DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kz and EMB3011

DIOPT Version :9

Sequence 1:	NP_001284815.1	Gene:	kz / 31205	FlyBaseID:	FBgn0001330	Length:	1192	Species:	Drosophila melanogaster
Sequence 2:	NP_196805.2	Gene:	EMB3011 / 831141	AraportID:	AT5G13010	Length:	1255	Species:	Arabidopsis thaliana

Alignment Length:	1050	Identity:	282/1050 - (26%)
Similarity:	450/1050 - (42%)	Gaps:	252/1050 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 DEANALV------------LPSEKRATKIKVDKVQH--VKILSKKQRKHLQAIVDKKKKKEGRAQ 92
            ||.|:|.            ...:|:.|::....|:.  .|:...:.:|:.|...|..:.::.:..
plant   342 DEGNSLFDADSASFFLGDDASLQKKETELAKRLVRRDGSKMSLAQSKKYSQLNADNAQWEDRQLL 406

  Fly    93 LLGDLAAVQI-----PEEELQQYTSISQVQTVGLKRLPTLDEYLAKKKERQAQVLAEKSSASGLR 152
            ..|.:...::     .|||.:....:...:.      |.||..:...|:.: .|:..|...|.:.
plant   407 RSGAVRGTEVQTEFDSEEERKAILLVHDTKP------PFLDGRVVYTKQAE-PVMPVKDPTSDMA 464

  Fly   153 VNAIKGSKRKLLVEEEEELQAKRKN------------PNVISVEED----DEDSSSSDEDDEEAP 201
            :.:.|||.   ||:|..|.|:..|:            .|::.:|:.    |.|::...:|.|...
plant   465 IISRKGSG---LVKEIREKQSANKSRQRFWELAGSNLGNILGIEKSAEQIDADTAVVGDDGEVDF 526

  Fly   202 AQSAPIAIPTPVSIAPPQIAVKPPIKKLKPEPNPPACIHQTVYVPVHRTTEVQNARLRLPILAEE 266
            ...|..|.......|..:.|:.                         :|...|  |..|||.:..
plant   527 KGEAKFAQHMKKGEAVSEFAMS-------------------------KTMAEQ--RQYLPIFSVR 564

  Fly   267 QQVMETINENPIVIVAGETGSGKTTQLPQFLYEAGYAQHKMIGVTEPRRVAAIAMSKRVAHEMNL 331
            .::::.|.||.:::|.|||||||||||.|:|:|.||..:.::|.|:||||||::::|||:.||
plant   565 DELLQVIRENQVIVVVGETGSGKTTQLTQYLHEDGYTINGIVGCTQPRRVAAMSVAKRVSEEM-- 627

  Fly   332 PESE----VSYLIRFEGNVTPATRIKFMTDGVLLKEIETDFLLSKYSVIILDEAHERSVYTDILV 392
             |:|    :.|.||||....|.|.||:|||||||:|...|..|.||.|:::|||||||:.||:|.
plant   628 -ETELGDKIGYAIRFEDVTGPNTVIKYMTDGVLLRETLKDSDLDKYRVVVMDEAHERSLNTDVLF 691

  Fly   393 GLLSRIVPLRHKRGQPLKLIIMSATL---RVSDFTENTRLFKIPPPLLKVEARQFPVTIHFQKRT 454
            |:|.::|    .|.:..|||:.||||   :.|:|..:..:|.||       .|.|||.|.:.|..
plant   692 GILKKVV----ARRRDFKLIVTSATLNAQKFSNFFGSVPIFNIP-------GRTFPVNILYSKTP 745

  Fly   455 PDDYVAEAYRKTLKIHNKLPEGGILIFVTGQQEVNQLVRKLRRTFPYHHAPTKDVAKNGKVSEEE 519
            .:|||..|.::.:.||...|.|.||||:|||.|:......|:                     |.
plant   746 CEDYVEAAVKQAMTIHITSPPGDILIFMTGQDEIEAACFSLK---------------------ER 789

