Protein Alignment kz and YLR419W

DIOPT Version :9

• Sequence 1: NP_001284815.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_013523.3
• Gene: YLR419W / 851137
• SGDID: S000004411
• Length: 1435
• Species: Saccharomyces cerevisiae
• Alignment Length: 1371
• Identity: 301/1371 - (21%)
• Similarity: 493/1371 - (35%)
• Gaps: 414/1371 - (30%)

  Fly     3 KKVHNAKARQNPQTIVDNSAVKKIQIDVDAVAGGNQVGYDEANALVLPSEKRATKIKVDKVQHVK 67
            |..||....:.|:.:.:||    |.:|:|          :.:..|:..|.|.....:..|:.|..
Yeast   248 KNSHNPSLVRFPKKVWENS----IFVDLD----------ESSRQLIETSLKEKIDWQAKKISHKN 298

  Fly    68 ILSKKQRKHLQA---IVDKKKKKEGRAQLLGD---LAAVQIPEEELQQYTSISQVQT---VGLKR 123
            ....:.|:.|:|   .:..:.|....|.|..|   .....:||::|..:....:..|   |.:..
Yeast   299 ETIAENREDLKAKLLTLQFRPKHVEEAMLYKDPLSFLLFNLPEDDLPPFFHKKKGDTKNKVEITN 363

  Fly   124 LPTLDEYLAKKKERQAQV-LAEKSSASGLRVNAIKGSK------RKLL----------VEEEEEL 171
            ||.....:.   ||..:: ::...:...|:.|.:..::      |::|          |.|.|.:
Yeast   364 LPLSTRMIV---ERLTEIGVSSDEALLALQQNDMNENEAAGFLTREILPTLNSNTNEPVSETESI 425

  Fly   172 QAKRKNPNVISVEEDDEDSSSSDEDD--------------------EEAPAQSAPIAIPT----- 211
            :.  .|..:.|:|...|......::|                    :..||....|.:.|
Yeast   426 EC--WNQELESLESIYEGCVMDAKEDSHYTLNLIEKLKIKLKVYRTKNYPASLPGIVVSTFDKNY 488

  Fly   212 --PVSIAPPQIA-----------------------VKPPIKKLKPEPNP---------------- 235
              |..|....:.                       :|..|.|:...|.|
Yeast   489 KLPDYIKKQILTRLLHYLQEGNLIGDMLVYHIYEWLKENISKIIDNPGPLIPDSDSKGAINKRNI 553

  Fly   236 ---PACIHQTVYVPVHRTT-----------------------EVQNARLRLPILAEEQQVMETIN 274
               ...|:.:......:||                       .:|..|.:||...:::.:::.||
Yeast   554 SNGKRSINNSSSRKFTKTTISEDTLSVLREEYTKRIKSSEYKSMQLVREQLPAWKKQKVIIDIIN 618

  Fly   275 ENPIVIVAGETGSGKTTQLPQFLYE------AGYAQHKMIGVTEPRRVAAIAMSKRVAHEMNLP- 332
            :|.:|::.|||||||:||:.||:.:      ..:.:.|:: .|:|||::||.:::||:.|..:.
Yeast   619 KNEVVLITGETGSGKSTQVVQFILDFLQKEKGDFGKTKIV-CTQPRRISAIGLAERVSDERCVTC 682

  Fly   333 ESEVSYLIRFEGNVTPATRIKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDILVGLLSR 397
            ..||.|:||.......:|||||||.|||::.::....:.:.:::::||.||||:.||::|.|:..
Yeast   683 GEEVGYVIRGVNKTKASTRIKFMTTGVLVRLLQNARTMLENTIVVIDEVHERSIDTDLIVTLMKN 747

  Fly   398 IVPLRHKRGQPLKLIIMSATLRVSDFTENTRLFKIPPPL--LKVEARQFPVTIHFQ--------- 451
            :  |...||  :|:::||||:.|..|.      |..|.|  ..:|.|.||:|.:|.
Yeast   748 L--LHRVRG--MKIVLMSATVNVDLFK------KFFPGLATCHIEGRTFPITDYFLEDILSDLDF 802

  Fly   452 --KRT-----PDDYVAE-----AYRKTLKIHNKLPEGGILIFVTGQQEVNQLVRKLRRTFPYHHA 504
              ||.     .||.|.|     .|.|        |......|.:||...:.|.:.:.    |.|.
Yeast   803 KIKREKALSYDDDSVDERNNDDQYLK--------PRADSKFFTSGQINYDLLCQVVE----YVHK 855

  Fly   505 PTKDVAKNGKVSEEEKEETIDDAASTVEDPKELEFDMKRVIRNIRKSKKKFLAQMALP---KINL 566
            ..|....||.:.                                          :.||   :||.
Yeast   856 RLKAANDNGSII------------------------------------------VFLPGVGEINK 878

