DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3071 and mip1

DIOPT Version :9

Sequence 1:	NP_569993.1	Gene:	CG3071 / 31213	FlyBaseID:	FBgn0023527	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_593370.1	Gene:	mip1 / 2542404	PomBaseID:	SPAC57A7.11	Length:	1313	Species:	Schizosaccharomyces pombe

Alignment Length:	396	Identity:	68/396 - (17%)
Similarity:	128/396 - (32%)	Gaps:	117/396 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 RAQVETPDTVY---WDR--LAKPELLKEHNTIDYLDFSPSDPDNFVVTCSVRVQIYNLVTMLVVK 75
            :::::.|.|.|   |.|  ..:|::            .|::.|.....|      ||.......:
pombe   914 QSELDMPLTSYLFDWSRKYFTEPQM------------RPNEDDEPGSIC------YNQRLWRRNR 960

  Fly    76 NLSRFQKTAYGATFRQDGRLLAAGDEEGHVKLFDTTSRNILRLFKGHTAPVHRTFFTADKLQLAS 140
            |.....:|...|.:..:||.                 ...|..|....|| .:..|...:.||.:
pombe   961 NEKLIYRTRPLAEYSTNGRW-----------------NQQLMTFNNTIAP-RKLMFHQFEDQLIT 1007

  Fly   141 FGDDKSVRLWDVANEKVVQTYE---DTHTDYVRAGAMHPQAGHMFVSGGYDGKIKLYDTRAETAV 202
            .||...:::||....:.:.:::   ...|:......::.....:.::|..||.||||.......|
pombe  1008 LGDKDIIQVWDWRRNRCLNSFKTSASATTNVTDMQLLNEDDVALLMTGSSDGTIKLYRDYENEKV 1072

  Fly   203 QRTLDHGAPVESMLFLPNGSIFVS----------AGGSQV-RVWDL------------------- 237
            :......:..:.:....|.|:.:|          ||..:| |:||.
pombe  1073 ELVTSWNSLSDLVFGDRNASLLMSWQQNCGHLLVAGDVRVIRIWDASKEICYANLPVRSSNSITS 1137

  Fly   238 ----ISGCRLLT-----------------------MMSQHHKTVTCLRLGSDG-RRLLSGGLDRH 274
                :.||.::.                       :..:|...:..:.:.|.| |.|:|...|..
pombe  1138 LTSDLVGCNIIVAGFSDGVLRVYDKRLPARDSLTDVWKEHSSEIVNVEMQSSGMRELISASSDGE 1202

  Fly   275 VKIYDVSTYKTVHTLTYPNA-VVSMAVADGDQAVVAGMVDGLVSI--------------RRMMVD 324
            ||::|:....::.|.:..|: :.|:.|.........|..:..:.|              .|.:..
pombe  1203 VKLWDIRMNHSLQTFSTDNSGLTSLTVHSHAPVYATGSSNQSIKIWDTLGQNINTFRENPRFLNQ 1267

  Fly   325 SKPSHL 330
            .|||.|
pombe  1268 PKPSSL 1273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3071	NP_569993.1	WD40	<26..283	CDD:225201	55/322 (17%)
		WD40 repeat	87..121	CDD:293791	5/33 (15%)
		WD40	89..318	CDD:238121	48/290 (17%)
		WD40 repeat	126..162	CDD:293791	7/35 (20%)
		WD40 repeat	170..206	CDD:293791	8/35 (23%)
		WD40 repeat	212..247	CDD:293791	11/91 (12%)
		WD40 repeat	254..288	CDD:293791	9/34 (26%)
		WD40 repeat	295..318	CDD:293791	3/22 (14%)
		UTP15_C	352..494	CDD:286472
mip1	NP_593370.1	Raptor_N	119..265	CDD:291222
		WD40	981..1249	CDD:295369	47/268 (18%)
		WD40	998..>1305	CDD:225201	48/276 (17%)
		WD40 repeat	1039..1080	CDD:293791	8/40 (20%)
		WD40 repeat	1085..1128	CDD:293791	9/42 (21%)
		WD40 repeat	1136..1174	CDD:293791	2/37 (5%)
		WD40 repeat	1181..1218	CDD:293791	10/36 (28%)
		WD40 repeat	1224..1266	CDD:293791	5/41 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910