DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kz and AT1G27900

DIOPT Version :9

Sequence 1:	NP_001284815.1	Gene:	kz / 31205	FlyBaseID:	FBgn0001330	Length:	1192	Species:	Drosophila melanogaster
Sequence 2:	NP_564296.1	Gene:	AT1G27900 / 839683	AraportID:	AT1G27900	Length:	700	Species:	Arabidopsis thaliana

Alignment Length:	822	Identity:	253/822 - (30%)
Similarity:	386/822 - (46%)	Gaps:	182/822 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 LPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYEAGYAQHKMIGVTEPRRVAAIAMSKR 324
            ||||..|::::||:.:|.:|::.|||||||:|||.|.|:..||.:..:|.:|:||||||:::::|
plant     4 LPILQFEEKIVETVEKNSVVVIIGETGSGKSTQLSQILHRHGYTKSGVIAITQPRRVAAVSVARR 68

  Fly   325 VAHEMNLPESE-VSYLIRFEGNVTPATRIKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYT 388
            ||.|:::|..| |.|.||||...|..||||::||||||:|..::.:|..|||||||||||||:.|
plant    69 VAQELDVPLGEDVGYAIRFEDRTTSKTRIKYLTDGVLLRESLSNPMLDDYSVIILDEAHERSLNT 133

  Fly   389 DILVGLLSRIVPLRHKRGQPLKLIIMSATL---RVSDFTENTRLFKIPPPLLKVEARQFPVTIHF 450
            |||:||:.|:|.:   |....|::|.||||   :||:|....       |:|.|..:.:||.|.:
plant   134 DILLGLVKRLVRI---RASNFKVLITSATLDGEKVSEFFSGC-------PVLNVPGKLYPVEILY 188

  Fly   451 QKRTPDDYVAEAYRKTLKIHNKLPEGGILIFVTGQQEVNQLVRKLRRTFPYHHAPTKDVAKNGKV 515
            .|..|..|:..:.:..:.||.:.|||.||||:|||.::.:||.:|
plant   189 SKERPVSYIESSLKVAIDIHVREPEGDILIFMTGQDDIEKLVSRL-------------------- 233

  Fly   516 SEEEKEETIDDAASTVEDPKELEFDMKRVIRNIRKSKKKFLAQMALPKINLDDYKLPGDDTEADM 580
              |||                        :|:
plant   234 --EEK------------------------VRS--------------------------------- 239

  Fly   581 HEQPDEDDEQEGLEEDNDDELGLEDESGMGSGQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLC 645
                                        :..|......:.||:..|..|.|.|:|.|.|..||..
plant   240 ----------------------------LAEGSCMDAIIYPLHGSLPPEMQVRVFSPPPPNCRRF 276

  Fly   646 VVSTNVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCY 710
            :||||:||||||:..:.||:|.|..|.|.|:..:|:.:..|...||..|:||||||||...|.||
plant   277 IVSTNIAETSLTVDGVVYVIDSGYVKQRQYNPSSGMFSLDVIQISKVQANQRAGRAGRTRPGKCY 341

  Fly   711 RLYSSAVYNDCFEDFSQPDIQKKPVEDLMLQMRCM---GIDRVVHFPFPSPPDQVQLQAAERRLI 772
            |||..|||.|.|.|.:.|:||:..:...:|.::.:   .|| ::.|.|...|....|:.|.::|.
plant   342 RLYPLAVYRDDFLDATIPEIQRTSLAGSVLYLKSLDLPDID-ILKFDFLDAPSSESLEDALKQLY 405

  Fly   773 VLGALEVAKTENTDLPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLPYTVCLVAALSVQEVLI 837
            .:.|::    ||    .|:||:|..:|..|:.|...:.|..:::...|...:.:||.||.:..|:
plant   406 FIDAID----EN----GAITRIGRTMSDLPLEPSLSRTLIEANETGCLSQALTVVAMLSAETTLL 462

  Fly   838 ETGVQRDEDVAPGANRFHRKRQSWAASGNYQLLGDPMVLLRAVGAAEYAGSQGRLPEFCAANGLR 902
            ....:..|     ..|.|.:..:......|   ||.:.||:...:.:.....   |.:|..||::
plant   463 PARSKPSE-----KKRKHDEDSNLPNGSGY---GDHIQLLQIFESWDRTNYD---PVWCKENGMQ 516

  Fly   903 QKAMSEVRKLRVQLTNEINLNVSD--VELGVDPELKPPTDAQARFLRQILLAGMGDRVARKVPLA 965
            .:.|..|:.:|.||. :|...:|.  :|:|.|.......| ..|.||:.|..|..:::|
plant   517 VRGMVFVKDVRRQLC-QIMQKISKDRLEVGADGRKSSSRD-DYRKLRKALCVGNANQIA------ 573

  Fly   966 DIADKEERRRLKYAYNCADMEEPAF-LHVSSVLRQ----KAPEWVIYQEAYELQNGDSTKMFIRG 1025
                  ||......|.....:.... :|.||||..    ..|.:|:|.|..     .:|:.|:|.
plant   574 ------ERMLRHNGYRTLSFQSQLVQVHPSSVLSADNDGMMPNYVVYHELI-----STTRPFMRN 627

  Fly  1026 ITAIEPEWLLLYVPL-----LCNIREVREDPAPRF----DKT 1058
            :.|::..|:   .|:     ..|:|::...|||.|    :||
plant   628 VCAVDMAWV---APIKRKIEKLNVRKLSGGPAPSFKVPEEKT 666

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_001284815.1	HrpA	237..1058	CDD:224557	251/820 (31%)
		DEXDc	279..418	CDD:238005	74/139 (53%)
		P-loop_NTPase	369..>500	CDD:304359	56/133 (42%)
		HELICc	619..704	CDD:197757	40/84 (48%)
		HA2	774..859	CDD:214852	20/84 (24%)
		OB_NTP_bind	915..1039	CDD:285018	31/130 (24%)
AT1G27900	NP_564296.1	HrpA	3..639	CDD:224557	244/793 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820