Protein Alignment CG2918 and AgaP_AGAP004192

DIOPT Version :9

• Sequence 1: NP_001162645.1
• Gene: CG2918 / 31215
• FlyBaseID: FBgn0023529
• Length: 923
• Species: Drosophila melanogaster
• Sequence 2: XP_313085.3
• Gene: AgaP_AGAP004192 / 1274027
• VectorBaseID: AGAP004192
• Length: 659
• Species: Anopheles gambiae
• Alignment Length: 697
• Identity: 184/697 - (26%)
• Similarity: 306/697 - (43%)
• Gaps: 97/697 - (13%)

  Fly     1 MKLV--LLLSALLAGIALSQG---------AAVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRK 54
            |||:  ..|..:||.:|.|..         ..|:.:|||:.:..|||...| .:||..|.:..|.
Mosquito     1 MKLLKQTALVVVLAVLACSAEEKKEKDKDIGTVVGIDLGTTYSCVGVYKNG-RVEIIANDQGNRI 64

  Fly    55 TPAILAF-RDGTRTIGEDAQTIGIKDPNSAYGYLLDLLGKTIDNPIVDLYRKRFPYYNIVGDPER 118
            ||:.:|| .||.|.||:.|:.....:|.:.......|:|:...:..|....|..|:..|    |:
Mosquito    65 TPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREFTDHTVQHDIKLLPFKVI----EK 125

  Fly   119 NTVVFRKSDTDE----FSVEELVAQLLVKAKQFAQESVQQPITECVLTVPGYFGQAEREALLSAA 179
            |:....:..|.:    |:.||:.|.:|.|.|:.|:..:.:.:|..|:|||.||..|:|:|...|.
Mosquito   126 NSKPHIRVSTGQGDKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAG 190

  Fly   180 QLANLKVLQLINDYAAVALNYGVFHR-GEINETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREI 243
            .:|.|.|:::||:..|.|:.||:..: ||.|     .|.:|:|......::::..
Mosquito   191 TIAGLVVMRIINEPTAAAIAYGLDKKDGEKN-----VLVFDLGGGTFDVSLLTID---------- 240

  Fly   244 NPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFNALKKTKTDVTTSPRALAKLFKEAGRLKNVLSA 308
            |.|.:|:....|..|||.:...|:.|:..:.:.  ||...|:....||:.||.:|..:.|..|||
Mosquito   241 NGVFEVVATNGDTHLGGEDFDQRVMDHFIKMYK--KKKGKDIRKDNRAVQKLRREVEKAKRALSA 303

  Fly   309 NTEFFAQIENLIEDIDFKLPVTREKLEQLCEDLWPRATKPLEEALASSHLSLDVINQVILFGGGT 373
            :.:...:||:..|..||...:||.|.|:|..||:....||:.:.|..:.::.:.:::::|.||.|
Mosquito   304 SHQVRIEIESFFEGDDFSETLTRAKFEELNMDLFRSTMKPVHKVLEDADMTKNDVDEIVLVGGST 368

  Fly   374 RVPRVQETIKAVIK-QELGKNLNADESATMGAVYKAADLSAGFKVKKFVVKDATLFPLQVSFERD 437
            |:|:||:.:|.... :|..:.:|.||:...||..:|..||........|:.|..  ||.:..|
Mosquito   369 RIPKVQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDAIVLLDVN--PLTMGIE-- 429

  Fly   438 PGDGAAVKQVKRALFALMNPYPQKKVITF-----NKHTDDFEFYVNYADLDRYSKEEIAALGSLN 497
                 .|..|...|.......|.||...|     |:||...:.|    :.:|...::...||..:
Mosquito   430 -----TVGGVMTKLIPRNTVIPTKKSQIFSTASDNQHTVTIQVY----EGERPMTKDNHLLGKFD 485

  Fly   498 VTKVQ-----LKQVKELLEKSKKELVDNKGIKAYFYLDDSGIFRCTGVEYVYEKQK--PEDDADE 555
            :|.:.     :.|::...|      :|..|| .....:|.|......:....::.:  |:|....
Mosquito   486 LTGIPPAPRGIPQIEVSFE------IDANGI-LQVSAEDKGTGNREKIVITNDQNRLTPDDIERM 543

  Fly   556 DSTLSKFGSTLSKLFTKEGEEKKDNSEQEEAANAGEEPSKSE------DNEKAKEEDASKEQKSE 614
            .....:|.....||  ||..|.::..|....:...:..||.:      |::|||.|:|..|:...
Mosquito   544 IKDAERFADDDKKL--KERVEARNELESYAYSLKNQLSSKDKLGASVSDDDKAKMEEAIDEKIKW 606

  Fly   615 ESTKQDTEAKNETIKLVTVKSPVTYESQTQ----FVVPLVGSAYDQS 657
            ....|||||:.             |:.|.:    .|.|::...|..|
Mosquito   607 LDENQDTEAEE-------------YKKQKKELEDIVQPIIAKLYASS 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2918	NP_001162645.1	HSP70	22..625	CDD:278441	170/627 (27%)
		HYOU1-like_NBD	23..409	CDD:212672	116/392 (30%)
		TAF4	<572..>627	CDD:296797	18/60 (30%)
AgaP_AGAP004192	XP_313085.3	HSPA5-like_NBD	31..405	CDD:212681	117/395 (30%)
		PTZ00009	34..645	CDD:240227	175/664 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810