Protein Alignment CG2918 and T14G8.3

DIOPT Version :9

• Sequence 1: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_001024913.1
• Gene: T14G8.3 / 181422
• WormBaseID: WBGene00011771
• Length: 921
• Species: Caenorhabditis elegans
• Alignment Length: 964
• Identity: 347/964 - (35%)
• Similarity: 534/964 - (55%)
• Gaps: 103/964 - (10%)

  Fly     1 MKLVLL--LSALLAGIALSQGA----AVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAIL 59
            ||..:|  |..|:|...|.|.|    |.||:||||:::|:|:|.|||||:|.||:||:||||.::
 Worm     1 MKSFILGPLGLLVAICCLYQPADAALAAMSIDLGSQFIKIGLVKPGVPMDIVLNKESRRKTPNVI 65

  Fly    60 AFRDGTRTIGEDAQTIGIKDPNSAYGYLLDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTVVFR 124
            :|::..|...|.|..:....|.|:|.:||.::.:...:.....::|.||:.....|..|.||||.
 Worm    66 SFKNDERFFAEAAAAMSSSHPQSSYNFLLSMIARKEGDDAFVTFQKTFPFTAFEFDEVRKTVVFP 130

  Fly   125 KSDTDEFSVEELVAQLLVKAKQFAQESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQL 189
            ..: ::::||.|:|.:|..||:..:....|.:.:.|:|||.:..||||.|:.|||::|.|.:|||
 Worm   131 YKE-EKYNVETLLAMILWNAKKVTEAYADQTVKDVVITVPIFLNQAERRAIASAAEIAGLNLLQL 194

  Fly   190 INDYAAVALNYGVFHRGEINETAQYFLFYDMGAYKTSAAVVSYQLV------KDKQTREINPVVQ 248
            :||.:|.|||||||.|.||.|...:.|.|||||.||:|.:|.|.|.      ||||     |.::
 Worm   195 LNDGSAAALNYGVFRRKEITEKPTHMLIYDMGAVKTTATIVQYVLESTRKDGKDKQ-----PTLR 254

  Fly   249 VLGVGYDRTLGGLEIQLRLRDYLAQEFNALKKTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFF 313
            .:|||:|:|||||||..||||:|.:.|....||..|::|:.||:.||.|||.|:|.|||||.:.:
 Worm   255 TVGVGFDKTLGGLEITNRLRDHLEKVFRDTVKTSKDISTNARAIGKLHKEAERVKQVLSANKDTY 319

  Fly   314 AQIENLIEDIDFKLPVTREKLEQLCEDLWPRATKPLEEALASSHLSLDVINQVILFGGGTRVPRV 378
            ||:|:|.|:.:|:..||||:||::.|||.||...|:.:|:..:.:|.:.|:.|:|.|.|||||:|
 Worm   320 AQVESLFEEQNFRAKVTREELEKMIEDLEPRIAAPILDAIGMAQISTNDIDLVVLMGAGTRVPKV 384

  Fly   379 QETIKAVIK-QELGKNLNADESATMGAVYKAADLSAGFKVKKFVVKDATLFPLQVSFERDPGDGA 442
            :|.:|.::| :|:...||.||:..|||||:||.||..|||..|.|.:..|:|:.|:|.....:|
 Worm   385 KEILKTILKDKEISNFLNTDEAIAMGAVYQAAHLSKSFKVLPFNVHEKILYPVFVNFLTKTEEG- 448

  Fly   443 AVKQVKRALFALMNPYPQKKVITFNKHTDDFEFYVNYADLDRYSKEEIAALGSLNVTKVQLKQVK 507
            .:|.::::||....|.| .:|:.|:.::|||:..:..||.:..|..||:.             ||
 Worm   449 TMKPIRKSLFGENYPVP-NRVMHFSSYSDDFKIDIQDADKNPLSTVEISG-------------VK 499

