Protein Alignment kz and PRP22

DIOPT Version :9

• Sequence 1: NP_001284815.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_010929.3
• Gene: PRP22 / 856732
• SGDID: S000000815
• Length: 1145
• Species: Saccharomyces cerevisiae
• Alignment Length: 968
• Identity: 257/968 - (26%)
• Similarity: 429/968 - (44%)
• Gaps: 224/968 - (23%)

  Fly    81 VDKKKKKEGRAQLLGDLAAVQIPEEELQQYTSISQVQTVGLKRLPTLDEYLAKKKERQAQVLAEK 145
            ||.|.:::.|.:.  |...|::..::..::....||:  |.|:      |...|..:..:....:
Yeast   344 VDSKLEEQQRDET--DEIDVELNTDDGPKFLKDQQVK--GAKK------YEMPKITKVPRGFMNR 398

  Fly   146 SSASGLRVNAIKGSKRKLLVEEEEELQAKRKNPNVISVEEDDEDSSSSDEDDEEAPAQSAPIAIP 210
            |:.:|  .|||:..:       ||:|:.||:....|..::..:|.:.:.:|..
Yeast   399 SAING--SNAIRDHR-------EEKLRKKREIEQQIRKQQSFDDPTKNKKDSR------------ 442

  Fly   211 TPVSIAPPQIAVKPPIKKLKPEPNPPACIHQTVYVPVHRTTEVQNARLRLPILAEEQQVMETINE 275
            ..:.:...|:.|      .:.|.|.   :::::......:..:...|..||:.|...::::.:.:
Yeast   443 NEIQMLKNQLIV------TEWEKNR---MNESISYGKRTSLPISAQRQTLPVYAMRSELIQAVRD 498

  Fly   276 NPIVIVAGETGSGKTTQLPQFLYEAGYAQHKMIGVTEPRRVAAIAMSKRVAHEMNLPES-EVSYL 339
            |..:::.||||||||||:.|:|.|.|::.:.|||.|:||||||::::||||.|:..... :|.|.
Yeast   499 NQFLVIVGETGSGKTTQITQYLDEEGFSNYGMIGCTQPRRVAAVSVAKRVAEEVGCKVGHDVGYT 563

  Fly   340 IRFEGNVTPATRIKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHK 404
            ||||....|.||||:||||:|.:|...|..:||||||:|||||||:|.||:|..||.:....|.:
Yeast   564 IRFEDVTGPDTRIKYMTDGMLQREALLDPEMSKYSVIMLDEAHERTVATDVLFALLKKAAIKRPE 628

  Fly   405 RGQPLKLIIMSATLRVSDFTENTRLFKIPPPLLKVEARQFPVTIHFQKRTPDDYVAEAYRKTLKI 469
                ||:|:.||||..:.|:|    :.:..|::.:..:.|||.:.:.:....||:..|....:.|
Yeast   629 ----LKVIVTSATLNSAKFSE----YFLNCPIINIPGKTFPVEVLYSQTPQMDYIEAALDCVIDI 685

  Fly   470 HNKLPEGGILIFVTGQQEVNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDP 534
            |.....|.||:|:|||:|::...
Yeast   686 HINEGPGDILVFLTGQEEIDSCC------------------------------------------ 708

  Fly   535 KELEFDMKRVIRNIRKSKKKFLAQMALPKINLDDYKLPGDDTEADMHEQPDEDDEQEGLEEDNDD 599
             |:.:|..:.:                                                    .|
Yeast   709 -EILYDRVKTL----------------------------------------------------GD 720

  Fly   600 ELGLEDESGMGSGQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYV 664
            .:|             .|.:||:||.|.||.|::||.|.|.|.|..|.:||:||||:||..|.||
Yeast   721 SIG-------------ELLILPVYSALPSEIQSKIFEPTPKGSRKVVFATNIAETSITIDGIYYV 772

  Fly   665 VDCGRQKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYS-SAVYNDCFEDFSQP 728
            ||.|..|..:|:...|:...:|:..|:|.|:||.|||||...|.|||||: ||.||:..|: :.|
Yeast   773 VDPGFAKINIYNARAGIEQLIVSPISQAQANQRKGRAGRTGPGKCYRLYTESAFYNEMLEN-TVP 836

  Fly   729 DIQKKPVEDLMLQMRCMGIDRVVHFPFPSPPDQVQLQAAERRLIVLGAL-EVAKTENTDLPPAVT 792
            :||::.:...:|.::.|||:.::.|.|..||.         :.::|.|| |:...::.|....:|
Yeast   837 EIQRQNLSHTILMLKAMGINDLLKFDFMDPPP---------KNLMLNALTELYHLQSLDDEGKLT 892

  Fly   793 RLGHVISRFPVAPRFGKMLALSHQQNLLPYTVCLVAALSVQEVLI---ETGVQRDEDVAPGANRF 854
            .||..:|.||:.|...:.|..|.........|.:::.||||.|..   :..::.|...|    :|
Yeast   893 NLGKEMSLFPMDPTLSRSLLSSVDNQCSDEIVTIISMLSVQNVFYRPKDRQLEADSKKA----KF 953

  Fly   855 HRKRQSWAASGNYQLLGDPMVLLRAVGAAEYAGSQGRLPEFCAANGLRQKAMSEVRKLRVQLT-- 917
            |..            .||.:.||......:.|...   .::|..|.|..:.:...|.::.|::
Yeast   954 HHP------------YGDHLTLLNVYTRWQQANYS---EQYCKTNFLHFRHLKRARDVKSQISMI 1003

  Fly   918 -NEINLNVSDVELGVDPELKPPTDAQARFLRQILLAGMGDRVARKVPLADIADKEERRRLKYAYN 981
             .:|.|.:  :....||:|          :|:..::|.....|             :|..:..|.
Yeast  1004 FKKIGLKL--ISCHSDPDL----------IRKTFVSGFFMNAA-------------KRDSQVGYK 1043

  Fly   982 CADMEEPAFLHVSSVLRQKAPEWVIYQEAYELQNGDSTKMFIRGITAIEPEWLLLYVP 1039
            ..:......:|.||.|..|..|:|:|.....     :::.::..:|:|||:|||...|
Yeast  1044 TINGGTEVGIHPSSSLYGKEYEYVMYHSIVL-----TSREYMSQVTSIEPQWLLEVAP 1096

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_001284815.1	HrpA	237..1058	CDD:224557	228/812 (28%)
		DEXDc	279..418	CDD:238005	72/139 (52%)
		P-loop_NTPase	369..>500	CDD:304359	46/130 (35%)
		HELICc	619..704	CDD:197757	42/84 (50%)
		HA2	774..859	CDD:214852	24/88 (27%)
		OB_NTP_bind	915..1039	CDD:285018	26/126 (21%)
PRP22	NP_010929.3	Pnp	1..423	CDD:224106	22/97 (23%)
		HrpA	456..1145	CDD:224557	230/819 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810