DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment temp and rabggta

DIOPT Version :9

Sequence 1:	NP_001284818.1	Gene:	temp / 31212	FlyBaseID:	FBgn0027296	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_001070131.1	Gene:	rabggta / 767725	ZFINID:	ZDB-GENE-060929-1042	Length:	580	Species:	Danio rerio

Alignment Length:	274	Identity:	67/274 - (24%)
Similarity:	112/274 - (40%)	Gaps:	73/274 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 QTTAQQLRTLQQQQQS---------DSLAKYLNVA-------------LLINPDVTTFWHIRRQL 119
            :|||||....:::::.         ||:.|..:..             |..|||..|.|:.||::
Zfish     8 KTTAQQEEEKRKEREKKLKAFVCARDSVLKKRSAGEHDEEALDLTQQLLSSNPDFATLWNYRREV 72

  Fly   120 V-------QKNRLS--INKELQFSALVLSIKPKSNEAFAYRRWLYSFQSADAIDWPNEIGICERA 175
            :       :|:.:.  ...||.|....|.:.|||...:.:|.|:.:  .....||..|:|:|
Zfish    73 LLHLETLREKDEVQKLYESELHFIEACLKVNPKSYGCWHHRSWVNT--RLPQPDWTRELGLC--- 132

  Fly   176 ADRCAS----NYHAWSHRQWILQNGPCLLQSELLRTEKFMRKHISDYSCYHYRQVLLSR------ 230
             |||.|    |:|.|.:|:.:::.....::.||..|::.:..:.|:||.:|||..||.:
Zfish   133 -DRCLSLDERNFHCWDYRRLVVKESGVSVEQELQFTDRLIGSNFSNYSSWHYRSTLLPQLRPQPV 196

  Fly   231 ---AYELSFALPKDSGASGSSTLASLQHLMTSYGLECEANAED------------LLGLLLPHVD 280
               |:..| ..|..|..|.|..:.. :.|:..|.|...|...|            |||
Zfish   197 LDSAHNTS-PSPSASPQSHSHRVCE-EQLLKEYELAHNAFFTDPNDQSAWFYYRWLLG------- 252

  Fly   281 LSSVSKQRLISFLY 294
              ...::.:||.:|
Zfish   253 --RAEREEMISCVY 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
temp	NP_001284818.1	PPTA	168..195	CDD:279565	11/30 (37%)
rabggta	NP_001070131.1	BET4	38..>252	CDD:227823	54/221 (24%)
		PPTA	92..116	CDD:279565	8/23 (35%)
		PPTA	128..154	CDD:279565	11/29 (38%)
		PPTA	163..190	CDD:279565	11/26 (42%)
		PPTA	226..253	CDD:279565	7/35 (20%)
		RabGGT_insert	260..359	CDD:285012	3/5 (60%)
		LRR_RI	325..580	CDD:238064
		leucine-rich repeat	456..474	CDD:275378
		leucine-rich repeat	475..500	CDD:275378
		LRR_8	478..533	CDD:290566
		leucine-rich repeat	501..522	CDD:275378
		leucine-rich repeat	523..547	CDD:275378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5536
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1527547at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820