DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3191 and sec14l1

DIOPT Version :9

Sequence 1:	NP_001245486.2	Gene:	CG3191 / 31209	FlyBaseID:	FBgn0023525	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	XP_012825399.2	Gene:	sec14l1 / 100124776	XenbaseID:	XB-GENE-5823346	Length:	717	Species:	Xenopus tropicalis

Alignment Length:	336	Identity:	66/336 - (19%)
Similarity:	124/336 - (36%)	Gaps:	90/336 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ASGTSEQLQRE---QDSDTSE---------QAVRKQERDLKELLEWFRQN------------DKL 51
            |...|..|..|   .|:|..|         |....||..|..|.:|.::.            :|:
Frog   216 ADAGSHSLAAEPSTPDTDKLEADYIERYLGQLTPMQESALIHLRQWLQETHKGKSEAGEWKPEKI 280

  Fly    52 PKEIDPLLLRRFYQCMFGDVEETRKLIEVNYALRNRHPHLFIKRDPLDADSKRTFDYADILPLPG 116
            ||:...|   ||.:....::|:.|:::..:.:.|.:|                ..||.    |..
Frog   281 PKDEHIL---RFLRARDFNMEKAREMLCQSLSWRKQH----------------QVDYI----LQT 322

  Fly   117 LTPDKCKVSLYCFREFEASKMH-HTEDTRAFFMVS----DCRFVTP---DDLAKPDVLS---EGE 170
            ..|.:      ...|:.|...| |.:|.|..:::.    |.:.:..   ::.....|||   ||:
Frog   323 WQPPR------VLEEYYAGGWHYHDKDGRPLYILRLGQVDTKGLVKALGEEAILRHVLSINEEGQ 381

  Fly   171 VQ-----------------IFDMKGTTMRHISRLTISTLRAYIKFLQLAFPVRLRAIHMINCPTY 218
            .:                 :.|::|..|||:.|..:..|...|:.::..:|..|..:.::..|..
Frog   382 KRCEENTRQFGRPIWSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLIVRAPRV 446

  Fly   219 LDRIVSVVKPFISDEVFKLIRFHT----QSINTLYEFVPREMLPEEYGGGAGSLEALRTHTQKAL 279
            ...:.::|.|||::...:....::    |....:.::|.:|::|:..||     |.:....:..|
Frog   447 FPVLWTLVSPFINENSRQKFLIYSGNNYQGPGGIADYVDKEIVPDFLGG-----ECVCNIPEGGL 506

  Fly   280 VEHRDYLMDPD 290
            |....|..|.|
Frog   507 VPKSLYQSDED 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3191	NP_001245486.2	SEC14	114..263	CDD:238099	33/180 (18%)
sec14l1	XP_012825399.2	PRELI	17..173	CDD:398400
		CRAL_TRIO_N	252..307	CDD:215024	12/57 (21%)
		CRAL_TRIO	332..496	CDD:395525	32/168 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910