DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3078 and Unc93a2

DIOPT Version :9

Sequence 1:	NP_001356930.1	Gene:	CG3078 / 31211	FlyBaseID:	FBgn0023524	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	NP_001136011.1	Gene:	Unc93a2 / 667055	MGIID:	3712668	Length:	458	Species:	Mus musculus

Alignment Length:	473	Identity:	108/473 - (22%)
Similarity:	195/473 - (41%)	Gaps:	111/473 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 SLLLSALFLVAAGMSLPSIRLMKRYGYGPLIVANYMTVLLFLLSHLYASIYTLLPAYLLLGMTLS 358
            |:|||::|       ||.| |:|:.|....||.:....::|.|.:.:|:.|||:|..:|||:..:
Mouse    49 SVLLSSMF-------LPPI-LIKKCGCKWTIVGSMCCYVVFSLGNFHANWYTLIPTSILLGLGAA 105

  Fly   359 GSAGSKAALIVHFG-------GKLSCSCDSQQSQAAVDVLHEEHKMFCNRDQKVRRLARWFRVSQ 416
            ....::...:...|       |||           ..||:::...:|             |.|.|
Mouse   106 PLWSAQGTYLTTMGNLQAEKVGKL-----------GKDVVNQYFGIF-------------FLVFQ 146

  Fly   417 DLGLIGGALLASILLACSDGNFTGDCSGLVYYGNESWPPQLRDFYNRNEHGDRICGADMCPLRVQ 481
            ..| :.|.|::|::                 :|..|....:      .|.....|||..|
Mouse   147 SSG-VWGNLISSLV-----------------FGKMSMQEAI------PEEQLMSCGAKDC----- 182

  Fly   482 SILEAGWANGSSIPSS--IYAGFIESEPRVAGQSLLWLYVLFSMVSLTLSLLIVV------DKVQ 538
             ::.....|.:..||.  ||             :||.:|....::::   ||:.|      ||::
Mouse   183 -LMGPAATNSTHHPSQQLIY-------------TLLGIYTGCGVLAI---LLVAVFLESLEDKLE 230

  Fly   539 AIGSSRPERSRDVSITDTL-----LFAGP-------LAYFVGTEQAYMMGDFLRAFVTCSLGIGM 591
            ..|..||   |...:..||     ||...       |..:.|.:|.::.|::.:::|||:|||..
Mouse   231 NEGERRP---RPPPLWSTLLSTFMLFRDKRLCLLMFLPLYSGFQQEFLSGEYTKSYVTCALGIHF 292

  Fly   592 IAGALIGMGLMQLIVSCTLSMLLRHVKRIVVILAGFFFH-SCLLLALSSWKPSSDDSALFYVIAA 655
            :...:|....|..:.|.....:.::..|..:...|...| ||:::.| .|.|:::...:|:|::.
Mouse   293 VGYVMICFSAMTALCSLLYGKISKYTGRAALYALGAAIHFSCVVVFL-LWHPNTNQLPVFFVLSG 356

  Fly   656 SWGACNGMWETLLLSLVTLNHSSHVTEVQAPLLALRFLGLGLTFAGHGFLCESMKIIALVVLLVI 720
            .||..:.:|:|...:|..:....:.....|.......:|..:.|....|||.|.|:..|:.:|.:
Mouse   357 LWGMSDAVWQTQNNALFGVLFEENKEPAFANYRLGEAIGFVIAFGYSSFLCVSTKLYILLGVLSL 421

  Fly   721 SVPPYATLE-IRLEAQRK 737
            ::..|.|:| :.::|..|
Mouse   422 AMVGYGTVEYLEVKAASK 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3078	NP_001356930.1	bZIP	<11..>43	CDD:354818
CG3078	NP_001356930.1	MFS	<496..731	CDD:355786	60/256 (23%)
Unc93a2	NP_001136011.1	MFS_unc93A_like	8..433	CDD:340964	106/465 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3097
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1145833at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19444
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920