DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3091 and Sec14l5

DIOPT Version :9

Sequence 1:	NP_001284816.1	Gene:	CG3091 / 31210	FlyBaseID:	FBgn0029608	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_001121197.1	Gene:	Sec14l5 / 665119	MGIID:	3616084	Length:	696	Species:	Mus musculus

Alignment Length:	306	Identity:	60/306 - (19%)
Similarity:	113/306 - (36%)	Gaps:	72/306 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LTDLVAWF-EANPNLPEKIEPIVMLRFLKCTAFDVERTKALAELNYCMRNK------------SP 77
            |..|..|. |.:.....|.|.|  ||||:...|.:::.:.:...:...|.:            .|
Mouse   246 LVQLRHWLQETHKGKIPKDEHI--LRFLRARDFHLDKARDMLCQSLSWRKQHQVDLLLQTWRPPP 308

  Fly    78 HLFMDRNMEDEMTAEGLRVSDLLILPGVTPQGNKLIFFRMADLDPR--TRNSVEETKIFVMMSDA 140
            .|       .|..|.|....|:        .|..|...|:..:|.:  .:...||..:..::|
Mouse   309 PL-------QEFYAGGWHYQDI--------DGRPLYILRLGQMDTKGLMKAVGEEALLQHVLS-- 356

  Fly   141 RFTKPDVERETGSGADYVLDEADIAEGDVQ-----------IVDIGGYTLRHLAYVSIFVLRVYM 194
                   ..|.|...         .||:.:           ::|:.|..:|||....:..|...:
Mouse   357 -------VNEEGQKR---------CEGNTRQFGRPISSWTCLLDLEGLNMRHLWRPGVKALLRMI 405

  Fly   195 KFLQEAYPSRLQAMHVINCPTYLDKLISMMSPFLREEVRNMIRYHT----EGMDSLYKEVPRDML 255
            :.:::.||..|..:.::..|.....|.:::|||:.|..|.....::    :|...|...:.:|::
Mouse   406 EVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINENTRRKFLIYSGSNYQGPGGLVDYLDKDVI 470

  Fly   256 PNEYGGKAGTVAELKAKGIQSIRDNAAYLSDERYWKVAAQSKSRWS 301
            |:..||:  :|..:...|:.   ..:.||::|.  :..|....:||
Mouse   471 PDFLGGE--SVCNVPEGGMV---PKSLYLTEEE--QEQADQLQQWS 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3091	NP_001284816.1	SEC14	101..262	CDD:238099	32/177 (18%)
Sec14l5	NP_001121197.1	PRELI	17..173	CDD:368069
		CRAL_TRIO_N	243..288	CDD:215024	12/43 (28%)
		SEC14	306..479	CDD:214706	39/207 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900