  Fly   567 DDYKLPGDDTEADMHEQPDEDDEQEGLEEDNDDELGLEDESGMGSGQRQPLWVLPLYSLLSSEKQ 631
            ....|.....|||                                     ..||||:|.|:.|.|
Yeast   879 CCNLLANKSNEAD-------------------------------------FMVLPLHSALTPEDQ 906

  Fly   632 NRIFLPVPDGCRLCVVSTNVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVTYTSKASADQ 696
            .|:|... .|.|..|||||:||||:||......:|.||.|:..|:.....:..:.::.|||...|
Yeast   907 KRVFKKY-HGKRKVVVSTNIAETSITIDDCVATIDTGRAKSMFYNPKDNTTKLIESFISKAEVKQ 970

  Fly   697 RAGRAGRISAGHCYRLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQMRCMGIDRVVHF-------- 753
            |.|||||:..|..|:|:|..:|.:.......|:|::.|:|.|.|.::.|||..|..|
Yeast   971 RRGRAGRVREGLSYKLFSKNLYENDMISMPIPEIKRIPLESLYLSVKAMGIKDVKAFLSTALDAP 1035

  Fly   754 PFPSPPDQVQLQAAERRLIVLGALEVAKTENTDLPPAVTRLGHVISRFPVA-PRFGKMLALSHQQ 817
            |.|:      ||.|||.|..:|.::       :...::|:||..||..||. .:.||:|......
Yeast  1036 PLPA------LQKAERILTTIGLVD-------ESDKSLTQLGQFISLMPVMDSKHGKLLIYGILF 1087

  Fly   818 NLLPYTVCLVAALSVQEVLIETGVQRDEDVAPGANRFHRKRQSWAASGNYQLLGDPMVLLRAVGA 882
            .....:|.||:.|.:             .|.|....|..:.:.......|:..||...:|..|..
Yeast  1088 GCTDISVLLVSILGI-------------GVLPFIGGFENREKIKKLLCKYESRGDLFAVLEIVRD 1139

  Fly   883 AEYAGSQGRLPEFCAANGLRQKAMSEVRKLRVQ---LTNEINLNVSDVELGVDPELKPPTDAQAR 944
            ...........::...|.|....::|::....|   :..::.....|.::|...:|. ..:....
Yeast  1140 YFKIKDSSIKRKYLRDNLLSYNKINEIKSSTAQYYSILKDVGFLPMDYKVGSISDLN-RNERNFD 1203

  Fly   945 FLRQILLAGMGDRVARKVPLADI----------------------------ADKEERRRLKYAYN 981
            .||.||.......:|| |.|.|:                            .||.|..:.|.:..
Yeast  1204 ILRAILTGAFYPHIAR-VQLPDVKYLSTSSGAVEKDPEAKMIKYWIRSEEYQDKLEEYKTKISQE 1267

  Fly   982 C--ADMEE------PAFLHVSSVL-----------------------RQKAPEWVIYQEAYELQN 1015
            .  .|:|:      .||:|.||||                       :.|.|..|.|.......:
Yeast  1268 TQKVDLEDLPLPATRAFIHPSSVLFSTNSVNLEDAKLLSEVDGPISRQSKIPTVVKYPFVLFTTS 1332

  Fly  1016 GDSTKMFIRGITAIEPEWLLLYVPLLCNIREVREDPAPRFDKTSGKIFCHVDATFGKSG-----W 1075
            ..:.|:::|.:|......|||:                     .|.|...:..|....|     |
Yeast  1333 QVTNKLYLRDLTPTTTLSLLLF---------------------GGAISYDIGGTIHSPGIVVDNW 1376

  Fly  1076 ELPLGEVEMPLSEKACCYFGMFLLDGEVCSRLAD-FRSKLKSTPASVIKSW--SSMNNKVLRFKR 1137
             ||:         :..|..|:.:  .|:.::|.: .|.||:| |....||.  :|..:|.|:...
Yeast  1377 -LPI---------RTWCKNGVLI--KELRTQLDEAIRKKLES-PDYAKKSQIDNSGADKTLKIVE 1428

  Fly  1138 ALITKQ 1143
            .:|..:
Yeast  1429 KIIASE 1434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_001284815.1	HrpA	237..1058	CDD:224557	226/947 (24%)
		DEXDc	279..418	CDD:238005	54/145 (37%)
		P-loop_NTPase	369..>500	CDD:304359	42/153 (27%)
		HELICc	619..704	CDD:197757	37/84 (44%)
		HA2	774..859	CDD:214852	18/85 (21%)
		OB_NTP_bind	915..1039	CDD:285018	36/185 (19%)
YLR419W	NP_013523.3	UBA_YLR419W_like	369..409	CDD:270457	5/42 (12%)
		RWD	426..528	CDD:399058	12/103 (12%)
		HrpA	563..1428	CDD:224557	246/1029 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810