Protein Alignment CG3071 and UTP15

DIOPT Version :10

• Sequence 1: NP_569993.1
• Gene: CG3071 / 31213
• FlyBaseID: FBgn0023527
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_115551.2
• Gene: UTP15 / 84135
• HGNCID: 25758
• Length: 518
• Species: Homo sapiens
• Alignment Length: 477
• Identity: 188/477 - (39%)
• Similarity: 282/477 - (59%)
• Gaps: 6/477 - (1%)

  Fly    21 TPDTVYWDRLAKPELLKEHNTIDYLDFSPSDPDNFVVTCSVRVQIYNLVTMLVVKNLSRFQKTAY 85
            |.||:||:....|..:||...:..:||||..|.|:.||.|.|:.||...:...:|..|||:.|||
Human    20 TQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAY 84

  Fly    86 GATFRQDGRLLAAGDEEGHVKLFDTTSRNILRLFKGHTAPVHRTFFTADKLQLASFGDDKSVRLW 150
            .||||||||||.||.|:|.|:|||.:.|..||.|:|||..||...|||||..:.|..||.:|:||
Human    85 CATFRQDGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLW 149

  Fly   151 DVANEKVVQTYEDTHTDYVRAGAMHPQAGHMFVSGGYDGKIKLYDTRAETAVQRTLDHGAPVESM 215
            |:.|.|.:.|::: |:||||.|........:|::|.||..:|::|.|...:| .:::||.||||:
Human   150 DIPNSKEILTFKE-HSDYVRCGCASKLNPDLFITGSYDHTVKMFDARTSESV-LSVEHGQPVESV 212

  Fly   216 LFLPNGSIFVSAGGSQVRVWDLISGCRLLTMMSQHHKTVTCLRLGSDGRRLLSGGLDRHVKIYDV 280
            |..|:|.:.|||||..|:|||::.|.:||..:..||||||||.|.|.|:|||||.|||.||:|..
Human   213 LLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYST 277

  Fly   281 STYKTVHTLTYPNAVVSMAVADGDQAVVAGMVDGLVSIRRMMVDSKPSHLKKIRADRARKYFVST 345
            ::||.||:..|..:::|:|:|..|:.:|.||.:|::|::....::|...|.:.|....|.:.
Human   278 TSYKVVHSFDYAASILSLALAHEDETIVVGMTNGILSVKHRKSEAKKESLPRRRRPAYRTFI--- 339

  Fly   346 KRTNNTQEVDHTIKDHVKGPGLKSYDVHLRQFNHKKALDDVMNAQKMQYQPELIVAVITDLLHRG 410
            |..|..::.|..:.:......|:.||..|:.|...||||.|::.......||:.|::|.:|..||
Human   340 KGKNYMKQRDDILINRPAKKHLELYDRDLKHFRISKALDRVLDPTCTIKTPEITVSIIKELNRRG 404

  Fly   411 SLGKALTGRHEAALVRFIDFICNHLGEVRFMRPLMMAASTVLDVFEQRLVAYSQKLMKALQRLSL 475
            .|..||.||.|..:...::|:..:|.:.||...|:.||..::|:: ..::..|..:.|....|..
Human   405 VLANALAGRDEKEISHVLNFLIRNLSQPRFAPVLINAAEIIIDIY-LPVIGQSPVVDKKFLLLQG 468

  Fly   476 AMQEEVRLTAELMRMKGAVDML 497
            .:::|:....||:...|.:|||
Human   469 LVEKEIDYQRELLETLGMMDML 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3071	NP_569993.1	WD40	4..316	CDD:441893	139/294 (47%)
		WD40 repeat	87..121	CDD:293791	22/33 (67%)
		WD40 repeat	126..162	CDD:293791	17/35 (49%)
		WD40 repeat	170..206	CDD:293791	10/35 (29%)
		WD40 repeat	212..247	CDD:293791	18/34 (53%)
		WD40 repeat	254..288	CDD:293791	21/33 (64%)
		WD40 repeat	295..318	CDD:293791	8/22 (36%)
		UTP15_C	349..497	CDD:462782	41/147 (28%)
UTP15	NP_115551.2	WD 1	36..75		14/38 (37%)
		WD40	39..307	CDD:441893	128/269 (48%)
		WD40 repeat	41..79	CDD:293791	14/37 (38%)
		WD 2	78..117		25/38 (66%)
		WD40 repeat	84..120	CDD:293791	23/35 (66%)
		WD 3	120..159		19/38 (50%)
		WD40 repeat	125..161	CDD:293791	17/35 (49%)
		WD 4	162..202		14/41 (34%)
		WD40 repeat	169..202	CDD:293791	9/33 (27%)
		WD 5	204..242		20/37 (54%)
		WD40 repeat	209..245	CDD:293791	18/35 (51%)
		WD 6	246..285		25/38 (66%)
		WD40 repeat	251..277	CDD:293791	18/25 (72%)
		WD 7	287..326		11/38 (29%)
		WD40 repeat	292..327	CDD:293791	10/34 (29%)
		UTP15_C	343..490	CDD:462782	41/147 (28%)