DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment temp and Rabggta

DIOPT Version :9

Sequence 1:	NP_001284818.1	Gene:	temp / 31212	FlyBaseID:	FBgn0027296	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_001347316.1	Gene:	Rabggta / 56187	MGIID:	1860443	Length:	567	Species:	Mus musculus

Alignment Length:	357	Identity:	83/357 - (23%)
Similarity:	142/357 - (39%)	Gaps:	75/357 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 RRQTTAQQLRTLQQQQQS-----------DSLAKYLNVALLINPDVTTFWHIRRQLVQKNRLS-- 126
            :|....|:|:..|...|:           :|:.:..:..|..|||..|.|:.||:::|:....
Mouse    17 KRLEREQKLKLYQSATQAVFQKREAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQKS 81

  Fly   127 -------INKELQFSALVLSIKPKSNEAFAYRRWLYSFQSADAIDWPNEIGICERAADRCASNYH 184
                   :..||.|....|.:.|||...:.:|.||.|  .....:|..|:.:|.|..:....|:|
Mouse    82 PEELAALVKAELGFLESCLRVNPKSYGTWHHRCWLLS--RLPEPNWARELELCARFLEADERNFH 144

  Fly   185 AWSHRQWILQNGPCLLQSELLRTEKFMRKHISDYSCYHYRQVLLSRAYELSFALPK-DSGASG-- 246
            .|.:|:::..........||..|:..:.::.|:||.:|||..||.:.:      |: |||..|
Mouse   145 CWDYRRFVAAQAAVAPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLH------PQPDSGPQGRL 203

  Fly   247 --SSTLASLQHLMTSYGLECEANAED-------LLGLLLPHVDLSSVSKQRLISFLYCCNVAAND 302
              :..|..|:.:..::  ..:.|.:.       |||...||            ..|.|.:|:..:
Mouse   204 PENVLLRELELVQNAF--FTDPNDQSAWFYHRWLLGRAEPH------------DVLCCLHVSREE 254

  Fly   303 --MRLCAEQRLMYGSRDCFELHRRAALKFIVEQC-VRLQMGLPNGQL---------LPVASGDLR 355
              :.:|..:.|:.||       :...|...|::. :.::...|:|:.         ||.||  |.
Mouse   255 ACLSVCFSRPLIVGS-------KMGTLLLTVDEAPLSVEWRTPDGRNRPSHVWLCDLPAAS--LN 310

  Fly   356 SHLGNFDFEDNPFLSAVRREESTLGGKHRRWC 387
            .||....|......|..::|...|.|....||
Mouse   311 DHLPQHTFRVIWTGSDTQKECVLLKGHQECWC 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
temp	NP_001284818.1	PPTA	168..195	CDD:279565	7/26 (27%)
Rabggta	NP_001347316.1	PPTA	1..>237	CDD:332411	54/229 (24%)
		PFTA 1	44..78		10/33 (30%)
		PFTA 2	88..122		11/35 (31%)
		PFTA 3	124..158		8/33 (24%)
		PFTA 4	159..193		11/39 (28%)
		PFTA 5	207..241		6/35 (17%)
		RabGGT_insert	247..346	CDD:311580	24/105 (23%)
		LRR	<354..>520	CDD:227223
		PFTA 6	363..397
		LRR 1	442..463
		leucine-rich repeat	443..461	CDD:275378
		leucine-rich repeat	462..487	CDD:275378
		LRR 2	464..486
		LRR_9	<468..562	CDD:317038
		LRR 3	487..508
		leucine-rich repeat	488..509	CDD:275378
		LRR 4	509..530
		leucine-rich repeat	510..534	CDD:275378
		LRR 5	534..555
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5536
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1527547at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820