DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3091 and SEC14L5

DIOPT Version :9

Sequence 1:	NP_001284816.1	Gene:	CG3091 / 31210	FlyBaseID:	FBgn0029608	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_055507.1	Gene:	SEC14L5 / 9717	HGNCID:	29032	Length:	696	Species:	Homo sapiens

Alignment Length:	331	Identity:	63/331 - (19%)
Similarity:	116/331 - (35%)	Gaps:	72/331 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDKDTGDKDSAPETSASPATGWSDKLTDLVAWF-EANPNLPEKIEPIVMLRFLKCTAFDVERTKA 64
            ||.|..|.|................|..|..|. |.:.....|.|.|  ||||:...|.:::.:.
Human   221 MDGDKLDADYIERCLGHLTPMQESCLIQLRHWLQETHKGKIPKDEHI--LRFLRAHDFHLDKARE 283

  Fly    65 LAELNYCMRN-----------KSPHLFMDRNMEDEMTAEGLRVSDLLILPGVTPQGNKLIFFRMA 118
            :...:...|.           :.|.|.      :|..|.|....|:        .|..|...|:.
Human   284 MLRQSLSWRKQHQVDLLLQTWQPPALL------EEFYAGGWHYQDI--------DGRPLYILRLG 334

  Fly   119 DLDPR--TRNSVEETKIFVMMSDARFTKPDVERETGSGADYVLDEADIAEGDVQ----------- 170
            .:|.:  .:...||..:..::|         ..|.|...         .||..:
Human   335 QMDTKGLMKAVGEEALLRHVLS---------VNEEGQKR---------CEGSTRQLGRPISSWTC 381

  Fly   171 IVDIGGYTLRHLAYVSIFVLRVYMKFLQEAYPSRLQAMHVINCPTYLDKLISMMSPFLREEVRNM 235
            ::|:.|..:|||....:..|...::.:::.||..|..:.::..|.....|.:::|||:.|..|..
Human   382 LLDLEGLNMRHLWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLISPFINENTRRK 446

  Fly   236 IRYHT----EGMDSLYKEVPRDMLPNEYGGKAGTVAELKAKGIQSIRDNAAYLSDERYWKVAAQS 296
            ...::    :|...|...:.|:::|:..||:  :|..:...|:.   ..:.|:::|.    ...:
Human   447 FLIYSGSNYQGPGGLVDYLDREVIPDFLGGE--SVCNVPEGGLV---PKSLYMTEEE----QEHT 502

  Fly   297 KSRWSW 302
            ...|.|
Human   503 DQLWQW 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3091	NP_001284816.1	SEC14	101..262	CDD:238099	32/177 (18%)
SEC14L5	NP_055507.1	PRELI	17..173	CDD:309720
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..214
		CRAL_TRIO_N	243..288	CDD:215024	12/46 (26%)
		SEC14	306..479	CDD:214706	39/206 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810