Protein Alignment Stard8 and cv-c

DIOPT Version :9

• Sequence 1: XP_038955618.1
• Gene: Stard8 / 312113
• RGDID: 1560770
• Length: 1136
• Species: Rattus norvegicus
• Sequence 2: NP_001097786.1
• Gene: cv-c / 41749
• FlyBaseID: FBgn0285955
• Length: 2351
• Species: Drosophila melanogaster
• Alignment Length: 1216
• Identity: 377/1216 - (31%)
• Similarity: 570/1216 - (46%)
• Gaps: 261/1216 - (21%)

  Rat     7 FSNLDSCSSTSTHAHSKGCGPC-----LC---RHYPCCLGFLSPSPSWNERE------TFLSWGL 57
            |..|.|.||.|.|:   |.|..     ||   ...|..|         .|||      .|.:..|
  Fly  1311 FVELPSPSSASLHS---GLGDSGGIQELCTKSNSAPMLL---------KEREMSRRFDNFEAQHL 1363

  Rat    58 EV---GSPRHKWCLEAEAKKACEWLRATGFPQYAQLFEEGVFPLDIGSVKKDYSFLDQDSLGALC 119
            .:   .|...::..|.||.:||:||||.|||||||::|:..||:|:.:|.||::.|:.|.|.:|.
  Fly  1364 TLRYSRSQSDRYLAEIEAVEACKWLRAAGFPQYAQMYEDHQFPIDLNNVAKDHTNLENDQLQSLY 1428

  Rat   120 RRLMTLNNCASMKLEVHFR--CKQDDDSEEEEQCTISSHWAFEQESKCGSLTGSSALLAPPSPSL 182
            |||..||.||:|:|:...:  ..|..:..::|...:|.||.|:...:..|..|...|..||
  Fly  1429 RRLCVLNRCATMRLDQSHKPQTPQQKEESDDENFALSEHWTFQPHIRRWSRIGEMGLELPP---- 1489

  Rat   183 PGTSSCESVLTELSAASLPAISVSLSP-----ESADLPLL-------GHVPSPSNQPFLSPTQGQ 235
            ||..|.....||.|       |...||     :.|.:.|:       |.:|:..:    |..:|.
  Fly  1490 PGLLSLNVEKTESS-------SKESSPDRFEEDGAGITLVTPGCSKAGGIPNDGS----SLGEGS 1543

  Rat   236 EGSQ------DKVKKHYSRSFLKHLESLR-RKEKGDSRQTEPEQRLATSEKATKASSFRTCRGLL 293
            :..:      :::|.. :::.|:.:||:: |:.|..:|:
  Fly  1544 DSGRLRRSGSERIKDQ-AKALLRRVESIKSRRRKRQNRE-------------------------- 1581

  Rat   294 SVGFHRAKNRVTTSPRVRDGETQKTWEAWPVATFRHPQPNRRHDCLVHVPRDHKPG------TFP 352
                    |.|.:.|.|.|           ::.|......|:.|.:...|  ..|.      |||
  Fly  1582 --------NVVISGPTVLD-----------LSQFGQRSSLRKPDAVYSTP--PSPSALSPMHTFP 1625

  Rat   353 RS--LSIESLCPDDSRHLADWQPNRCWGYEGRRGSCGSTGSHASTYDNLPELYPAEPIQAEAEDE 415
            ::  ...:...|..|.:..  .||        |.|...|.:...:....|..:.:.|:....|.:
  Fly  1626 KAPFFGNDLKVPSHSDNFL--SPN--------RSSPKRTPTTPRSMRTSPLHFFSSPMSQLKEGK 1680

  Rat   416 DEEGEGSYAHLDDILEHVWG--LQQRVELWSQAMYPDLRPGDKEEEEEEEEEATSSVEIATAEVE 478
            .::....|:   |..|...|  |..|                |..:.....:.|..|
  Fly  1681 SDDSSSYYS---DSQESSTGGKLSLR----------------KPSKARRFLQRTGKV-------- 1718

  Rat   479 GQDEALAQAESQVHRGFPTEVKEEVPLIVLDQAPTVVEPLVQAEAPAQAQHPEQDANSAAEPISA 543
              |:..|.::|:.|:|....:|                                ||||....:..
  Fly  1719 --DDIGAHSDSECHQGRKLLIK--------------------------------DANSNTTEVKV 1749

  Rat   544 SSLSVEEGHSIS-------DTAVSSSELDSSGNSVNEADVADALAGPNASVPRERRDSGVGASLT 601
            ..|:  .|.|::       .....||...|...|..||...:..||...:          |.|..
  Fly  1750 KKLT--RGGSLNLGKDPKKRDGFRSSSFRSRSTSRKEAKNDEDTAGATTN----------GGSKR 1802

