DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment temp and Rabggta

DIOPT Version :9

Sequence 1:NP_001284818.1 Gene:temp / 31212 FlyBaseID:FBgn0027296 Length:398 Species:Drosophila melanogaster
Sequence 2:NP_113842.1 Gene:Rabggta / 58983 RGDID:621697 Length:567 Species:Rattus norvegicus


Alignment Length:357 Identity:82/357 - (22%)
Similarity:142/357 - (39%) Gaps:75/357 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 RRQTTAQQLRTLQQQQQS-----------DSLAKYLNVALLINPDVTTFWHIRRQLVQ------- 121
            :|....|:|:..|...|:           :|:.:..:..|..|||..|.|:.||:::|       
  Rat    17 KRLEREQKLKLYQSATQAVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVLQHLETEKS 81

  Fly   122 --KNRLSINKELQFSALVLSIKPKSNEAFAYRRWLYSFQSADAIDWPNEIGICERAADRCASNYH 184
              ::...:..||.|....|.:.|||...:.:|.||.|  .....:|..|:.:|.|..:....|:|
  Rat    82 PEESAALVKAELGFLESCLRVNPKSYGTWHHRCWLLS--RLPEPNWARELELCARFLEADERNFH 144

  Fly   185 AWSHRQWILQNGPCLLQSELLRTEKFMRKHISDYSCYHYRQVLLSRAYELSFALPK-DSGASG-- 246
            .|.:|:::..........||..|:..:.::.|:||.:|||..||.:.:      |: |||..|  
  Rat   145 CWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLH------PQPDSGPQGRL 203

  Fly   247 --SSTLASLQHLMTSYGLECEANAED-------LLGLLLPHVDLSSVSKQRLISFLYCCNVAAND 302
              :..|..|:.:..::  ..:.|.:.       |||...||            ..|.|.:|:..:
  Rat   204 PENVLLKELELVQNAF--FTDPNDQSAWFYHRWLLGRAEPH------------DVLCCVHVSREE 254

  Fly   303 --MRLCAEQRLMYGSRDCFELHRRAALKFIVEQC-VRLQMGLPNGQL---------LPVASGDLR 355
              :.:|..:.|..||       |...|..:|::. :.::...|:|:.         ||.||  |.
  Rat   255 ACLSVCFSRPLTVGS-------RMGTLLLMVDEAPLSVEWRTPDGRNRPSHVWLCDLPAAS--LN 310

  Fly   356 SHLGNFDFEDNPFLSAVRREESTLGGKHRRWC 387
            ..|....|......|..::|...|..:...||
  Rat   311 DQLPQHTFRVIWTGSDSQKECVLLKDRPECWC 342

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tempNP_001284818.1 PPTA 168..195 CDD:279565 7/26 (27%)
RabggtaNP_113842.1 BET4 1..>237 CDD:227823 54/229 (24%)
PFTA 1 44..78 10/33 (30%)
PFTA 2 88..122 11/35 (31%)
PPTA 92..119 CDD:279565 11/28 (39%)
PFTA 3 124..158 8/33 (24%)
PPTA 128..151 CDD:279565 7/22 (32%)
PFTA 4 159..193 11/39 (28%)
PPTA 163..190 CDD:279565 11/26 (42%)
PFTA 5 207..241 6/35 (17%)
PPTA 211..238 CDD:279565 4/28 (14%)
RabGGT_insert 247..346 CDD:285012 23/105 (22%)
LRR_RI <351..548 CDD:238064
PFTA 6 363..397
LRR 1 442..463
LRR_8 443..498 CDD:290566
leucine-rich repeat 443..461 CDD:275378
leucine-rich repeat 462..487 CDD:275378
LRR 2 464..486
LRR 3 487..508
LRR_8 488..545 CDD:290566
leucine-rich repeat 488..509 CDD:275378
LRR 4 509..530
leucine-rich repeat 510..534 CDD:275378
LRR 5 534..555
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5536
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1527547at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.820

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