Protein Alignment kz and hrpA

DIOPT Version :10

• Sequence 1: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_415931.4
• Gene: hrpA / 948444
• ECOCYCID: G6732
• Length: 1300
• Species: Escherichia coli
• Alignment Length: 1000
• Identity: 270/1000 - (27%)
• Similarity: 431/1000 - (43%)
• Gaps: 244/1000 - (24%)

  Fly   226 IKKLKPEPNPPACIHQTVYVPVHRTTEVQNAR----LR------------LPILAEEQQVMETIN 274
            :||:|   ||.|  .|.::..:.:  |:..|.    ||            ||:..::|.::|.|.
E. coli    34 VKKVK---NPDA--QQAIFQEMAK--EIDQAAGKVLLREAARPEITYPDNLPVSQKKQDILEAIR 91

  Fly   275 ENPIVIVAGETGSGKTTQLPQFLYEAGYAQHKMIGVTEPRRVAAIAMSKRVAHEMNL-PESEVSY 338
            ::.:||||||||||||||||:...|.|.....:||.|:|||:||..::.|:|.|:.. |...:.|
E. coli    92 DHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGY 156

  Fly   339 LIRFEGNVTPATRIKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRH 403
            .:||..:|:..|.:|.||||:||.||:.|.||.:|..||:|||||||:..|.|:|.|..::|
E. coli   157 KVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLP--- 218

  Fly   404 KRGQPLKLIIMSATLRVSDFTENTRLFKIPPPLLKVEARQFPVTIHFQK--RTPDDYVAEAYRKT 466
             |...||:||.|||:....|:.:..    ..|:::|..|.:||.:.::.  ...||...:..:..
E. coli   219 -RRPDLKIIITSATIDPERFSRHFN----NAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQAI 278

  Fly   467 LKIHNKLPE---GGILIFVTGQQEVNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAA 528
            ....::|.:   |.||||::|::|:                                .:|.|
E. coli   279 FDAVDELSQESHGDILIFMSGEREI--------------------------------RDTAD--- 308

  Fly   529 STVEDPKELEFDMKRVIRNIRKSKKKFLAQMALPKINLDDYKLPGDDTEADMHEQPDEDDEQEGL 593
                                           ||.|:||             .|.:
E. coli   309 -------------------------------ALNKLNL-------------RHTE---------- 319

  Fly   594 EEDNDDELGLEDESGMGSGQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTI 658
                                     :||||:.||:.:|||:| ....|.|: |::|||||||||:
E. coli   320 -------------------------ILPLYARLSNSEQNRVF-QSHSGRRI-VLATNVAETSLTV 357

  Fly   659 PHIKYVVDCGRQKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYSSAVYNDCF- 722
            |.||||:|.|..:...|...|.|....:...|:|||:||.||.||:|.|.|.||||    .|.|
E. coli   358 PGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYS----EDDFL 418

  Fly   723 --EDFSQPDIQKKPVEDLMLQMRCMGIDRVVHFPFPSPPDQVQLQAAERRLIVLGALEVAKTENT 785
              .:|:.|:|.:..:..::|||..:|:..:..|||...||:..:|...|.|..|||:   .|:..
E. coli   419 SRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRLLEELGAI---TTDEQ 480

  Fly   786 DLPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLPYTVCLVAALSVQEVLIETGVQRDEDVAPG 850
            .....:|.||..:|:.||.||..:|:..:.:...:...:.:.:|||:|:.. |..:.:.:.....
E. coli   481 ASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVREAMIITSALSIQDPR-ERPMDKQQASDEK 544

  Fly   851 ANRFHRKRQSWAASGNYQLLGDPMVLLRAVGAAEYAGSQGRLPEFCAANGLRQKAMSEVRKLRVQ 915
            ..|||.|...:.|..|         |...:|..:.|.|.......|..:.|....:.|.:.:..|
E. coli   545 HRRFHDKESDFLAFVN---------LWNYLGEQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQ 600

  Fly   916 LTNEINLNVSDVELGVDPELKPPTDAQARFLRQILLAGMGDRVARKVPLADIADKEE---RRRLK 977
            |...:.      |||:....:|   |:.|.:...||.|:...:..|     .|||:|   .|..:
E. coli   601 LRQVVK------ELGIPVNSEP---AEYREIHIALLTGLLSHIGMK-----DADKQEYTGARNAR 651

  Fly   978 YAYNCADMEEPAFLHVSSVLRQKAPEWVIYQEAYELQNGDSTKMFIRGITAIEPEWLLLYVPLLC 1042
            ::           :...|.|.:|.|:||:..|..|     :::::.|....|:|||:   .|:..
E. coli   652 FS-----------IFPGSGLFKKPPKWVMVAELVE-----TSRLWGRIAARIDPEWV---EPVAQ 697

  Fly  1043 NIREVREDPAPRFDKTSGKIFCHVDATFGKSGWELPL---GEVEMPLSEKACC---YFGMFLLDG 1101
            ::.: |....|.:::..|.:.    ||...:.:.||:   .:|.....:.|.|   :....|::|
E. coli   698 HLIK-RTYSEPHWERAQGAVM----ATEKVTVYGLPIVAARKVNYSQIDPALCRELFIRHALVEG 757

  Fly  1102 EVCSRLADFRSKLKSTPASVIKSWSSMNNKVLRFKRALITKQIHNRQALIDQWNSDPHFLLEEY- 1165
            :..:|.|.||..||                 ||.:...:..:...|..|:|.     ..|.|.|
E. coli   758 DWQTRHAFFRENLK-----------------LRAEVEELEHKSRRRDILVDD-----ETLFEFYD 800

  Fly  1166 QNLLYDV-ALSELTPLWPPVDKKEP 1189
            |.:.:|| :.......|..|.::.|
E. coli   801 QRISHDVISARHFDSWWKKVSRETP 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	232/822 (28%)
		DEXHc_DHX37	260..439	CDD:350740	77/179 (43%)
hrpA	NP_415931.4	PRK11131	5..1298	CDD:182986	269/999 (27%)