Protein Alignment CG2918 and Hspa9

DIOPT Version :9

• Sequence 1: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: NP_034611.2
• Gene: Hspa9 / 15526
• MGIID: 96245
• Length: 679
• Species: Mus musculus
• Alignment Length: 736
• Identity: 177/736 - (24%)
• Similarity: 302/736 - (41%)
• Gaps: 166/736 - (22%)

  Fly    21 AVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAF-RDGTRTIGEDAQTIGIKDPNSAY 84
            ||:.:|||:....|.|:. |...::..|.|..|.||:::|| .||.|.:|..|:...:.:||:.:
Mouse    54 AVVGIDLGTTNSCVAVME-GKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTF 117

  Fly    85 GYLLDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTVVFRKSDTDE--------FSVEELVAQLL 141
            .....|:|:..|:|.|....|..|:           .:.|.|:.|.        :|..::.|.:|
Mouse   118 YATKRLIGRRYDDPEVQKDTKNVPF-----------KIVRASNGDAWVEAHGKLYSPSQIGAFVL 171

  Fly   142 VKAKQFAQESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYGVFHRG 206
            :|.|:.|:..:.......|:|||.||..::|:|...|.|::.|.||::||:..|.||.||: .:.
Mouse   172 MKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGL-DKS 235

  Fly   207 EINETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYL 271
            |....|    .||:|......:::..|          ..|.:|.....|..|||.:....|..::
Mouse   236 EDKVIA----VYDLGGGTFDISILEIQ----------KGVFEVKSTNGDTFLGGEDFDQALLRHI 286

  Fly   272 AQEFNALKKTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDID----FKLPVTRE 332
            .:||.  ::|..|:|....||.::.:.|.:.|..||::.:....:..|..|..    ..:.:||.
Mouse   287 VKEFK--RETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDASGPKHLNMKLTRA 349

  Fly   333 KLEQLCEDLWPRATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIKQELGKNLNAD 397
            :.|.:..||..|...|.::|:..:.:|...|.:|||.||.||:|:||:|::.:..:...|.:|.|
Mouse   350 QFEGIVTDLIKRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPD 414

  Fly   398 ESATMGAVYKAADLSAGFKVKKFVVKDATLFPLQVSFERDPGDGAAVKQVKRALFALMNPYPQKK 462
            |:..:||..:...|:.  .|...::.|.|  ||.:..|  ...|...|.:.|     ....|.||
Mouse   415 EAVAIGAAIQGGVLAG--DVTDVLLLDVT--PLSLGIE--TLGGVFTKLINR-----NTTIPTKK 468

  Fly   463 VITFNKHTDDFEFYVNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELV-DNK----- 521
            ...|:...|                         ..|:|::|     :.:.::|:. |||
Mouse   469 SQVFSTAAD-------------------------GQTQVEIK-----VCQGEREMAGDNKLLGQF 503

  Fly   522 -------------GIKAYFYLDDSGIFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKE 573
                         .|:..|.:|.:||        |:...|.:....|...:.:....||
Mouse   504 TLIGIPPAPRGVPQIEVTFDIDANGI--------VHVSAKDKGTGREQQIVIQSSGGLS------ 554

  Fly   574 GEEKKDNSEQEEAANAGEEPSKSEDNEKAKEEDASKEQKSE-----ESTKQDTEAKNETIKLVTV 633
                ||:.|           :..::.||..|||..|:::.|     |....|||.|.|..|   .
Mouse   555 ----KDDIE-----------NMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFK---D 601

  Fly   634 KSPVTYESQTQFVVPLVGSAYDQSVAKLAAI--NKAEEQRVRLESAFNALEAHIIEVQQKLDEES 696
            :.|....::.:           :.::|:.|:  .|..|....:..|.::|:    :...||.|.:
Mouse   602 QLPADECNKLK-----------EEISKMRALLAGKDSETGENIRQAASSLQ----QASLKLFEMA 651

  Fly   697 YAKCA----------TAEEKE 707
            |.|.|          |.|:||
Mouse   652 YKKMASEREGSGSSGTGEQKE 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	156/639 (24%)
		HYOU1-like_NBD	23..409	CDD:212672	109/398 (27%)
		TAF4	<572..>627	CDD:296797	15/59 (25%)
Hspa9	NP_034611.2	Interaction with NFS1. /evidence=ECO:0000250|UniProtKB:P38646	1..432		112/408 (27%)
		dnaK	52..673	CDD:234715	177/736 (24%)
		HSPA9-like_NBD	52..428	CDD:212683	111/402 (28%)
		Interaction with FXN and ISCU. /evidence=ECO:0000250|UniProtKB:P38646	432..679		65/327 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	656..679		5/17 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900