Protein Alignment Grp170 and LOC1275756

DIOPT Version :10

• Sequence 1: NP_569995.1
• Gene: Grp170 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: XP_315042.3
• Gene: LOC1275756 / 1275756
• VectorBaseID: AGAMI1_000862
• Length: 647
• Species: Anopheles gambiae
• Alignment Length: 739
• Identity: 169/739 - (22%)
• Similarity: 311/739 - (42%)
• Gaps: 142/739 - (19%)

  Fly    23 MSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRTIGEDAQTIGIKDPNSAYGYL 87
            :.:|||:.:..|||...| .::|..|.:..|.||:.:||.|..|.||:.|:.....:||:.....
Mosquito     7 VGIDLGTTYSCVGVFQHG-KVDIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPNNTIFDA 70

  Fly    88 LDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTV-VFRKSDTDEFSVEELVAQLLVKAKQFAQES 151
            ..|:|:..|:..|....|.:| ::::.|..:..: |..|.:...|..||:.:.:|.|.|:.|:..
Mosquito    71 KRLIGRKFDDATVQADMKHWP-FDVISDGGKPKLQVEYKGEKKSFFPEEVSSMVLTKMKETAEAY 134

  Fly   152 VQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYGVFHR--GEINETAQY 214
            :.:.|...|:|||.||..::|:|...|..:|.|.||::||:..|.|:.||:..:  ||.|
Mosquito   135 LGKSIANAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKKGAGERN----- 194

  Fly   215 FLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFNALK 279
            .|.:|:|......::::.:          :.:.:|.....|..|||.:...|:..:..:||.  :
Mosquito   195 VLIFDLGGGTFDVSILTIE----------DGIFEVKSTAGDTHLGGEDFDNRMVSHFVEEFK--R 247

  Fly   280 KTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQLCEDLWPR 344
            |.|.|:|::.|||.:|.....|.|..|||:|:...:|::|.|.|||...:||.:.|:|..||:..
Mosquito   248 KHKKDITSNKRALRRLRTACERAKRTLSASTQASIEIDSLYEGIDFYTSITRARFEELNSDLFRD 312

  Fly   345 ATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIK-QELGKNLNADESATMGAVYKA 408
            ..:|:.:||..:.:....|:.::|.||.||:|:||:.::.... :||.|::|.||:...||..:|
Mosquito   313 TMEPVSKALRDAKMDKASIHDIVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQA 377

  Fly   409 ADLSAGFK--VKKFVVKDATLFPLQVSFERDPGDGAAVKQVKRALFALMNPYPQKKVITFNKHTD 471
            |.|.....  |:..::.|.|  ||.:..|...|       |...|.......|.|:..||..::|
Mosquito   378 AILQGDTSEAVQDLLLLDVT--PLSLGIETAGG-------VMTVLIKRNTTIPTKQTQTFTTYSD 433

  Fly   472 DFE-FYVNYADLDRYSKEEIAALGSLNVTKV--QLKQVKELLEKSKKELVDNKGIKAYFYLDDSG 533
            :.. ..:...:.:|...::...||...::.:  ..:.|.:              |:..|.:|.:|
Mosquito   434 NQPGVLIQVFEGERAMTKDNNLLGKFELSGIPPAPRGVPQ--------------IEVTFDIDANG 484

  Fly   534 IFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEEKKDNSEQEEAANAGEEPSKSED 598
            |...:.:                                   ||..|.|.....        :.|
Mosquito   485 IMNVSAI-----------------------------------EKSTNKENRITI--------TND 506

  Fly   599 NEKAKEEDASKEQKSEESTKQDTEAKNETIKLVTVKSPVTYESQTQFVVPLVGSAYDQSVAKLAA 663
            ..:..:||..:.....|..:.:.|.:.|.|
Mosquito   507 KGRLSKEDIDRMVNEAEKFRNEDEKQREKI----------------------------------- 536

  Fly   664 INKAEEQRVRLESAFNALEAHIIEVQQKLDEESYAKCATAEEKEKLLAECSTLGEWLYEDLEDPK 728
                        ||.|:|||:...::..:::.:........:|..::.:|:....|| :..:..:
Mosquito   537 ------------SAKNSLEAYCFNMKSTMEDANIKDKIPDADKTLIMDKCNATIAWL-DGNQTAE 588

  Fly   729 AEIYEEKLAQLKKLSNVFLARHWE 752
            .|.:|.|..:|:.:.|..:.:.::
Mosquito   589 KEEFEHKQKELEAVCNPIIQKLYQ 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grp170	NP_569995.1	ASKHA_NBD_HSP70_HYOU1	21..409	CDD:466828	117/389 (30%)
		PTZ00121	<546..917	CDD:173412	26/207 (13%)
		TAF4	<572..>627	CDD:461598	9/54 (17%)
LOC1275756	XP_315042.3	PTZ00009	1..647	CDD:240227	169/739 (23%)