DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2924 and ube2q2

DIOPT Version :9

Sequence 1:	NP_001284819.1	Gene:	CG2924 / 31214	FlyBaseID:	FBgn0023528	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001315128.1	Gene:	ube2q2 / 406260	ZFINID:	ZDB-GENE-040426-1919	Length:	379	Species:	Danio rerio

Alignment Length:	398	Identity:	215/398 - (54%)
Similarity:	290/398 - (72%)	Gaps:	31/398 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LKQEIKTLEKIFPKNHERFQILNSSVDELLCRFIDKNGKRYDIHANITETYPSSPPVWFAESEET 71
            ||.|:|.||.||..|||||:|::...|||.|:|.....|...||.||||:|||:||:||.:|::.
Zfish     6 LKAELKFLESIFDPNHERFRIIDWKPDELSCQFNVTGEKLLIIHCNITESYPSTPPIWFVDSDDP 70

  Fly    72 SVTNAVQILSNTNGRDNHVINQVGILLRELCRLHNVPLPPDIDNLALPLQTPPPSASPLRCEQRP 136
            |:|..::.|.:....:..::.|:..|:.:||||:|:|..||::.|..||     .|.|:..:::
Zfish    71 SLTEVLERLEDVRKGNALLLQQLKRLICDLCRLYNLPQHPDVEMLDQPL-----PAGPISNDKK- 129

  Fly   137 GGGGAGGGGGPHG-NEETDSDQEEIEDPIGESEQESEGDEDLPLEMDDVRSTSKKDD-MEVEHLA 199
                       || .:|..|::||.|:   .:||:.|..:...::.:.|.....:|| :|.|:||
Zfish   130 -----------HGTTDEVTSEEEEEEE---MAEQDIEDLDHYEMKEEPVDGKKSEDDGIEKENLA 180

  Fly   200 TLEKLRQSQRQDYL-----KGSVSGSVQATDRLMKELRDIYRSDAFKKNMYSIELVNESIYEWNI 259
            .|||:|::||||:|     .|:|||||||:||||||||:||||.::|..:||:||||:|:|||::
Zfish   181 ILEKIRKNQRQDHLNVSVHSGAVSGSVQASDRLMKELREIYRSQSYKTGIYSVELVNDSLYEWHV 245

  Fly   260 RLKSVDPDSPLHSDLQMLKEKEGKDSILLNILFKETYPFEPPFVRVVHPIISGGYVLIGGAICME 324
            :|::||||||||||||:||||||.|.||||..:|:.:||:|||||||.|::||||||.|||:|||
Zfish   246 KLRTVDPDSPLHSDLQVLKEKEGMDYILLNFSYKDNFPFDPPFVRVVSPVLSGGYVLGGGALCME 310

  Fly   325 LLTKQGWSSAYTVEAVIMQIAATLVKGKARIQFGATKALTQGQYSLARAQQSFKSLVQIHEKNGW 389
            |||||||||||::|:|||||.|||||||||:||||.|    .||:|||||||:||||||||||||
Zfish   311 LLTKQGWSSAYSIESVIMQINATLVKGKARVQFGANK----NQYNLARAQQSYKSLVQIHEKNGW 371

  Fly   390 FTPPKEDG 397
            :|||||||
Zfish   372 YTPPKEDG 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2924	NP_001284819.1	UBCc	224..>349	CDD:238117	89/124 (72%)
ube2q2	NP_001315128.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	228	1.000	Domainoid score	I2424
eggNOG	1	0.900	-	-		E1_KOG0897
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	413	1.000	Inparanoid score	I1814
OMA	1	1.010	-	-		QHG49199
OrthoDB	1	1.010	-	-		D1214134at2759
OrthoFinder	1	1.000	-	-		FOG0003048
OrthoInspector	1	1.000	-	-		otm26604
orthoMCL	1	0.900	-	-		OOG6_104870
Panther	1	1.100	-	-	LDO	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4130
SonicParanoid	1	1.000	-	-		X2030
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870