Protein Alignment CG2918 and AgaP_AGAP001827

DIOPT Version :9

• Sequence 1: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: XP_321225.3
• Gene: AgaP_AGAP001827 / 1281282
• VectorBaseID: AGAP001827
• Length: 968
• Species: Anopheles gambiae
• Alignment Length: 956
• Identity: 555/956 - (58%)
• Similarity: 694/956 - (72%)
• Gaps: 51/956 - (5%)

  Fly     1 MKLVLLLSALLAGIALSQGAAVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGT 65
            |.|::|...:.....|:..|||||||||||||||||||||||||||||:|||||||..:|||:|.
Mosquito     1 MLLIVLPMVVALFATLANSAAVMSVDLGSEWMKVGVVSPGVPMEIALNKESKRKTPTTIAFRNGD 65

  Fly    66 RTIGEDAQTIGIKDPNSAYGYLLDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTVVFRKSDTDE 130
            |..||||||:|::.|::::|||.||||||:|||:|||||||||||:||.||.|.||||| |..::
Mosquito    66 RVFGEDAQTLGVRFPSNSFGYLTDLLGKTVDNPMVDLYRKRFPYYDIVADPVRRTVVFR-SGEEQ 129

  Fly   131 FSVEELVAQLLVKAKQFAQESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAA 195
            :::|||:||||..||.:|::|..|.||||||.|||::|||||.||::||:|||||||||||||.|
Mosquito   130 YTIEELIAQLLQVAKSYAEDSTGQLITECVLIVPGFYGQAERTALVAAARLANLKVLQLINDYTA 194

  Fly   196 VALNYGVFHRGEINETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGG 260
            ||||||:|.|.||||||||||||||||||||||||||||||||.|||.:||||||||||||||||
Mosquito   195 VALNYGIFRRKEINETAQYFLFYDMGAYKTSAAVVSYQLVKDKATRETHPVVQVLGVGYDRTLGG 259

  Fly   261 LEIQLRLRDYLAQEFNALKKTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDF 325
            ||:|:||||||.:|||.:.||||||.|:|||:|||||||||||||||||||.:||||.|:::.||
Mosquito   260 LEMQVRLRDYLGREFNKMGKTKTDVFTNPRAMAKLFKEAGRLKNVLSANTEHYAQIEGLLDEQDF 324

  Fly   326 KLPVTREKLEQLCEDLWPRATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIKQEL 390
            :|.|.||:.|:||:||:.|.|.||::|||.|.|:|||||||:||||.||||:||:.::..|.|||
Mosquito   325 RLLVKREQFEELCKDLYERVTAPLDKALAVSGLALDVINQVVLFGGNTRVPKVQDILRTHIGQEL 389

  Fly   391 GKNLNADESATMGAVYKAADLSAGFKVKKFVVKDATLFPLQVSFERDPGDGAAVKQVKRALFALM 455
            .|||||||:|.|||||:||||:.|||||||:.|||.|||:||.|:|: |:..|.:||:|.||..|
Mosquito   390 AKNLNADEAACMGAVYRAADLATGFKVKKFITKDAVLFPIQVVFDRE-GESGATRQVRRTLFGSM 453

  Fly   456 NPYPQKKVITFNKHTDDFEFYVNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELVDN 520
            |.||||||||||||||||||.|.||:||...|.:...|||.::.:|||.:|.:.|:.|..|.|::
Mosquito   454 NSYPQKKVITFNKHTDDFEFTVQYAELDAVLKGDTETLGSPDLARVQLSEVAKRLKASVAENVES 518

  Fly   521 KGIKAYFYLDDSGIFRCTGVEYVYEKQKPEDDADED-STLSKFGSTLSKLFT-----KEGEEKKD 579
            |||||:|.|||||||....||.|.||...:::.||| ||..|.|:|:||||:     |..|||..
Mosquito   519 KGIKAHFLLDDSGIFSLANVELVLEKTVTKEEEDEDESTFQKIGNTISKLFSGDSADKPAEEKPP 583

  Fly   580 NSEQEEAANAGEEPSKSEDNEKAKEE--DASKEQKSEESTKQD---------------------- 620
            .....||.:..|..|..|..|.|:||  ...::|:.:|..||.
Mosquito   584 TEGGAEAKDEEEPASGKEGKESAEEEQQQQQQQQQQQEGKKQSGKDKEADGGAKDAKPEAGEPAD 648

  Fly   621 -------TEAKNETI--KLVTVKSPVTYESQTQFVVPLVGSAYDQSVAKLAAINKAEEQRVRLES 676
                   |||||.|:  |:||:|.|:..:.:..:||||.|..:|.|..:|:|:::.::.:.|.|:
Mosquito   649 KKAADEGTEAKNATVKPKIVTLKEPIPSKVELAYVVPLDGELFDASAKRLSALDQVDKAKQRRET 713

  Fly   677 AFNALEAHIIEVQQKLDEESYAKCATAEEKEKLLAECSTLGEWLYEDLEDPKAEIYEEKLAQLKK 741
            |.||||:::|:.|.||||:.||.|||..|.|.:...|..:.||||||..|..||.||.||.:|:.
Mosquito   714 ALNALESYVIDAQVKLDEQEYASCATETEIETIRKRCGEISEWLYEDGSDADAETYETKLEELRG 778

  Fly   742 LSNVFLARHWEHEERPEAIKALKGMIDGAEKFLVTGRNLTKDTNPEKDVFTQVEIDTLDKVITET 806
            ::|...||||||:|||.|:.|||.||:|:|.||.:.|||||||||||||||.|||:||:|.|..|
Mosquito   779 VANEVYARHWEHQERPIALNALKQMINGSEGFLRSARNLTKDTNPEKDVFTAVEIETLEKAIRST 843

  Fly   807 NAWLKTETAAQKKLAKNADIRLTVKDITDKMSLLDREVKYLVNKIKIWKPKVKPAAEKEKKKEEE 871
            ..|..||.|.|:|||:||.:|||||||||:|.||||||||||||:|:|:|||||.   ...|.|:
Mosquito   844 IEWRDTEVAEQEKLARNAPVRLTVKDITDRMGLLDREVKYLVNKLKLWRPKVKPT---PPPKPEK 905

  Fly   872 VVASGSGDDTKSEDAEQQQEQATKEEQQEQEPVDEITPTPAEEETK 917
            ..|.       .::.||::|..:.||....|||.|.||....:||:
Mosquito   906 TTAG-------KKEGEQKEEAPSSEELPGSEPVLEQTPEKDADETE 944

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	399/639 (62%)
		HYOU1-like_NBD	23..409	CDD:212672	283/385 (74%)
		TAF4	<572..>627	CDD:296797	22/85 (26%)
AgaP_AGAP001827	XP_321225.3	HYOU1-like_NBD	23..408	CDD:212672	283/385 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	764	1.000	Domainoid score	I350
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4658
Inparanoid	1	1.050	1046	1.000	Inparanoid score	I832
OMA	1	1.010	-	-		QHG54551
OrthoDB	1	1.010	-	-		D125779at33208
OrthoFinder	1	1.000	-	-		FOG0003505
OrthoInspector	1	1.000	-	-		oto106550
Panther	1	1.100	-	-	LDO	PTHR45639
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2877
TreeFam	1	0.960	-	-
	13	12.940