DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3091 and sec14l8

DIOPT Version :9

Sequence 1:	NP_001284816.1	Gene:	CG3091 / 31210	FlyBaseID:	FBgn0029608	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_001093463.1	Gene:	sec14l8 / 558964	ZFINID:	ZDB-GENE-060526-180	Length:	395	Species:	Danio rerio

Alignment Length:	263	Identity:	54/263 - (20%)
Similarity:	112/263 - (42%)	Gaps:	42/263 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 SDKLTDL-VAWFEANPNLPEKIEPIV----------MLRFLKCTAFDVERTKALAELNYCMRNKS 76
            |.::.|| |...||.....||::.::          :||:|:...|::::::|:..
Zfish     2 SGRVGDLSVKQAEALAQFREKVQDVLPQCPSQSDHFLLRWLRARNFNLQKSEAMLR--------- 57

  Fly    77 PHLFMDRNME-DEMTAEGL--RVSDLLILPGV---TPQGNKLIFFRMADLDPR--TRNSVEETKI 133
            .|:...::|: |.:|.|..  .|.|..:..|:   ..:|:.:.:..:..|||:  ..::.::..|
Zfish    58 KHIEFRKHMKVDTITTEWQVPEVIDKYLSGGMCGHDREGSPVWYDVIGPLDPKGLMHSASKQDLI 122

  Fly   134 FVMMSDARFTKPDVERET---GSGADYVLDEADIAEGDVQIVDIGGYTLRHLAYVSIFVLRVYMK 195
            ...:.|....:.|.:|::   |...:.:          ..:.|..|..::||...:|......:.
Zfish   123 KSKVRDCEILQKDCDRQSERLGRNIESI----------TMVYDCEGLGMKHLYKPAIETYGEVLT 177

  Fly   196 FLQEAYPSRLQAMHVINCPTYLDKLISMMSPFLREEV-RNMIRYHTEGMDSLYKEVPRDMLPNEY 259
            ..::.||..|:.:.||..|.......:::..||.|:. |.:|...:...:.|.|.:..:.||..|
Zfish   178 MFEDNYPEGLKRLFVIKAPKLFPVAYNLVKHFLSEDTRRKVIVLGSNWQEVLQKYIDPEELPAYY 242

  Fly   260 GGK 262
            |||
Zfish   243 GGK 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3091	NP_001284816.1	SEC14	101..262	CDD:238099	32/169 (19%)
sec14l8	NP_001093463.1	CRAL_TRIO_N	13..59	CDD:215024	9/54 (17%)
		SEC14	78..246	CDD:214706	36/178 (20%)
		GOLD_2	304..382	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810