  Fly   508 ELLEKSKKELVDN----KGIKAYFYLDDSGIFRCTGVEYVYEK-QKPEDDADEDSTLSKFGSTLS 567
            :.:|   ||:.|.    ||:|..|.:|.|||........|.|| ..||:....:....:|..
 Worm   500 DAIE---KEVTDENSVLKGVKTTFSIDLSGIVSVEKASVVVEKVPTPEEKDKYEVDKKEFDE--- 558

  Fly   568 KLFTKEGEE--KKDNSEQEEAANAGEEPSKSEDNEKAKEEDASKEQKSEESTKQ----------- 619
              :.||.||  ||:.:|::|     :|..|..:.|:.|.|||:.|:|:||.|::
 Worm   559 --WEKEQEELKKKEKAEKKE-----KEEKKKTEGEEEKNEDAAGEEKTEEKTEEVEKPVVVKKTK 616

  Fly   620 --DTEAKNETIKLVTVKSPVTYESQTQFVVPLVGSAYDQSVAKLAAINKA-------EEQRVRLE 675
              :.:||...:.| |:|     |::|..:        |.:..::.|..|.       |:::...|
 Worm   617 PVEPKAKKINVAL-TIK-----ETKTDNI--------DLNEEEVTAAKKVLGDFEQKEKEKHDRE 667

  Fly   676 SAFNALEAHIIEVQQKL-DEESYAKCATAEEKEKLLAECSTLGEWLYEDLE-DPKAEIYEEKLAQ 738
            .|.|.||..:.::..:| |.|.||:.||.|||:.:|.|.:.|..|..:|:. :.|.|.::||.|:
 Worm   668 EAMNRLEGLLYDLAVRLEDGEEYAEYATEEEKKAILEEVAVLKLWFEDDVSLETKKEEFDEKRAK 732

  Fly   739 LKKLSNVFLARHWEHEERPEAIKALKGMIDGAEKFLVTGRNLTKDTNPEKDVFTQVEIDTLDKVI 803
            |::|:....||..|..:.|:..:.::...:.:..|.....|||:.....| .||..|::.|.|:|
 Worm   733 LEELTAKPNARKQERLDIPKVAEIIEDHFNRSMTFHAMALNLTQFEEGNK-TFTDTELEVLTKLI 796

  Fly   804 TETNAWLKTETAAQKKLAKNADIRLTVKDITDKMSLLDREVKYLVNKIKIWKPKVKPAAEKEKKK 868
            ..|..|...:....:|.|||.|..:...:|.:|...|:|||:|||||:||...|....:||:||.
 Worm   797 ESTTEWWNEKKDLFEKQAKNEDPVVKASEIAEKARDLEREVRYLVNKLKIASSKKSKESEKKKKT 861

  Fly   869 EEEVVASGSGDDTKSEDAEQQQEQATKEEQQEQEPVDEITPTPAE-EETKTPHS 921
            ::|       .||..|..|::..:.|.|:|..::.    ||.|.| :.||...|
 Worm   862 KKE-------KDTVKERKEEETTETTTEDQANEQQ----TPPPFENDNTKDDES 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	245/629 (39%)
		HYOU1-like_NBD	23..409	CDD:212672	175/392 (45%)
		TAF4	<572..>627	CDD:296797	22/69 (32%)
T14G8.3	NP_001024913.1	HYOU1-like_NBD	29..416	CDD:212672	175/392 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156802
Domainoid	1	1.000	116	1.000	Domainoid score	I3752
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4658
Inparanoid	1	1.050	508	1.000	Inparanoid score	I716
Isobase	1	0.950	-	0	Normalized mean entropy	S2181
OMA	1	1.010	-	-		QHG54551
OrthoDB	1	1.010	-	-		D125779at33208
OrthoFinder	1	1.000	-	-		FOG0003505
OrthoInspector	1	1.000	-	-		otm14519
orthoMCL	1	0.900	-	-		OOG6_101811
Panther	1	1.100	-	-	LDO	PTHR45639
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2877
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.860