DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3078 and Unc93b1

DIOPT Version :9

Sequence 1:	NP_001356930.1	Gene:	CG3078 / 31211	FlyBaseID:	FBgn0023524	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	NP_001101983.1	Gene:	Unc93b1 / 361689	RGDID:	1311984	Length:	630	Species:	Rattus norvegicus

Alignment Length:	527	Identity:	111/527 - (21%)
Similarity:	201/527 - (38%)	Gaps:	117/527 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 SLAHGLMNCVLLPVMALQGSNAVWHHREEWLPLG------PEVGSLLLSALFL--VAAGMSLP-- 310
            :|.:|    |.|.::.:|   .:.|:.|.:..:.      |::.|.:|..:.:  :||.:..|
  Rat    93 TLTYG----VYLGLLQMQ---LILHYDETYREVKYGNMGLPDIDSKMLMGINVTPIAALLYTPVL 150

  Fly   311 -------SIRLMKRYGYGPLIVANYMTVLLFLLSHLYASIYTLLPAYLLLGMTLSGSAGSKAALI 368
                   |:.|.:.:|...::........||:.::.:...|||:|:.:.|||.:       ..|.
  Rat   151 IRPKVLMSLPLYRFFGTKWMMFLAVGIYALFVSTNYWERYYTLVPSAVALGMAI-------VPLW 208

  Fly   369 VHFGGKLSCSCDSQQSQAAVDVLHEEHKMFCNRDQKVRR--LARWFRVSQDLGLIGGALLAS--- 428
            ...|..:     ::.||...:..|.:.:......|:..|  .|.:..|.|       |:..|
  Rat   209 ASMGNYI-----TRMSQKYYEYSHYKEQDEQGPQQRPPRGSHAPYLLVFQ-------AIFYSFFH 261

  Fly   429 ILLACSDGNFTGDCSGLVYYGNESWPPQLRDFYNRNEHGDRICGADMCPLRVQSILEAGWANGSS 493
            :..||:.       ..:||:.|.    .|.|. |......:.||..          ..|..||.:
  Rat   262 LSFACAQ-------LPMVYFLNH----YLYDL-NHTLFNVKSCGTK----------SYGILNGFN 304

  Fly   494 IPSSIYAGFIESEPRVAGQSLLWLYVLFSMVSLTLSLLIVVDKVQAIGSSRPERSRDV-SITDTL 557
              .::......|...:..:|:|       |....|::|:|:....|  :.||....|: |:....
  Rat   305 --KTVLRTLPRSRNLIVVESVL-------MAVAFLAMLLVLGLCGA--AYRPTEEIDLRSVGWGN 358

  Fly   558 LFAGP------------LAYFV--GTEQAYMMGDFLRAFVTCSLGIGMIAGALIGMGLMQLIVSC 608
            :|..|            :.:|:  |.|..:....|...:..||:|:..:|..||...|.....|
  Rat   359 IFQLPFKHVRDFRLRHLVPFFIYSGFEVLFACTGFTLGYGVCSMGLERLAYLLIAYSLGASAAS- 422

  Fly   609 TLSMLLRHVKRIVVILAGFFFHSCLLLALSSWKPSS---DDSALFYVIAASWGACNGMWETLLLS 670
            .|.:|...:.|.|.::||...|..|.|:|..|.|:.   ..|.:||.:||.||..:.:.:|.|.:
  Rat   423 VLGLLGLWLPRSVPLVAGAGLHLLLTLSLFFWAPAPRVLQHSWIFYFVAALWGVGSALNKTGLST 487

  Fly   671 LVTLNHSSHVTE---------VQAPLLALRFLGLGLTFAGHGFLCESMKIIALVVLLVISVPPYA 726
            |:.:.:.....:         .||..:.:.:||..|..        ..|:..|:|.||.:...|.
  Rat   488 LLGILYEDKERQDFIFTIYHWWQAVAIFVVYLGSSLPM--------KAKLAVLLVTLVAAATSYL 544

  Fly   727 TLEIRLE 733
            .:|.:|:
  Rat   545 WMENKLQ 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3078	NP_001356930.1	bZIP	<11..>43	CDD:354818
CG3078	NP_001356930.1	MFS	<496..731	CDD:355786	60/261 (23%)
Unc93b1	NP_001101983.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338667
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3097
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700