  Rat   602 RPCRKLRWHSFQNSHRPSL---------------NSESLEINRQFAGQINLLHKGSLLRLTGFME 651
            :|.  :||||||...||::               ::..:......|||:.::.|.:|:.|||.||
  Fly  1803 QPV--VRWHSFQMEERPNMIFRKCFSKKIEPLQEDAGGMPFAAMSAGQLQIIRKLALVTLTGHME 1865

  Rat   652 KYTVPHKQAWVWSMPKFMKRNKTPDYRGHHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQ 716
            :|...|:..|.|.:|||:|:.|.|||:...|||||.|:.:||:||.||.:::.|.|:|:...|||
  Fly  1866 RYCPSHRSGWNWELPKFIKKIKMPDYKDKKVFGVPLLMILQRSGQTLPLAVRAAFRWLQLNALDQ 1930

  Rat   717 VGIFRKSGVKSRIQSLRQMNETSPDNV-C---YEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTF 777
            ||||||||.||||..||:..|.:.... |   ::.|.||||||:||||||:|||.:.|:|::.||
  Fly  1931 VGIFRKSGGKSRIMKLREQIEVTDSTAECMDVFDLQQAYDVADMLKQYFRELPESLLTTKMSETF 1995

  Rat   778 LQIYQLLPKEQWLAAAQAATLLLPDENREVLQTLLYFLSDI-ASAEENQMTAGNLAVCLAPSIFH 841
            :.|:|.||.|..|.|.|.|.|||||||||:|..||.||:.: |::::||||:.||.||||.||||
  Fly  1996 VAIFQHLPAEVRLDAVQCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLGVCLAQSIFH 2060

  Rat   842 LNVSKKD---SPSPRIKSKRSLVGRPGPRDLSENMAATQGLSHMISDCKKLFQVPQDMVVQLCGS 903
            .::|...   |.|||.|.|.|  |.|..::|:|..|:.:.||.||...|:::...::.:.: | :
  Fly  2061 SSISTGSASVSASPRRKGKGS--GMPDMKELAEAKASHECLSFMIEHYKQIYTAAKEKLSK-C-N 2121

  Rat   904 YSAAELTPPGPALAELRQAQAAGVSLSL-----YMEESVQELLRDAAERFKGW--TNVPGPQHTE 961
            :|..|.:.|.|       .:|.|..:..     |:.|.....:::..|:.:||  .|.......:
  Fly  2122 FSYMEESKPLP-------LEALGEGMQFHNWRGYLYECTSATIKEGREKTRGWFSINSLNDSSVD 2179

  Rat   962 LACRKAPDGHPLRMWKASTEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDS 1026
            :|.:|..||||||:|:.|||:..||..||..|:::||.||.:||:.|.::.|....|:|.|..|.
  Fly  2180 IAYKKVGDGHPLRLWRCSTEIEGPPKEVLEFVIKQRASWDTNLLQCQTVKKLDDRTEIYQYALDG 2244

  Rat  1027 MAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPESG-VRALMLTSQYLMEPCGLGRSRLT 1090
            ..   ..||.|||.|::|||||.|::|..|:|..:..|..| ||.::|.|:||:||||.||||:.
  Fly  2245 QL---TTDFCVLRSWQTDLPRGACVIVETSIDHAKAKPLFGAVRGVVLASRYLIEPCGSGRSRVM 2306

  Rat  1091 HICRADLRGRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETKL 1136
            |:.|.|::|::|:||||.:||:|:..:::||.:|..: |.|||:|:
  Fly  2307 HLARVDVKGKTPEWYNKNYGHICSHYLSRIRLAFKHV-ADGPESKV 2351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stard8	XP_038955618.1	SAM_DLC1,2-like	73..132	CDD:188937	31/58 (53%)
		RhoGAP	682..896	CDD:413382	110/221 (50%)
		SRPBCC	923..1127	CDD:417480	83/211 (39%)
cv-c	NP_001097786.1	SAM_DLC1,2-like	1382..1441	CDD:188937	31/58 (53%)
		RhoGAP_DLC1	1893..2116	CDD:239840	110/224 (49%)
		SRPBCC	2148..2343	CDD:301327	81/197 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	196	1.000	Domainoid score	I3033
eggNOG	1	0.900	-	-		E1_KOG2200
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001209
OrthoInspector	1	1.000	-	-		otm44733
orthoMCL	1	0.900	-	-		OOG6_103453
Panther	1	1.100	-	-	O	PTHR12659
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X752
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.810