Protein Alignment kz and PRP43

DIOPT Version :9

• Sequence 1: NP_001284815.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_011395.1
• Gene: PRP43 / 852757
• SGDID: S000003088
• Length: 767
• Species: Saccharomyces cerevisiae
• Alignment Length: 880
• Identity: 265/880 - (30%)
• Similarity: 384/880 - (43%)
• Gaps: 218/880 - (24%)

  Fly   210 PTPVSIAPPQIA--VKPPIKKLKPEPNPPACIHQTV----------------------------- 243
            |.||..:.|:.|  :...:.|..|.|:....:|...
Yeast    12 PDPVETSIPEQAAEIAEELSKQHPLPSEEPLVHHDAGEFKGLQRHHTSAEEAQKLEDGKINPFTG 76

  Fly   244 --YVPVHRTTEVQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLY--EAGYAQ 304
              :.|  :..::...|..||:.|:..:.::....|.|::..||||||||||:|||:.  |..:.:
Yeast    77 REFTP--KYVDILKIRRELPVHAQRDEFLKLYQNNQIMVFVGETGSGKTTQIPQFVLFDEMPHLE 139

  Fly   305 HKMIGVTEPRRVAAIAMSKRVAHEMNLP-ESEVSYLIRFEGNVTPATRIKFMTDGVLLKEIETDF 368
            :..:..|:||||||:::::|||.||::. ..||.|.||||...:..|.:|:||||:||:|...|.
Yeast   140 NTQVACTQPRRVAAMSVAQRVAEEMDVKLGEEVGYSIRFENKTSNKTILKYMTDGMLLREAMEDH 204

  Fly   369 LLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHKRGQPLKLIIMSATLRVSDFTENTRLFKIP 433
            .||:||.|||||||||::.||||:|||.::|    ||...||:|||||||....|   .|.|. .
Yeast   205 DLSRYSCIILDEAHERTLATDILMGLLKQVV----KRRPDLKIIIMSATLDAEKF---QRYFN-D 261

  Fly   434 PPLLKVEARQFPVTIHFQKRTPDDYVAEAYRKTLKIHNKLPEGGILIFVTGQQEVNQLVRKLRRT 498
            .|||.|..|.:||.:::......||:..|.|..|:||.....|.||:|:||:.|:...|||:
Yeast   262 APLLAVPGRTYPVELYYTPEFQRDYLDSAIRTVLQIHATEEAGDILLFLTGEDEIEDAVRKI--- 323

  Fly   499 FPYHHAPTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKRVIRNIRKSKKKFLAQMALPK 563
                                                                             
Yeast   324 ----------------------------------------------------------------- 323

  Fly   564 INLDDYKLPGDDTEADMHEQPDEDDEQEGLEEDNDDELGLEDESGMGSGQRQPLWVLPLYSLLSS 628
                  .|.||.                           |..|.|.|     ||.|.|||..|..
Yeast   324 ------SLEGDQ---------------------------LVREEGCG-----PLSVYPLYGSLPP 350

  Fly   629 EKQNRIFLPVPDG-----CRLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVTY 688
            .:|.|||.|.|:.     .|..|:|||:|||||||..|.||||.|..|.::|:....|.:.:|:.
Yeast   351 HQQQRIFEPAPESHNGRPGRKVVISTNIAETSLTIDGIVYVVDPGFSKQKVYNPRIRVESLLVSP 415

  Fly   689 TSKASADQRAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQMRCMGIDRVVHF 753
            .|||||.||||||||...|.|:|||:...:.....:.|.|:|.:..:...:|:::.:|||.:|||
Yeast   416 ISKASAQQRAGRAGRTRPGKCFRLYTEEAFQKELIEQSYPEILRSNLSSTVLELKKLGIDDLVHF 480

  Fly   754 PFPSPPDQVQLQAAERRLIVLGALEVAKTENTDLPPAVTRLGHVISRFPVAPRFGKMLALSHQQN 818
            .|..||....:..|...|..|..|:    :..:|.|    ||.:.|:||:.|....||..|.:..
Yeast   481 DFMDPPAPETMMRALEELNYLACLD----DEGNLTP----LGRLASQFPLDPMLAVMLIGSFEFQ 537

  Fly   819 LLPYTVCLVAALSVQEVLIETGVQRDEDVAPGANRFHRKRQSWAASGNYQLLGDPMVLLRAVGA- 882
            .....:.:||.|||..|.|..  .:|:..|..|........           ||.:.||....|
Yeast   538 CSQEILTIVAMLSVPNVFIRP--TKDKKRADDAKNIFAHPD-----------GDHITLLNVYHAF 589

  Fly   883 -AEYAGSQGRLPEFCAANGLRQKAMSEVRKLRVQLTNEIN-----LNVSDVELGVDPELKPPTDA 941
             ::.|...| :.::|..:.|..:::|....:|.||...:|     ||.:|.|   .|:.
Yeast   590 KSDEAYEYG-IHKWCRDHYLNYRSLSAADNIRSQLERLMNRYNLELNTTDYE---SPKY------ 644

  Fly   942 QARF--LRQILLAGMGDRVARKVPLADIADKEERRRLKYAYNCADMEEPAFLHVSSVLRQKAPEW 1004
               |  :|:.|.:|...:||:|            |.....|......:...:|.|:||...| ||
Yeast   645 ---FDNIRKALASGFFMQVAKK------------RSGAKGYITVKDNQDVLIHPSTVLGHDA-EW 693

  Fly  1005 VIYQEAYELQNGDSTKMFIRGITAIEPEWLLLYVP 1039
            |||.| :.|    ::|.:||.:|::.||||:...|
Yeast   694 VIYNE-FVL----TSKNYIRTVTSVRPEWLIEIAP 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_001284815.1	HrpA	237..1058	CDD:224557	257/851 (30%)
		DEXDc	279..418	CDD:238005	73/141 (52%)
		P-loop_NTPase	369..>500	CDD:304359	59/130 (45%)
		HELICc	619..704	CDD:197757	45/89 (51%)
		HA2	774..859	CDD:214852	23/84 (27%)
		OB_NTP_bind	915..1039	CDD:285018	37/130 (28%)
PRP43	NP_011395.1	HrpA	55..753	CDD:224557	256/837 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810