DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3091 and Clvs2

DIOPT Version :9

Sequence 1:	NP_001284816.1	Gene:	CG3091 / 31210	FlyBaseID:	FBgn0029608	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_780657.1	Gene:	Clvs2 / 215890	MGIID:	2443223	Length:	327	Species:	Mus musculus

Alignment Length:	269	Identity:	66/269 - (24%)
Similarity:	131/269 - (48%)	Gaps:	44/269 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 APET--------SASPATGWSD--KLTDLVAWFEANPNLP-EKIEPIVMLRFLKCTAF-DVERTK 63
            :|||        :.:|.|...|  ::.|:|.   ..|::. .:.:...:||||:...| ..|..:
Mouse     9 SPETLEKARLELNENPDTLHQDIQEVRDMVI---TRPDIGFLRTDDAFILRFLRARKFHHFEAFR 70

  Fly    64 ALAE-LNYCMRNKSPHLFMDRNMEDEMTAEGLRVSDLLILPGVTPQGNKLIFFRMADLDPRTRNS 127
            .||: ..|..:|      :|.....:.|..|::.:    |....|.|       :|:||...|
Mouse    71 LLAQYFEYRQQN------LDMFKSFKATDPGIKQA----LKDGFPGG-------LANLDHYGR-- 116

  Fly   128 VEETKIFVMMS----DARFTKPDVERETGSGADYVLDEADI-AEGDVQIVDIGGYTLRHLAYVSI 187
                ||.|:.:    .:|:|..|:.|......:.::::.:: ..|.|.|:|...:|.:..:.::.
Mouse   117 ----KILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTP 177

  Fly   188 FVLRVYMKFLQEAYPSRLQAMHVINCPTYLDKLISMMSPFLREEVRNMIRYHTEGMDSLYKEVPR 252
            .:||:.::.||:::|:|...:|.:|.|.|:..|.:::.|||:|:.|..|..|...::||::.:..
Mouse   178 NMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHP 242

  Fly   253 DMLPNEYGG 261
            ::||:|:||
Mouse   243 EILPSEFGG 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3091	NP_001284816.1	SEC14	101..262	CDD:238099	44/166 (27%)
Clvs2	NP_780657.1	CRAL_TRIO_N	29..75	CDD:215024	12/48 (25%)
		SEC14	106..251	CDD:238099	40/157 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835972
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	1	1.000	-	-		FOG0000233
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750