DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3071 and SPCC63.06

DIOPT Version :9

Sequence 1:	NP_569993.1	Gene:	CG3071 / 31213	FlyBaseID:	FBgn0023527	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_587980.1	Gene:	SPCC63.06 / 2538796	PomBaseID:	SPCC63.06	Length:	331	Species:	Schizosaccharomyces pombe

Alignment Length:	324	Identity:	69/324 - (21%)
Similarity:	129/324 - (39%)	Gaps:	49/324 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 DNFVVTCSV-RVQIYNLVTMLVVKNLSRFQKTAYG-ATFRQDGRLLAAGDEEGHVKLFDTTS--R 113
            ||.||:.|. ....::..|:|.:..:.:......| .:..|...::..| .||.:.|:|..|  :
pombe    26 DNVVVSYSTGSWSCFDKGTLLEIFKVPKAHTNITGIISCDQLNGVITCG-SEGEIHLWDIRSQAK 89

  Fly   114 NILRLFKGHTAPVHRTFFTADKLQLASFGDD-----KSVRLWDVANE-KVVQTYEDTHTDYVRAG 172
            :.:|.:...:.|.  |....:|....:.|.:     .||:||||.:| |:::.:.|.|.|.:...
pombe    90 SAVRSWTQQSTPF--TCIALNKKNQFATGSELTRSLASVQLWDVRSEQKLIRQWNDAHNDDITHL 152

  Fly   173 AMHPQAGHMFVSGGYDGKIKLYDTRAETAVQRTLDHGAPVESMLFLPNGSIFVSAGGSQVRVWDL 237
            ..||:...:.::|..||.:.|.||..|.      |...|.|..|      :.|...|:.:.:...
pombe   153 QFHPKDNELLLTGSVDGLVSLLDTTKEE------DSTDPEEDPL------LHVINHGASIHLAKF 205

  Fly   238 ISGCRLLTMMSQHHKTVTCLRLGSDGRRLLSGGLDRHVKIYDVSTYKTVHTLTYPNAVVSMAVAD 302
            :|..|::.:.......:..|:...|.:...|.      :::.:...:...:.:|    |...|:.
pombe   206 VSKKRVMVLSHMESYAMYKLKRDKDEKTWSSN------ELFSIDDLRAELSCSY----VINEVST 260

  Fly   303 GDQAVVAGMVDGLVS---IRRMMVDSKPSHLKKIRADRARKYFVSTKRTNNTQEVDHTIKDHVK 363
            .|:...| :..|..|   .:.::||:....|||          ..||....::|:...|...||
pombe   261 SDKQFCA-LAFGDFSNHETKFVLVDTSTGELKK----------EPTKLERASEEICRAISFDVK 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3071	NP_569993.1	WD40	<26..283	CDD:225201	51/239 (21%)
		WD40 repeat	87..121	CDD:293791	8/35 (23%)
		WD40	89..318	CDD:238121	50/239 (21%)
		WD40 repeat	126..162	CDD:293791	11/41 (27%)
		WD40 repeat	170..206	CDD:293791	9/35 (26%)
		WD40 repeat	212..247	CDD:293791	6/34 (18%)
		WD40 repeat	254..288	CDD:293791	3/33 (9%)
		WD40 repeat	295..318	CDD:293791	6/25 (24%)
		UTP15_C	352..494	CDD:286472	4/12 (33%)
SPCC63.06	NP_587980.1	WD40	5..>331	CDD:225201	69/324 (21%)
		WD40	47..>180	CDD:295369	32/135 (24%)
		WD40 repeat	59..97	CDD:293791	9/38 (24%)
		WD40 repeat	102..142	CDD:293791	11/41 (27%)
		WD40 repeat	150..185	CDD:293791	10/40 (25%)
		WD40 repeat	200..241	CDD:293791	5/46 (11%)
		WD40 repeat	255..298	CDD:293791	12/53 (23%)
		Salt_tol_Pase	<261..330	CDD:302929	15/64 (23%)
		WD40 repeat	305..329	CDD:293791	3/9 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910