DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3078 and Unc93b1

DIOPT Version :9

Sequence 1:	NP_001356930.1	Gene:	CG3078 / 31211	FlyBaseID:	FBgn0023524	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	NP_062322.2	Gene:	Unc93b1 / 54445	MGIID:	1859307	Length:	619	Species:	Mus musculus

Alignment Length:	527	Identity:	111/527 - (21%)
Similarity:	204/527 - (38%)	Gaps:	126/527 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 LSLAHGLMNCVLLPVMALQGSNAVWHHREEWLPLG------PEVGSLLLSALFLVAAGMSLPSIR 313
            ::|.:|    |.|.::.:|   .:.|:.|.:..:.      |::.|.:|       .|:::..|.
Mouse    92 VTLTYG----VYLGLLQMQ---LILHYDETYREVKYGNMGLPDIDSKML-------MGINVTPIA 142

  Fly   314 LMKRYGYGPLIVANYMTV-LLFLLSHLYA---------SIYTLLPAYLLLGMTLSGSAGSKAALI 368
            .:.   |.|:::..:.|. ::||...:||         ..|||:|:.:.|||.:       ..|.
Mouse   143 ALL---YTPVLIRFFGTKWMMFLAVGIYALFVSTNYWERYYTLVPSAVALGMAI-------VPLW 197

  Fly   369 VHFGGKLSCSCDSQQSQAAVDVLHEEHKMFCNRDQKVRR--LARWFRVSQDLGLIGGALLAS--- 428
            ...|..:     ::.||...:..|.:.:......|:..|  .|.:..|.|       |:..|
Mouse   198 ASMGNYI-----TRMSQKYYEYSHYKEQDEQGPQQRPPRGSHAPYLLVFQ-------AIFYSFFH 250

  Fly   429 ILLACSDGNFTGDCSGLVYYGNESWPPQLRDFYNRNEHGDRICGADMCPLRVQSILEAGWANGSS 493
            :..||:.       ..::|:.|..       .|:.|.   .:.....|..:.|.||     ||.:
Mouse   251 LSFACAQ-------LPMIYFLNNY-------LYDLNH---TLINVQSCGTKSQGIL-----NGFN 293

  Fly   494 IPSSIYAGFIESEPRVAGQSLLWLYVLFSMVSLTLSLLIVVDKVQAIGSSRPERSRDV-SITDTL 557
              .::......|:..:..:|:|       |....|::|:|:....|  :.||....|: |:....
Mouse   294 --KTVLRTLPRSKNLIVVESVL-------MAVAFLAMLMVLGLCGA--AYRPTEEIDLRSVGWGN 347

  Fly   558 LFAGP------------LAYFV--GTEQAYMMGDFLRAFVTCSLGIGMIAGALIGMGLMQLIVSC 608
            :|..|            :.:|:  |.|..:....|...:..||:|:..:|..||...| ....|.
Mouse   348 IFQLPFKHVRDFRLRHLVPFFIYSGFEVLFACTGFALGYGVCSMGLERLAYLLIAYSL-GASASS 411

  Fly   609 TLSMLLRHVKRIVVILAGFFFHSCLLLALSSWKPSS---DDSALFYVIAASWGACNGMWETLLLS 670
            .|.:|...:.|.|.::||...|..|.|:|..|.|:.   ..|.:||.:||.||..:.:.:|.|.:
Mouse   412 VLGLLGLWLPRSVPLVAGAGLHLLLTLSLFFWAPAPRVLQHSWIFYFVAALWGVGSALNKTGLST 476

  Fly   671 LVTLNHSSHVTE---------VQAPLLALRFLGLGLTFAGHGFLCESMKIIALVVLLVISVPPYA 726
            |:.:.:.....:         .||..:.:.:||..|..        ..|:..|:|.||.:...|.
Mouse   477 LLGILYEDKERQDFIFTIYHWWQAVAIFVVYLGSSLPM--------KAKLAVLLVTLVAAAASYL 533

  Fly   727 TLEIRLE 733
            .:|.:|:
Mouse   534 WMEQKLQ 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3078	NP_001356930.1	bZIP	<11..>43	CDD:354818
CG3078	NP_001356930.1	MFS	<496..731	CDD:355786	60/261 (23%)
Unc93b1	NP_062322.2	MFS	<145..>210	CDD:304372	17/79 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835069
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3097
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700