DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2924 and ube2q2

DIOPT Version :9

Sequence 1:	NP_001284819.1	Gene:	CG2924 / 31214	FlyBaseID:	FBgn0023528	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001006696.1	Gene:	ube2q2 / 448322	XenbaseID:	XB-GENE-5858741	Length:	368	Species:	Xenopus tropicalis

Alignment Length:	394	Identity:	212/394 - (53%)
Similarity:	283/394 - (71%)	Gaps:	34/394 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LKQEIKTLEKIFPKNHERFQILNSSVDELLCRFIDKNGKRYDIHANITETYPSSPPVWFAESEET 71
            ||.|::.||.||.|.||||:|::..:|||.|.||...|....||.||||:||||.|:||.||::.
Frog     6 LKAELRLLESIFGKEHERFRIVSWRLDELHCVFIQSTGGALTIHCNITESYPSSAPIWFVESDDP 70

  Fly    72 SVTNAVQILSNTNGRDNHVINQVGILLRELCRLHNVPLPPDIDNLALPLQTPPPSASPLRCEQRP 136
            ::|:.::.|.:....:..::.|:..|:.:||||:|:|..||::.|..||.|
Frog    71 NLTSVLERLEDIKKSNTLLLQQLKRLICDLCRLYNLPQHPDVEMLDQPLPT-------------- 121

  Fly   137 GGGGAGGGGGPHGNEETDSDQEEIEDPIGESEQESEG---DEDLPLEMDDVRSTSKKDDMEVEHL 198
                     |.:|..|..:.:||.|:.:||..::.:.   .|:.|::    ...|:.:.:|.|:|
Frog   122 ---------GQNGTTEEVTSEEEEEEDMGEDIEDLDHYDMKEEEPVD----GKKSEDEGIEKENL 173

  Fly   199 ATLEKLRQSQRQDYLKGSVSGSVQATDRLMKELRDIYRSDAFKKNMYSIELVNESIYEWNIRLKS 263
            |.|||:|::||||:|.|:|||||||:|||||||||||||.::|..:||:||||:|:|||:::|..
Frog   174 AILEKIRKNQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELVNDSLYEWHVKLLK 238

  Fly   264 VDPDSPLHSDLQMLKEKEGKDSILLNILFKETYPFEPPFVRVVHPIISGGYVLIGGAICMELLTK 328
            |||||||||||.:||||||.:.||||..||:.:||:|||||||.|::||||||.|||:|||||||
Frog   239 VDPDSPLHSDLLVLKEKEGVECILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGALCMELLTK 303

  Fly   329 QGWSSAYTVEAVIMQIAATLVKGKARIQFGATKALTQGQYSLARAQQSFKSLVQIHEKNGWFTPP 393
            |||||||::|:|||||.|||||||||:||||.|    .||:|||||||:||||||||||||:|||
Frog   304 QGWSSAYSIESVIMQINATLVKGKARVQFGANK----NQYNLARAQQSYKSLVQIHEKNGWYTPP 364

  Fly   394 KEDG 397
            ||||
Frog   365 KEDG 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2924	NP_001284819.1	UBCc	224..>349	CDD:238117	89/124 (72%)
ube2q2	NP_001006696.1	RWD	9..106	CDD:383087	41/96 (43%)
ube2q2	NP_001006696.1	UBCc	199..355	CDD:238117	115/159 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	149	1.000	Domainoid score	I4415
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H45455
Inparanoid	1	1.050	414	1.000	Inparanoid score	I1794
OMA	1	1.010	-	-		QHG49199
OrthoDB	1	1.010	-	-		D1214134at2759
OrthoFinder	1	1.000	-	-		FOG0003048
OrthoInspector	1	1.000	-	-		oto103859
Panther	1	1.100	-	-	LDO	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4130
SonicParanoid	1	1.000	-	-		X2030
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110