DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2924 and Ube2q1

DIOPT Version :9

Sequence 1:	NP_001284819.1	Gene:	CG2924 / 31214	FlyBaseID:	FBgn0023528	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_081591.3	Gene:	Ube2q1 / 70093	MGIID:	1917343	Length:	422	Species:	Mus musculus

Alignment Length:	417	Identity:	208/417 - (49%)
Similarity:	274/417 - (65%)	Gaps:	61/417 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LKQEIKTLEKIFPKNHERFQILNSSVDELLCRFI---------------------DKNGKRYDIH 50
            |::|:|.||.||.:.||||:|.::.:|||.|.|:                     ...|....||
Mouse    41 LRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPSRGSVPGDPVRIH 105

  Fly    51 ANITETYPSSPPVWFAESEETSVTNAVQILSNTNGRDNHVINQVGILLRELCRLHNVPLPPDIDN 115
            .||||:||:.||:|..||::.::...::.|.:....:..::..:..::.:||:|:|:|..||::.
Mouse   106 CNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEM 170

  Fly   116 LALPLQTPPPSASPLRCEQRPGGGGAGGGGGPHGNEETDSDQEEIEDPIGESEQESEGDEDLP-L 179
            |..||...       :|.|                ||..|:.|:.|.|        |..|||. .
Mouse   171 LDQPLPAE-------QCTQ----------------EEVSSEDEDEEMP--------EDTEDLDHY 204

  Fly   180 EMDDVR----STSKKDDMEVEHLATLEKLRQSQRQDYLKGSVSGSVQATDRLMKELRDIYRSDAF 240
            ||.:..    ..|:.|.:..|:||.|||::::||||||.|:|||||||||||||||||||||.:|
Mouse   205 EMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSF 269

  Fly   241 KKNMYSIELVNESIYEWNIRLKSVDPDSPLHSDLQMLKEKEGKDSILLNILFKETYPFEPPFVRV 305
            |...|::||||:|:|:||::|..||.||.||:|||:||||||.|.||||..||:.:||:||||||
Mouse   270 KGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRV 334

  Fly   306 VHPIISGGYVLIGGAICMELLTKQGWSSAYTVEAVIMQIAATLVKGKARIQFGATKALTQGQYSL 370
            |.|::||||||.||||||||||||||||||::|:|||||:|||||||||:||||.|:    ||||
Mouse   335 VSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKS----QYSL 395

  Fly   371 ARAQQSFKSLVQIHEKNGWFTPPKEDG 397
            .|||||:||||||||||||:|||||||
Mouse   396 TRAQQSYKSLVQIHEKNGWYTPPKEDG 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2924	NP_001284819.1	UBCc	224..>349	CDD:238117	90/124 (73%)
Ube2q1	NP_081591.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..40
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..221		17/78 (22%)
		UBCc	253..409	CDD:238117	116/159 (73%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	210	1.000	Domainoid score	I2815
eggNOG	1	0.900	-	-		E1_KOG0897
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	388	1.000	Inparanoid score	I1994
Isobase	1	0.950	-	0	Normalized mean entropy	S1963
OMA	1	1.010	-	-		QHG49199
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003048
OrthoInspector	1	1.000	-	-		otm43422
orthoMCL	1	0.900	-	-		OOG6_104870
Panther	1	1.100	-	-	O	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4130
SonicParanoid	1	1.000	-	-		X2030
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.810