DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3091 and ctg-2

DIOPT Version :9

Sequence 1:	NP_001284816.1	Gene:	CG3091 / 31210	FlyBaseID:	FBgn0029608	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_001254156.1	Gene:	ctg-2 / 174360	WormBaseID:	WBGene00011756	Length:	408	Species:	Caenorhabditis elegans

Alignment Length:	358	Identity:	81/358 - (22%)
Similarity:	144/358 - (40%)	Gaps:	98/358 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TGDKDSAPETSASPATGWSDKLTDLVAWFEANPNLPEKIEPI-------VMLRFLKCTAFDVERT 62
            :|::.|   ||....|....||.|     |....:.:::|.:       .::|:|  ..:|.:..
Worm     9 SGERMS---TSTGEITESDRKLLD-----ELRKRIHKELELVKEYDDDFSLMRWL--IGWDRKID 63

  Fly    63 KALAELNYCMRNKSPH-LFMDRNMEDEMTAEGL--RVSD----LLILPGV---TPQGNKLIFFRM 117
            ..:.::.:.:|  :.| |.:|:  ||..|.|.:  :..|    |..|||.   ....|.::..:|
Worm    64 VVVPKIKFSLR--AIHALGLDQ--EDLSTLEKVAQKCDDCSVPLRYLPGSLIGLDHENNVVSLQM 124

  Fly   118 ------ADLDPRTRNS------VEETKIFVMMSDARFTKPDVERETGSGADYVLDEADIAEGDVQ 170
                  |.|.|.||||      :.|::  .:|...|    .:|:|.|...           |...
Worm   125 IGHLDAAGLMPATRNSDLYRMRIAESE--GVMQIIR----KMEKEQGKPL-----------GTSV 172

  Fly   171 IVDIGGYTLRHLAYVSIFVLRVYMKFLQEAYPSRLQAMHVINCPTYLDKLISMMSPFLREEVRNM 235
            |.|:.|.::..:...::.|:...:..|||.:|..::.:.::|.||::..|.||:||.|.::.:..
Worm   173 IFDLDGLSMVQIDLAALKVVTTMLSQLQEMFPDVIRKIFIVNTPTFIQVLWSMISPCLAKQTQQK 237

  Fly   236 IR-YHTEGMDSLYKEVPRDMLPNEYGG--KAGT-----------VAELKAKGIQSIRDNAAYLSD 286
            :: ...:....|.:.:..::|...:||  ||.|           .||||       .|.|..|..
Worm   238 VKILGNDWKQHLKENIGEEVLFERWGGTRKAETEYGNVRMGGKIPAELK-------YDPANDLPA 295

  Fly   287 ERYWK--VAAQS---------------KSRWSW 302
            |:..|  |:|:|               |..|.|
Worm   296 EKLTKLNVSARSTTFVPITLEGNVPGRKLYWWW 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3091	NP_001284816.1	SEC14	101..262	CDD:238099	40/178 (22%)
ctg-2	NP_001254156.1	SEC14	98..267	CDD:214706	42/185 (23%)
ctg-2	NP_001254156.1	EMP24_GP25L	331..>405	CDD:279450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910