Protein Alignment CG2918 and AgaP_AGAP004944

DIOPT Version :9

• Sequence 1: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: XP_315042.3
• Gene: AgaP_AGAP004944 / 1275756
• VectorBaseID: AGAP004944
• Length: 647
• Species: Anopheles gambiae
• Alignment Length: 740
• Identity: 169/740 - (22%)
• Similarity: 310/740 - (41%)
• Gaps: 144/740 - (19%)

  Fly    23 MSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRTIGEDAQTIGIKDPNSAYGYL 87
            :.:|||:.:..|||...| .::|..|.:..|.||:.:||.|..|.||:.|:.....:||:.....
Mosquito     7 VGIDLGTTYSCVGVFQHG-KVDIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPNNTIFDA 70

  Fly    88 LDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTV-VFRKSDTDEFSVEELVAQLLVKAKQFAQES 151
            ..|:|:..|:..|....|.:| ::::.|..:..: |..|.:...|..||:.:.:|.|.|:.|:..
Mosquito    71 KRLIGRKFDDATVQADMKHWP-FDVISDGGKPKLQVEYKGEKKSFFPEEVSSMVLTKMKETAEAY 134

  Fly   152 VQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYGVFHR--GEINETAQY 214
            :.:.|...|:|||.||..::|:|...|..:|.|.||::||:..|.|:.||:..:  ||.|
Mosquito   135 LGKSIANAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKKGAGERN----- 194

  Fly   215 FLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFNALK 279
            .|.:|:|......::::.:          :.:.:|.....|..|||.:...|:..:..:||.  :
Mosquito   195 VLIFDLGGGTFDVSILTIE----------DGIFEVKSTAGDTHLGGEDFDNRMVSHFVEEFK--R 247

  Fly   280 KTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQLCEDLWPR 344
            |.|.|:|::.|||.:|.....|.|..|||:|:...:|::|.|.|||...:||.:.|:|..||:..
Mosquito   248 KHKKDITSNKRALRRLRTACERAKRTLSASTQASIEIDSLYEGIDFYTSITRARFEELNSDLFRD 312

  Fly   345 ATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIK-QELGKNLNADESATMGAVYKA 408
            ..:|:.:||..:.:....|:.::|.||.||:|:||:.::.... :||.|::|.||:...||..:|
Mosquito   313 TMEPVSKALRDAKMDKASIHDIVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQA 377

  Fly   409 ADLSAGFK--VKKFVVKDATLFPLQVSFERDPGDGAAVKQVKRALFALMNPYPQKKVITFNKHTD 471
            |.|.....  |:..::.|.|  ||.:..|...|       |...|.......|.|:..||..::|
Mosquito   378 AILQGDTSEAVQDLLLLDVT--PLSLGIETAGG-------VMTVLIKRNTTIPTKQTQTFTTYSD 433

  Fly   472 DFE-FYVNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELVDNKG---IKAYFYLDDS 532
            :.. ..:...:.:|...::...||...::.:....               :|   |:..|.:|.:
Mosquito   434 NQPGVLIQVFEGERAMTKDNNLLGKFELSGIPPAP---------------RGVPQIEVTFDIDAN 483

  Fly   533 GIFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEEKKDNSEQEEAANAGEEPSKSE 597
            ||...:.:                                   ||..|.|.....        :.
Mosquito   484 GIMNVSAI-----------------------------------EKSTNKENRITI--------TN 505

  Fly   598 DNEKAKEEDASKEQKSEESTKQDTEAKNETIKLVTVKSPVTYESQTQFVVPLVGSAYDQSVAKLA 662
            |..:..:||..:.....|..:.:.|.:.|.|
Mosquito   506 DKGRLSKEDIDRMVNEAEKFRNEDEKQREKI---------------------------------- 536

  Fly   663 AINKAEEQRVRLESAFNALEAHIIEVQQKLDEESYAKCATAEEKEKLLAECSTLGEWLYEDLEDP 727
                         ||.|:|||:...::..:::.:........:|..::.:|:....|| :..:..
Mosquito   537 -------------SAKNSLEAYCFNMKSTMEDANIKDKIPDADKTLIMDKCNATIAWL-DGNQTA 587

  Fly   728 KAEIYEEKLAQLKKLSNVFLARHWE 752
            :.|.:|.|..:|:.:.|..:.:.::
Mosquito   588 EKEEFEHKQKELEAVCNPIIQKLYQ 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	152/611 (25%)
		HYOU1-like_NBD	23..409	CDD:212672	117/389 (30%)
		TAF4	<572..>627	CDD:296797	9/54 (17%)
AgaP_AGAP004944	XP_315042.3	PTZ00009	1..647	CDD:240227	169/740 (23%)
		HSPA1-2_6-8-like_NBD	6..380	CDD:212675	119/391 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810