.|                          |..|:.|.....|.::
Human   662 LKRKYFQQCWNTLEFFILVIGIIDIFCVYFVKLRPDNLALIQLTVIMGYLRIIRFLPLFKIIVPI 726

  Fly   387 -----KQELGKNLNADESATMGAVYKAADLSAGFKVKKFVVKDATLFPLQVSFERDPGDGAAVKQ 446
                 ..::.|.|:...|.|.|.:....|  |...:|:..|.::....|....|.:..|  |||:
Human   727 LIRIADVQIKKRLSLMYSITKGYIKSQED--AKLLIKQIAVCESIYQKLCEILETNKQD--AVKE 787

  Fly   447 V-------KRALFALMNPYPQKKVITFNKHTDDFEFYVNYADLDRYSKEEIAALGSLNVTKVQLK 504
            :       :..:.||......:.||.  |...:..|..:...:|   |.|:     :.:.||.||
Human   788 LVLMEHEGRDVVIALKTKQAIRNVIA--KALKNLTFLCSRGIID---KHEV-----IEINKVLLK 842

  Fly   505 QVKEL---------------------LEKSKKELVDNKGIKAYFYLDDSGIFRCTGVE 541
            ::|.|                     || .|..|:|....:|.....|||...|.|.|
Human   843 KLKALNNFPKAIPPPTPDIYLHNIIWLE-GKDVLIDFFKERAKLACFDSGDTICKGGE 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	105/578 (18%)
		HYOU1-like_NBD	23..409	CDD:212672	68/416 (16%)
		TAF4	<572..>627	CDD:296797
SLC9C2	XP_011507728.1	Na_H_Exchanger	98..380	CDD:294713
		Ion_trans	638..>731	CDD:278921	10/92 (11%)
		CAP_ED	873..980	CDD:237999	9/27 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900