DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3091 and CLVS1

DIOPT Version :9

Sequence 1:	NP_001284816.1	Gene:	CG3091 / 31210	FlyBaseID:	FBgn0029608	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_775790.1	Gene:	CLVS1 / 157807	HGNCID:	23139	Length:	354	Species:	Homo sapiens

Alignment Length:	220	Identity:	51/220 - (23%)
Similarity:	112/220 - (50%)	Gaps:	28/220 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 MLRFLKCTAF-DVERTKALAELNYCMRNKSPHLFMDRNMEDEMTAEGLRVSDLLILPGVTPQ--- 108
            :||||:...| ..:..:.||:. :..|..:..:|.:...:|    .|::.:.:...|||...
Human    76 ILRFLRARKFHQADAFRLLAQY-FQYRQLNLDMFKNFKADD----PGIKRALIDGFPGVLENRDH 135

  Fly   109 -GNKLIFFRMADLDPRTRNSVEETKIFVMMSDARFTKPDVERETGSGADYVLDEADI-AEGDVQI 171
             |.|::....|:.| ::|||              ||  |:.|......:.::::.:: ..|.:.|
Human   136 YGRKILLLFAANWD-QSRNS--------------FT--DILRAILLSLEVLIEDPELQINGFILI 183

  Fly   172 VDIGGYTLRHLAYVSIFVLRVYMKFLQEAYPSRLQAMHVINCPTYLDKLISMMSPFLREEVRNMI 236
            :|...::.:..:.::..:|::.::.||:::|:|...:|.:|.|.|:..|.:::.|||:::.|..|
Human   184 IDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRI 248

  Fly   237 RYHTEGMDSLYKEVPRDMLPNEYGG 261
            ..|...::||::.:..:.||:|:||
Human   249 FLHGNNLNSLHQLIHPEFLPSEFGG 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3091	NP_001284816.1	SEC14	101..262	CDD:238099	40/166 (24%)
CLVS1	NP_775790.1	CRAL_TRIO_N	51..97	CDD:215024	7/20 (35%)
		CRAL_TRIO	125..274	CDD:306996	40/166 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	333..354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145882
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	1	1.000	-	-		FOG0000233
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750