DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3078 and Unc93a

DIOPT Version :9

Sequence 1:	NP_001356930.1	Gene:	CG3078 / 31211	FlyBaseID:	FBgn0023524	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	XP_038955786.1	Gene:	Unc93a / 685007	RGDID:	1583290	Length:	454	Species:	Rattus norvegicus

Alignment Length:	482	Identity:	110/482 - (22%)
Similarity:	202/482 - (41%)	Gaps:	122/482 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 GSLLLSALFLVAAGMSLPSIRLMKRYGYGPLIVANYMTVLLFLLSHLYASIYTLLPAYLLLGMTL 357
            ||:|||::|       ||.| |:|:.|....||.:....::|.|.:.:|:.|||:|..:|||:..
  Rat    48 GSVLLSSMF-------LPPI-LIKKCGCKWTIVGSMCCYVVFSLGNFHANWYTLIPTSILLGLGA 104

  Fly   358 SGSAGSKAALIVHFG-------GKLSCSCDSQQSQAAVDVLHEEHKMFCNRDQKVRRLARWFRVS 415
            :....::...:...|       |||           ..||:::...:|             |.:.
  Rat   105 APLWSAQCTYLTVIGNLQAEKVGKL-----------GKDVVNQYFGIF-------------FLIF 145

  Fly   416 QDLGLIGGALLASILLACSDGNFTGDCSGLVYYGNESWPPQLRDFYNRNEHGDRI--CGADMCPL 478
            |..| :.|.|::|::                 :|..|....:.|        :::  |||..|
  Rat   146 QSSG-VWGNLISSLV-----------------FGKMSMQDAIPD--------EQLMSCGAKDC-- 182

  Fly   479 RVQSILEAGWANGSSIPSS--IYAGFIESEPRVAGQSLLWLYVLFSMVSLTLSLLI---VVDKVQ 538
                ::.....|.:..||.  ||             :||.:|....::::.|..:.   |.||::
  Rat   183 ----LMGPSATNTTHHPSQQLIY-------------TLLGIYTSSGVLAILLVAVFLEPVKDKLE 230

  Fly   539 AIGSSRPERSRDVSITDTLLFAGP-------LAYFVGTEQAYMMGDFLRAFVTCSLGIGMIAGAL 596
            ..|.:|........::..:||...       |..:.|.:|.::.|::.:::|||:|||..:...:
  Rat   231 NEGETRSRPLWSTLLSTFMLFRDKRLCLLMFLPVYSGFQQGFLSGEYTKSYVTCALGIRFVGYVM 295

  Fly   597 IGMGLMQLIVSCTLSMLLRHVKRIVVILAGFFFH-SCLLLALSSWKPSSDDSALFYVIAASWGAC 660
            |....|..:.|.....:.::..||.:.:.|...| ||:::.| .|.|:.....:|:|::..||..
  Rat   296 ICFSAMTALCSLLYGKISKYTGRITLYVLGAAIHFSCIVVFL-LWHPNPAQLPVFFVLSGLWGMA 359

  Fly   661 NGMWET---LLLSLVTLNHSSHVTEVQAPLLALRFLG--LG--LTFAGHGFLCESMKIIALVVLL 718
            :.:|:|   :|..::       ..|.:.|..|...||  :|  :.|....|||.|.|:..|:.:|
  Rat   360 DAVWQTQNNVLFGVL-------FEENKEPAFANYRLGEAVGFVIAFGYSSFLCVSTKLYILLGVL 417

  Fly   719 VISVPPYATLEIR--------LEAQRK 737
            .:::..|.|:|.|        |.|:.|
  Rat   418 SVAMVSYGTVEYREYKAASKVLAAEEK 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3078	NP_001356930.1	bZIP	<11..>43	CDD:354818
CG3078	NP_001356930.1	MFS	<496..731	CDD:355786	60/254 (24%)
Unc93a	XP_038955786.1	MFS_unc93A_like	8..432	CDD:340964	107/468 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1145833at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19444
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020