DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2924 and Ube2q2

DIOPT Version :9

Sequence 1:	NP_001284819.1	Gene:	CG2924 / 31214	FlyBaseID:	FBgn0023528	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_850931.2	Gene:	Ube2q2 / 109161	MGIID:	2388672	Length:	378	Species:	Mus musculus

Alignment Length:	407	Identity:	207/407 - (50%)
Similarity:	281/407 - (69%)	Gaps:	50/407 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LKQEIKTLEKIFPKNHERFQILNSSVDELLCRFI-----DKNGKRYD------IHANITETYPSS 60
            ||.|:|.|..||.||||||:|::..:|||.|:|:     ...|....      :|.||||:||||
Mouse     6 LKAELKFLASIFDKNHERFRIVSWKLDELHCQFLVPPPPPPPGSSLSPPPPLTLHCNITESYPSS 70

  Fly    61 PPVWFAESEETSVTNAVQILSNTNGRDNHVINQVGILLRELCRLHNVPLPPDIDNLALPLQTPPP 125
            .|:||.:|::.::|:.::.|.:|. .::.:..|:..|:.:||||:|:|...|::.|..||.|
Mouse    71 SPIWFVDSDDPNLTSVLERLEDTK-NNSSLRQQLKWLICDLCRLYNLPKHLDVEMLDQPLPT--- 131

  Fly   126 SASPLRCEQRPGGGGAGGGGGPHGNEETDSDQEEIEDPIGESEQESEGDEDLP----LEMDDVRS 186
                                |.:|..|..:.:||      |.|:.:|..|||.    .|.:.:..
Mouse   132 --------------------GQNGTTEEVTSEEE------EEEEMAEDIEDLDHYEMKEEEPING 170

  Fly   187 TSKKDD-MEVEHLATLEKLRQSQRQDYLKGSVSGSVQATDRLMKELRDIYRSDAFKKNMYSIELV 250
            ...:|: :|.|:||.|||:|::||||:|.|:|||||||:|||||||||:|||.::|..:||:||:
Mouse   171 KKSEDEGIEKENLAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDVYRSQSYKAGIYSVELI 235

  Fly   251 NESIYEWNIRLKSVDPDSPLHSDLQMLKEKEGKDSILLNILFKETYPFEPPFVRVVHPIISGGYV 315
            |:|:|:|:::|..||.|||||||||:||||||.:.||||..||:.:||:|||||||.|::|||||
Mouse   236 NDSLYDWHVKLHKVDSDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGYV 300

  Fly   316 LIGGAICMELLTKQGWSSAYTVEAVIMQIAATLVKGKARIQFGATKALTQGQYSLARAQQSFKSL 380
            |.|||:||||||||||||||::|:|||||.|||||||||:||||.|    .||:|||||||:.|:
Mouse   301 LGGGALCMELLTKQGWSSAYSIESVIMQINATLVKGKARVQFGANK----NQYNLARAQQSYNSI 361

  Fly   381 VQIHEKNGWFTPPKEDG 397
            |||||||||:|||||||
Mouse   362 VQIHEKNGWYTPPKEDG 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2924	NP_001284819.1	UBCc	224..>349	CDD:238117	86/124 (69%)
Ube2q2	NP_850931.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	126..152		10/54 (19%)
Ube2q2	NP_850931.2	UBCc	209..365	CDD:294101	110/159 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	210	1.000	Domainoid score	I2815
eggNOG	1	0.900	-	-		E1_KOG0897
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H45455
Inparanoid	1	1.050	388	1.000	Inparanoid score	I1994
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49199
OrthoDB	1	1.010	-	-		D1214134at2759
OrthoFinder	1	1.000	-	-		FOG0003048
OrthoInspector	1	1.000	-	-		otm43422
orthoMCL	1	0.900	-	-		OOG6_104870
Panther	1	1.100	-	-	LDO	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4130
SonicParanoid	1	1.000	-	-		X2030
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.870