Protein Alignment CG2918 and hsp-70

DIOPT Version :9

• Sequence 1: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_492485.1
• Gene: hsp-70 / 172757
• WormBaseID: WBGene00002026
• Length: 643
• Species: Caenorhabditis elegans
• Alignment Length: 642
• Identity: 171/642 - (26%)
• Similarity: 296/642 - (46%)
• Gaps: 80/642 - (12%)

  Fly    23 MSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRTIGEDAQTIGIKDPNSAYGYL 87
            :.:|||:.:..||:...| .:||..|.|..:.||:.:||.|..|.:|:.|:....::|.:.....
 Worm     7 IGIDLGTTYSCVGIYQNG-KVEILANSEGNKTTPSYVAFTDTERLVGDAAKDQAARNPENTVFDA 70

  Fly    88 LDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTV-VFRKSDTDEFSVEELVAQLLVKAKQFAQES 151
            ..|:|:..|...|....|.:| :.:.|...:..| |..|.:..||:.||:.|.:|.|.|:.|:..
 Worm    71 KRLIGRRFDEETVQSDIKHWP-FTVKGKQGKPVVEVEVKGEKREFNAEEISAMVLQKMKETAEAV 134

  Fly   152 VQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYGVFHRGEINETAQYFL 216
            :...:.:.|:|||.||..::|:|...||.:|.|..:::||:..|.||.||: .:|..:|  :..|
 Worm   135 LGHSVRDAVITVPAYFNDSQRQATKDAATIAGLNAIRIINEPTAAALAYGL-DKGITDE--KNIL 196

  Fly   217 FYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFNALKKT 281
            .:|:|......:::|.         ....:.:|.....|..|||.:...|:..:...||.  :||
 Worm   197 IFDLGGGTFDVSILSI---------AEGSIFEVKSTAGDTHLGGEDFDSRVLQHFMTEFK--RKT 250

  Fly   282 KTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQLCEDLWPRAT 346
            ..|::::|||:.:|.....|.|..||::||...::::|.:..||...:||.:.|:||.||:.:..
 Worm   251 GKDISSNPRAIRRLRTACERAKRTLSSSTEATVEVDSLFDGTDFYSKITRARFEELCADLFRKTL 315

  Fly   347 KPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIK-QELGKNLNADESATMGAVYKAAD 410
            :|:|:||..:......|::|:|.||.||:|::|:.:|.... ::|..::|.||:...||..:||.
 Worm   316 EPVEKALRDAKTDKGRIDEVVLVGGSTRIPKIQKLLKEFFNGKDLNCSINPDEAVAFGAAVQAAV 380

  Fly   411 LSAGFKVKKFVVKDATL---FPLQVSFERDPGDGAAVKQVKRALFALMNPYPQKKVITFNKHTDD 472
            ||.   ||...:||..|   .||....|...|       |...|.......|.|...||..:.|:
 Worm   381 LSG---VKDDTIKDVLLVDVVPLSHGIETAGG-------VMTNLIDRNTRIPAKASKTFTTYADN 435

  Fly   473 -----FEFYVNYADLDRYSKEEIAALGSLNVTKVQ-----LKQVKELLEKSKKELVDNKGIKAYF 527
                 .:.|    :.:|....:...||:..:|.:.     :.||....:      :|..||
 Worm   436 QPGVSIQVY----EGERAMTRDNHRLGTFELTGIPPAPRGVPQVDVTFD------IDANGI---- 486

  Fly   528 YLDDSGIFRCTG----VEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEEKKD---NSEQEE 585
             |:.|...:.||    :....||.: ...||.|..:::     :|.|.:|...::|   :..|.|
 Worm   487 -LNVSAADKSTGRSNRITIRNEKGR-LSQADIDRMVNE-----AKQFEREDAAQRDRISSRNQLE 544

  Fly   586 AANAGEEPSKSEDNEKAKEEDASKEQKSEEST-----------KQDTEAKNETIKLV 631
            |.....:.:..|.......|||.:.:.:.|.|           |.:.|||::.:|.:
 Worm   545 AYAFQVKQALEEHGSLLSAEDAKRAKDAVEDTLRWMERNTLADKDEIEAKDKELKSI 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	169/634 (27%)
		HYOU1-like_NBD	23..409	CDD:212672	114/387 (29%)
		TAF4	<572..>627	CDD:296797	15/68 (22%)
hsp-70	NP_492485.1	PTZ00009	1..643	CDD:240227	171/642 (27%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	116/390 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810