  Fly   520 KEETIDDAASTVEDPKELEFDMKRVIRNIRKSKKKFLAQMALPKINLDDYKLPGDDTEADMHEQP 584
            .|:.:..::              |.|.|
plant   790 MEQLVSSSS--------------REITN------------------------------------- 803

  Fly   585 DEDDEQEGLEEDNDDELGLEDESGMGSGQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRLCVVST 649
                                            |.:||:||.|.::.|.:||....||.|.|:|:|
plant   804 --------------------------------LLILPIYSQLPADLQAKIFQKPEDGARKCIVAT 836

  Fly   650 NVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCYRLYS 714
            |:||||||:..|.||:|.|..|.::::...|:.|..|...|:|::|||||||||...|.|||||:
plant   837 NIAETSLTVDGIYYVIDTGYGKMKVFNPRMGMDALQVFPISRAASDQRAGRAGRTGPGTCYRLYT 901

  Fly   715 SAVYNDCFEDFSQPDIQKKPVEDLMLQMRCMGIDRVVHFPFPSPPDQVQLQAAERRLIVLGALEV 779
            .:.|.:.......|:||:..:.:::|.::.:.||.::.|.|..||.|..:..:..:|.|||||
plant   902 ESAYLNEMLPSPVPEIQRTNLGNVVLLLKSLKIDNLLDFDFMDPPPQENILNSMYQLWVLGAL-- 964

  Fly   780 AKTENTDLPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLPYTVCLVAALSVQEVLIETGVQRD 844
               .|..   .:|.||..:..||:.|...|||.:..:.:.:...:.:|:.|||..|......:.:
plant   965 ---NNVG---GLTDLGWKMVEFPLDPPLAKMLLMGERLDCIDEVLTIVSMLSVPSVFFRPKERAE 1023

  Fly   845 EDVAPGANRFHRKRQSWAASGNYQLLGDPMVLLRAVGAAEYAGSQGRLPEFCAANGLRQKAMSEV 909
            |..|.....|..:.........||...:          .:|.|      ::|..:.|:.|.:.:.
plant  1024 ESDAAREKFFVPESDHLTLLNVYQQWKE----------HDYRG------DWCNDHYLQVKGLRKA 1072

  Fly   910 RKLRVQLTNEI-NLNVSDVELGVDPELKPPTDAQARFLRQILLAGMGDRVARKVPLADIADKEER 973
            |::|.||.:.: .|.:.....|.|.::.......|.|.....|.|:|:.|
plant  1073 REVRSQLLDILKQLKIELRSCGPDWDIVRKAICSAYFHNSARLKGVGEYV--------------- 1122

  Fly   974 RRLKYAYNCADMEEPAFLHVSSVL--RQKAPEWVIYQEAYELQNGDSTKMFIRGITAIEPEWLLL 1036
                   ||. ...|..||.||.|  ....|::|:|.|...     :||.:::..|::||.||..
plant  1123 -------NCR-TGMPCHLHPSSALYGLGYTPDYVVYHELIL-----TTKEYMQCATSVEPHWLAE 1174

  Fly  1037 YVPLLCNIRE 1046
            ..|:..::::
plant  1175 LGPMFFSVKD 1184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kz	NP_001284815.1	HrpA	237..1058	CDD:224557	241/819 (29%)
		DEXDc	279..418	CDD:238005	73/142 (51%)
		P-loop_NTPase	369..>500	CDD:304359	53/133 (40%)
		HELICc	619..704	CDD:197757	40/84 (48%)
		HA2	774..859	CDD:214852	22/84 (26%)
		OB_NTP_bind	915..1039	CDD:285018	30/126 (24%)
EMB3011	NP_196805.2	DUF1777	158..>247	CDD:285811
		DEXDc	553..739	CDD:214692	92/201 (46%)
		DEXDc	575..713	CDD:238005	73/144 (51%)
		HELICc	806..892	CDD:197757	41/85 (48%)
		HA2	961..1043	CDD:214852	22/89 (25%)
		OB_NTP_bind	1077..1177	CDD:285018	30/127 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820