DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment temp and M57.2

DIOPT Version :9

Sequence 1:	NP_001284818.1	Gene:	temp / 31212	FlyBaseID:	FBgn0027296	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_500367.1	Gene:	M57.2 / 177113	WormBaseID:	WBGene00019778	Length:	580	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	54/208 - (25%)
Similarity:	91/208 - (43%)	Gaps:	37/208 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 QQQQQSDSLAKYLNVALLINPDVTTFWHIRRQLVQKNRLSINKELQFSA---------------- 135
            ::.:..|.:.......|..|.|:.|||:|||..::. |:..|:::|.||
Worm    40 EKGEYDDEILSLTQAILEKNADIYTFWNIRRTTIEL-RMEANEKVQQSADAEEEEKTKSSQKIEN 103

  Fly   136 -----LVLSIK-----PKSNEAFAYRRWLYSFQSADAIDWPNEIGICERAADRCASNYHAWSHRQ 190
                 |.||.:     |||..|:..|.|....|||.  |:..|:.:||:|......|:|.|.||:
Worm   104 LLAGELFLSYECIKSNPKSYSAWYQRAWALQRQSAP--DFKKELALCEKALQLDCRNFHCWDHRR 166

  Fly   191 WILQNGPCLLQSELLRTEKFMRKHISDYSCYHYRQVLLSRAYELSFALPKDSGAS--GSSTLAS- 252
            .:.:........||..:.|.:..:.|:||.:|||.:.|...:.     .:.:||.  ....:||
Worm   167 IVARMAKRSEAEELEFSNKLINDNFSNYSAWHYRSIALKNIHR-----DEKTGAPKIDDELIASE 226

  Fly   253 LQHLMTSYGLECE 265
            ||.:..::.::.|
Worm   227 LQKVKNAFFMDAE 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
temp	NP_001284818.1	PPTA	168..195	CDD:279565	9/26 (35%)
M57.2	NP_500367.1	BET4	37..>264	CDD:227823	54/208 (26%)
		PPTA	108..135	CDD:279565	9/26 (35%)
		TPR repeat	123..153	CDD:276809	11/31 (35%)
		PPTA	144..168	CDD:279565	9/23 (39%)
		TPR repeat	158..189	CDD:276809	8/30 (27%)
		PPTA	179..206	CDD:279565	10/26 (38%)
		PPTA	226..252	CDD:279565	3/14 (21%)
		LRR	405..>550	CDD:227223
		LRR_4	499..539	CDD:289563
		leucine-rich repeat	501..522	CDD:275378
		leucine-rich repeat	523..548	CDD:275378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1527547at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920