DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3191 and Sec14l2

DIOPT Version :9

Sequence 1:	NP_001245486.2	Gene:	CG3191 / 31209	FlyBaseID:	FBgn0023525	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	NP_653103.1	Gene:	Sec14l2 / 67815	MGIID:	1915065	Length:	403	Species:	Mus musculus

Alignment Length:	257	Identity:	52/257 - (20%)
Similarity:	98/257 - (38%)	Gaps:	50/257 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KQERDLKELLEWFRQN--DKLP--KEIDPLLLRRFYQCMFGDVEETRKLIEVNYALRNR------ 87
            |||    |.|..||:|  |.||  ...|...|.|:.:....|::::..::..:...|.:
Mouse    11 KQE----EALAKFRENVQDVLPTLPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDKI 71

  Fly    88 ---------HPHLFIKRDPLDADSKRT-FDYADILPLPGLTPDKCKVSLYCFREFEASK--MHHT 140
                     ..:|...|...|.|.... :|....|...||.             |.|||  :..|
Mouse    72 ISWQPPEVIQQYLSGGRCGYDLDGCPVWYDIIGPLDAKGLL-------------FSASKQDLLRT 123

  Fly   141 EDTRAFFMVSDCRFVTPDDLAKPDVLS---EGEVQIFDMKGTTMRHISRLTISTLRAYIKFLQLA 202
            :       :.||..:..:.:.:...|.   |....|:|.:|..::|:.:..:.....::...:..
Mouse   124 K-------MRDCELLLQECIQQTTKLGKKIETITMIYDCEGLGLKHLWKPAVEAYGEFLTMFEEN 181

  Fly   203 FPVRLRAIHMINCPTYLDRIVSVVKPFISDEV-FKLIRFHTQSINTLYEFVPREMLPEEYGG 263
            :|..|:.:.::..|.......:::|||:|::. .|::.........|.:.:..:.||.||||
Mouse   182 YPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRRKIMVLGANWKEVLLKHISPDQLPVEYGG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3191	NP_001245486.2	SEC14	114..263	CDD:238099	28/154 (18%)
Sec14l2	NP_653103.1	CRAL_TRIO_N	13..59	CDD:215024	13/49 (27%)
		SEC14	76..244	CDD:214706	36/188 (19%)
		GOLD_2	300..381	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810